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公开(公告)号：US10925892B2
公开(公告)日：2021-02-23
申请号：US16281316
申请日：2019-02-21
Applicant: Novartis AG
Inventor： Howard Allen Ketelson , James W. Davis , Rekha Rangarajan
IPC: A61K31/736 , A61P27/02 , A61K9/00 , A61K9/107 , A61K47/14 , A61K47/24 , B01F17/00 , A61K47/02 , A61K47/10
Abstract: The present invention is directed to a lipid-based ophthalmic emulsion. The emulsion has an increased amount of a mucoadhesive galactomannan polymer that promotes a long-lasting protection against desiccation and moisture retention.
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公开(公告)号：US20170160565A1
公开(公告)日：2017-06-08
申请号：US15352171
申请日：2016-11-15
Applicant: Novartis AG
Inventor： Leroy Wainaina Muya , Howard Allen Ketelson
CPC classification number: G02C7/049 , A45C11/005 , A61L2/07 , A61L12/04 , B29D11/00067 , B65B5/04 , B65B25/008 , B65B55/06 , B65B55/14 , B65B55/22 , B65D81/22 , C08L33/14 , C08L39/06 , C08L2201/54 , C08L2203/02 , G02C2202/16
Abstract: The present invention relates to improved contact lens products which not only have an improved and sustainable wettability. The contact lens product of the invention comprises a soft hydrogel contact lens immersed and autoclaved in a packaging solution including a polyoxyethylene-polyoxybutylene block copolymer and a high molecular weight copolymer of N-vinylpyrrolidone and at least one amino-containing vinylic monomer. The present invention also provides methods for making contact lens products of the invention.
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公开(公告)号：US09591850B2
公开(公告)日：2017-03-14
申请号：US14496044
申请日：2014-09-25
Applicant: Novartis AG
Inventor： Leroy Wainaina Muya , Howard Allen Ketelson
CPC classification number: A01N25/30 , A01N59/00 , A61L12/128
Abstract: This invention relates generally to disinfection and cleaning systems for medical devices. In a preferred embodiment, the invention relates to compositions, methods and articles for simultaneously cleaning and disinfecting contact lenses. The present invention is directed to ophthalmic compositions containing one or more block copolymers referred to as (polyoxyethylene)-(poly-oxybutylene) block copolymers (“PEO-PBO”). The invention is particularly directed to the use of PEO-PBO di-block copolymers as non-foaming wetting agents in peroxide-based compositions for disinfecting contact lenses.
Abstract translation: 本发明一般涉及用于医疗装置的消毒和清洁系统。 在优选的实施方案中，本发明涉及用于同时清洁和消毒隐形眼镜的组合物，方法和制品。 本发明涉及含有一种或多种称为（聚氧乙烯） - （聚氧丁烯）嵌段共聚物（“PEO-PBO”）的嵌段共聚物的眼用组合物。 本发明特别涉及在基于过氧化物的组合物中使用PEO-PBO二嵌段共聚物作为消泡隐形眼镜的非泡沫润湿剂。
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公开(公告)号：US20180059436A1
公开(公告)日：2018-03-01
申请号：US15792808
申请日：2017-10-25
Applicant: Novartis AG
Inventor： Leroy Wainaina Muya , Howard Allen Ketelson
IPC: G02C7/04 , A45C11/00 , A61L2/07 , A61L12/04 , B29D11/00 , B65B5/04 , B65B25/00 , B65B55/06 , B65B55/14 , B65B55/22 , B65D81/22 , C08L33/14 , C08L39/06
CPC classification number: G02C7/049 , A45C11/005 , A61L2/07 , A61L12/04 , B29D11/00067 , B65B5/04 , B65B25/008 , B65B55/06 , B65B55/14 , B65B55/22 , B65D81/22 , C08L33/14 , C08L39/06 , C08L2201/54 , C08L2203/02 , G02C2202/16
Abstract: The present invention relates to improved contact lens products which not only have an improved and sustainable wettability. The contact lens product of the invention comprises a soft hydrogel contact lens immersed and autoclaved in a packaging solution including a polyoxyethylene-polyoxybutylene block copolymer and a high molecular weight copolymer of N-vinylpyrrolidone and at least one amino-containing vinylic monomer. The present invention also provides methods for making contact lens products of the invention.
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公开(公告)号：US09829723B2
公开(公告)日：2017-11-28
申请号：US15352171
申请日：2016-11-15
Applicant: Novartis AG
Inventor： Leroy Wainaina Muya , Howard Allen Ketelson
IPC: G02C7/00 , G02C7/02 , G02C7/04 , A45C11/00 , B65B5/04 , B65B55/06 , B65B55/14 , B65D81/22 , C08L33/14 , C08L39/06 , A61L2/07 , A61L12/04 , B29D11/00 , B65B25/00 , B65B55/22
CPC classification number: G02C7/049 , A45C11/005 , A61L2/07 , A61L12/04 , B29D11/00067 , B65B5/04 , B65B25/008 , B65B55/06 , B65B55/14 , B65B55/22 , B65D81/22 , C08L33/14 , C08L39/06 , C08L2201/54 , C08L2203/02 , G02C2202/16
Abstract: The present invention relates to improved contact lens products which not only have an improved and sustainable wettability. The contact lens product of the invention comprises a soft hydrogel contact lens immersed and autoclaved in a packaging solution including a polyoxyethylene-polyoxybutylene block copolymer and a high molecular weight copolymer of N-vinylpyrrolidone and at least one amino-containing vinylic monomer. The present invention also provides methods for making contact lens products of the invention.
