公开(公告)号：US11478754B2

公开(公告)日：2022-10-25

申请号：US16725183

申请日：2019-12-23

Applicant: National Research Council of Canada ,  The Royal Institution for the Advancement of Learning/McGill University

Inventor： Kebin Li ,  Teodor Veres ,  Tohid Fatanat Didar ,  Maryam Tabrizian

IPC: B01D63/08 ,  B01D69/10 ,  B01D65/02 ,  F04B43/04 ,  F04B43/12 ,  F04B53/10 ,  F04B43/14

Abstract: A technique for separating components of a microfluid, comprises a self-intersecting micro or nano-fluidic channel defining a cyclic path for circulating the fluid over a receiving surface of a fluid component separating member; and equipment for applying coordinated pressure to the channel at a plurality of pressure control areas along the cyclic path to circulate the fluid over the receiving surface, applying a pressure to encourage a desired transmission through the separating member, and a circulating pressure to remove surface obstructions on the separating member. The equipment preferably defines a peristaltic pump. Turbulent microfluidic flow appears to be produced.

公开(公告)号：US11867320B2

公开(公告)日：2024-01-09

申请号：US16970520

申请日：2019-03-04

Applicant: National Research Council of Canada

Inventor： Kebin Li ,  Keith Morton ,  Teodor Veres

IPC: F16K99/00 ,  B01L3/00

CPC classification number: F16K99/0025 ,  F16K99/0015 ,  B01L3/502738 ,  B01L2200/12 ,  B01L2300/123 ,  B01L2400/0487 ,  B01L2400/0655 ,  F16K99/0059 ,  F16K2099/0074 ,  F16K2099/0084

Abstract: In a polymeric microfluidic valve, an adhesion control surface with discrete micro- or nano-scale structured surfaces are separated by fluid filled voids at an interface between an elastomeric membrane seals against a substrate layer. The structured surfaces reduce adhesion between the membrane layer and the substrate layer and prevent permanent bonding, while at the same time providing a good balance of adhesion at the valve seat to provide a sealing engagement. Microstructured adhesion control surfaces on and around valve bodies permit opening the valve, by reducing contact surface area.

公开(公告)号：US10569225B2

公开(公告)日：2020-02-25

申请号：US14779446

申请日：2014-03-27

Applicant: National Research Council of Canada ,  The Royal Institution for the Advancement of Learning/McGill University

Inventor： Kebin Li ,  Teodor Veres ,  Tohid Fatanat Didar ,  Maryam Tabrizian

IPC: G01N1/10 ,  B01D63/08 ,  B01D69/10 ,  F04B43/04 ,  F04B43/14 ,  B01D65/02 ,  F04B43/12 ,  F04B53/10

Abstract: A technique for separating components of a microfluid, comprises a self-intersecting micro or nano-fluidic channel defining a cyclic path for circulating the fluid over a receiving surface of a fluid component separating member; and equipment for applying coordinated pressure to the channel at a plurality of pressure control areas along the cyclic path to circulate the fluid over the receiving surface, applying a pressure to encourage a desired transmission through the separating member, and a circulating pressure to remove surface obstructions on the separating member. The equipment preferably defines a peristaltic pump. Turbulent microfluidic flow appears to be produced.