公开(公告)号：US20220064492A1

公开(公告)日：2022-03-03

申请号：US17413022

申请日：2019-12-10

Applicant: NITTO DENKO CORPORATION

Inventor： Noboru YOSHIDA ,  Eriko ABE ,  Ryuhei ARIMA

IPC: C09J7/38 ,  C09J11/08 ,  A61M25/02 ,  A61L29/14 ,  A61L29/04

Abstract: A tape or sheet for sticking to skin, which includes a base material and an adhesive layer laminated on at least one surface of the base layer, wherein the adhesive layer contains an acrylic copolymer obtained by copolymerizing a monomer mixture including a (meth)acrylic acid alkyl ester monomer and an alkoxy group-containing ethylenically unsaturated monomer, a component that is liquid or paste-like at room temperature, and a tackifier, and wherein the tackifier includes a rosin ester.

公开(公告)号：US20160367494A1

公开(公告)日：2016-12-22

申请号：US15185657

申请日：2016-06-17

Applicant: NITTO DENKO CORPORATION

Inventor： Yu TACHIKAWA ,  Satoshi AMEYAMA ,  Eriko ABE ,  Tetsuya NAKAMURA ,  Naoko URUSHIHARA ,  Jun ISHIKURA ,  Kazuhiro AOYAGI ,  Yoshitaka INOUE ,  Akira YOKOUCHI ,  Tomoya TANAKA

IPC: A61K9/70 ,  A61K31/27 ,  A61K31/428 ,  A61K31/137 ,  A61K47/14

CPC classification number: A61K9/7061 ,  A61K31/137 ,  A61K31/27 ,  A61K31/428 ,  A61K47/14 ,  A61L15/44 ,  A61L15/58 ,  C08L33/06

Abstract: A patch preparation includes a support and a pressure-sensitive adhesive layer formed on one surface of the support. The pressure-sensitive adhesive layer includes: (A) a polymer prepared by copolymerizing monomer components including a hydroxyl group-containing monomer and an alkyl (meth)acrylate monomer; (B) a polymer prepared by copolymerizing monomer components including a methyl methacrylate monomer and a butyl methacrylate monomer; and (C) a basic drug, provided that bisoprolol and a salt thereof are excluded.

Abstract translation: 贴片制剂包括支撑体和形成在支撑体的一个表面上的压敏粘合剂层。 压敏粘合剂层包括：（A）通过使包含含羟基的单体和（甲基）丙烯酸烷基酯单体的单体成分共聚而制备的聚合物; （B）通过使包含甲基丙烯酸甲酯单体和甲基丙烯酸丁酯单体的单体组分共聚制备的聚合物; 和（C）碱性药物，条件是排除比索洛尔及其盐。

公开(公告)号：US20140079794A1

公开(公告)日：2014-03-20

申请号：US14027312

申请日：2013-09-16

Applicant: NITTO DENKO CORPORATION

Inventor： Chieko MIURA ,  Miki MAKABE ,  Eriko ABE ,  Shinji SUGAWARA ,  Toshiyuki YOSHIKAWA

IPC: A61K47/46

CPC classification number: A61K47/46 ,  A61K9/1658 ,  C08H1/06 ,  C08J3/247 ,  C08J2389/00 ,  Y10T428/2982

Abstract: The present invention relates to a gelatin particle, which is a thermally crosslinked non-porous spherical gelatin particle having a circularity of 0.8 or more and a dry particle diameter of 20 to 1,600 μm. The average volume swelling ratio of the gelatin particle in a case where the gelatin particle is immersed in physiological saline at 23° C. is from 200 to 2,000% relative to an average volume of the gelatin particle in a dried state. As for a swollen gelatin particle, it is preferable that the gelatin used has a jelly strength of 80 to 120 g and the swollen gelatin particle has a particle diameter of 50 to 2,000 μm. The gelatin particle can be used for blood vessel embolization and also for controlled release of physiologically active substance.

Abstract translation: 本发明涉及一种明胶颗粒，其是圆形度为0.8以上，干燥粒径为20〜1600μm的热交联无孔球状明胶粒子。 明胶颗粒在23℃下浸入生理盐水的情况下的明胶颗粒的平均体积溶胀比相对于干燥状态下的明胶颗粒的平均体积为200〜2000％。 对于溶胀的明胶粒子，优选使用的明胶的凝胶强度为80〜120g，膨胀的明胶粒子的粒径为50〜2000μm。 明胶颗粒可用于血管栓塞和用于控制释放生理活性物质。

公开(公告)号：US20220204813A1

公开(公告)日：2022-06-30

申请号：US17426017

申请日：2020-01-28

Applicant: NITTO DENKO CORPORATION

Inventor： Noboru YOSHIDA ,  Kiyoaki KODAMA ,  Eriko ABE ,  Ryuhei ARIMA

IPC: C09J7/26 ,  C09J7/38

Abstract: An adhesive skin patch including a substrate and an adhesive layer, wherein the substrate is formed of a foam sheet having breaking elongation of 100% or more, breaking strength of 20 N/20 mm or less, a density of 0.5 g/cm3 or less and a thickness of 0.300 mm or more, the adhesive layer is formed on one side of the substrate, and the adhesive layer contains an acrylic copolymer and a liquid or pasty component at room temperature.

公开(公告)号：US20220151836A1

公开(公告)日：2022-05-19

申请号：US17426011

申请日：2020-01-28

Applicant: NITTO DENKO CORPORATION

Inventor： Noboru YOSHIDA ,  Kiyoaki KODAMA ,  Eriko ABE ,  Ryuhei ARIMA

IPC: A61F13/02 ,  C09J7/26 ,  C09J133/10

Abstract: An adhesive skin patch including a substrate and an adhesive layer, wherein the substrate is formed of a foam sheet having open cells and a bubble fraction of 70% or more, and the adhesive layer is partially formed on one side of the substrate.