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Patent Agency Ranking
公开(公告)号：US10151936B2
公开(公告)日：2018-12-11
申请号：US15792808
申请日：2017-10-25
Applicant: Novartis AG
Inventor： Leroy Wainaina Muya , Howard Allen Ketelson
IPC: G02C7/04 , A45C11/00 , B65B5/04 , B65B55/06 , B65B55/14 , B65D81/22 , C08L33/14 , C08L39/06 , A61L2/07 , A61L12/04 , B29D11/00 , B65B25/00 , B65B55/22
Abstract: The present invention relates to improved contact lens products which not only have an improved and sustainable wettability. The contact lens product of the invention comprises a soft hydrogel contact lens immersed and autoclaved in a packaging solution including a polyoxyethylene-polyoxybutylene block copolymer and a high molecular weight copolymer of N-vinylpyrrolidone and at least one amino-containing vinylic monomer. The present invention also provides methods for making contact lens products of the invention.
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公开(公告)号：US20170142964A1
公开(公告)日：2017-05-25
申请号：US15421835
申请日：2017-02-01
Applicant: Novartis AG
Inventor： Leroy Wainaina Muya , Howard Allen Ketelson
CPC classification number: A01N25/30 , A01N59/00 , A61L12/128
Abstract: This invention relates generally to disinfection and cleaning systems for medical devices. In a preferred embodiment, the invention relates to compositions, methods and articles for simultaneously cleaning and disinfecting contact lenses. The present invention is directed to ophthalmic compositions containing one or more block copolymers referred to as (polyoxyethylene)-(poly-oxybutylene) block copolymers (“PEO-PBO”). The invention is particularly directed to the use of PEO-PBO di-block copolymers as non-foaming wetting agents in peroxide-based compositions for disinfecting contact lenses.
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公开(公告)号：US20170136057A1
公开(公告)日：2017-05-18
申请号：US15421513
申请日：2017-02-01
Applicant: Novartis AG
Inventor： James W. Davis , Howard Allen Ketelson , Elaine E. Campbell , David L. Meadows , Rekha Rangarajan
IPC: A61K31/736 , A61K47/10 , A61K47/26 , A61K47/02 , A61K31/728 , A61K9/00
CPC classification number: A61K31/736 , A61K9/0048 , A61K31/728 , A61K47/02 , A61K47/10 , A61K47/26 , A61K47/32 , A61K47/36
Abstract: The present invention relates to artificial tear compositions and ophthalmic compositions suitable for drug delivery. In one embodiment of the present invention, the compositions comprise a galactomannan polymer such as guar or hydroxypropyl guar, hyaluronic acid, and a cis-diol such as sorbitol. In a preferred embodiment, the compositions also comprise a borate compound.
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公开(公告)号：US20150093452A1
公开(公告)日：2015-04-02
申请号：US14496044
申请日：2014-09-25
Applicant: NOVARTIS AG
Inventor： Leroy Wainaina Muya , Howard Allen Ketelson
CPC classification number: A01N25/30 , A01N59/00 , A61L12/128
Abstract: This invention relates generally to disinfection and cleaning systems for medical devices. In a preferred embodiment, the invention relates to compositions, methods and articles for simultaneously cleaning and disinfecting contact lenses. The present invention is directed to ophthalmic compositions containing one or more block copolymers referred to as (polyoxyethylene)-(poly-oxybutylene) block copolymers (“PEO-PBO”). The invention is particularly directed to the use of PEO-PBO di-block copolymers as non-foaming wetting agents in peroxide-based compositions for disinfecting contact lenses.
Abstract translation: 本发明一般涉及用于医疗装置的消毒和清洁系统。 在优选的实施方案中，本发明涉及用于同时清洁和消毒隐形眼镜的组合物，方法和制品。 本发明涉及含有一种或多种称为（聚氧乙烯） - （聚氧丁烯）嵌段共聚物（“PEO-PBO”）的嵌段共聚物的眼用组合物。 本发明特别涉及在基于过氧化物的组合物中使用PEO-PBO二嵌段共聚物作为消泡隐形眼镜的非泡沫润湿剂。
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公开(公告)号：US20190255096A1
公开(公告)日：2019-08-22
申请号：US16281316
申请日：2019-02-21
Applicant: Novartis AG
Inventor： Howard Allen Ketelson , James W. Davis , Rekha Rangarajan
Abstract: The present invention is directed to a lipid-based ophthalmic emulsion. The emulsion has an increased amount of a mucoadhesive galactomannan polymer that promotes a long-lasting protection against desiccation and moisture retention.
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