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公开(公告)号：US20240324873A1
公开(公告)日：2024-10-03
申请号：US18621342
申请日：2024-03-29
Applicant: Optos plc
Inventor： Margaret Catherine Normand , Miguel Angel Preciado
CPC classification number: A61B3/102 , A61B3/1225 , G06T5/80 , G06T2207/10101 , G06T2207/30041
Abstract: A line-field Fourier-domain optical coherence tomography, OCT, imaging system, comprising: a curved mirror, and a scanning element at a first focus of the mirror which scans, via the mirror, a line of light across an object at a second focus of the mirror, and receives, via the mirror, light scattered by the object and aberrated by the mirror to form an aberrated line of light; a photodetector array; an interferometer which projects an interference line of light resulting from an interference between a reference light and the aberrated line of light onto the photodetector array. The OCT imaging system generates OCT data based on the interference line of light detected by the photodetector array, and corrects the OCT data using phase information in the OCT data such that the corrected OCT data has less optical aberration than the OCT data.
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公开(公告)号：US20220218196A1
公开(公告)日：2022-07-14
申请号：US17532501
申请日：2021-11-22
Applicant: OPTOS PLC
Inventor： Miguel Angel Preciado , Lijo Varughese Chacko
Abstract: An optical coherence tomography instrument suitable for imaging a retina is disclosed. In the instrument, an adjustable optical frequency shifter, which can be or include an acousto-optic modulator or electro-optic modulator, is arranged either (i) between a coupler and a reference optical system, (ii) in a reference optical system, (iii) between the coupler and a front-end optical system, or (iv) in a front-end optical system. The optical frequency of reference light or signal light may adjustably be increased or decreased. In operation, a subject is arranged such that its retina is in the focal depth of the front-end optical system. The increase or decrease in the optical frequency of the reference light or the sample light can be adjusted. Thereby, an interferogram representing a depth structure at the retina obtained between returning signal light and returning reference light may be brought to lie within a detection bandwidth of the instrument.
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公开(公告)号：US12070269B2
公开(公告)日：2024-08-27
申请号：US17532501
申请日：2021-11-22
Applicant: OPTOS PLC
Inventor： Miguel Angel Preciado , Lijo Varughese Chacko
IPC: A61B3/10 , G01B9/02091
CPC classification number: A61B3/102 , G01B9/02091
Abstract: An optical coherence tomography instrument suitable for imaging a retina is disclosed. In the instrument, an adjustable optical frequency shifter, which can be or include an acousto-optic modulator or electro-optic modulator, is arranged either (i) between a coupler and a reference optical system, (ii) in a reference optical system, (iii) between the coupler and a front-end optical system, or (iv) in a front-end optical system. The optical frequency of reference light or signal light may adjustably be increased or decreased. In operation, a subject is arranged such that its retina is in the focal depth of the front-end optical system. The increase or decrease in the optical frequency of the reference light or the sample light can be adjusted. Thereby, an interferogram representing a depth structure at the retina obtained between returning signal light and returning reference light may be brought to lie within a detection bandwidth of the instrument.
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Patent Agency Ranking
公开(公告)号：US20230363639A1
公开(公告)日：2023-11-16
申请号：US18197059
申请日：2023-05-13
Applicant: Optos PLC
Inventor： Miguel Angel Preciado
CPC classification number: A61B3/102 , A61B5/0066 , A61B3/0025
Abstract: A non-confocal point-scan Fourier-domain optical coherence tomography, OCT, imaging system, comprising: a scanning system arranged to perform a two-dimensional point scan of a light beam across an imaging target, and collect light scattered by the imaging target; a light detector arranged to generate a detection signal based on an interference between a reference light and the light collected by the scanning system. The OCT imaging system further comprises hardware arranged to: generate complex volumetric OCT data of the imaging target based on the detection signal, the OCT data including a component which, when the OCT data is processed to generate an enface projection of the OCT data, provides a defocusing and/or distortion in the enface projection; and generate corrected OCT data by executing a correction algorithm which uses phase information in the OCT data to remove at least some of the component from the OCT data.
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公开(公告)号：US11751765B2
公开(公告)日：2023-09-12
申请号：US17036201
申请日：2020-09-29
Applicant: Optos Plc
Inventor： Miguel Angel Preciado
CPC classification number: A61B3/156 , G02B26/02 , G02B26/0816 , G02B26/101 , G02F1/137 , A61B2090/306
Abstract: An ophthalmic device for imaging an eye, wherein a scanning element scans a first portion of light beam across a region of an eye via a light guiding component and a second portion of the light beam is reflected back by the light guiding component. The ophthalmic device further comprises: a light detector to detect light reflected from eye and guided to the light detector by the light guiding component; and a dynamic amplitude mask which receives the light reflected from the eye and the light reflected back by the light guiding component, and has an unmasked portion to allow light reflected from the eye to reach the light detector, and a masked portion whose spatial distribution varies with a scan angle such that the masked portion prevents light reflected back by the light guiding component from reaching the light detector during the scan.
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6.发明公开公开(公告)号：US20240197171A1
公开(公告)日：2024-06-20
申请号：US18527980
申请日：2023-12-04
Applicant: Optos plc
Inventor： Miguel Angel Preciado , Ewan Rycroft
IPC: A61B3/10 , G01B9/02 , G01B9/02055 , G01B9/02091 , G16H40/63
CPC classification number: A61B3/102 , G01B9/02043 , G01B9/02077 , G01B9/02091 , G16H40/63
Abstract: A Fourier-domain optical coherence tomography imaging system (10) comprising an Fourier-domain optical coherence tomography scanner (20) arranged to generate complex optical coherence tomography data (25) by performing a scan of an imaging target (30) to acquire samples whose complex values are indicative of an optical property of the imaging target at respective scan locations in the imaging target. The imaging system (10) further comprises a controller (40) arranged to calculate a two-dimensional cross-correlation using phase information of the acquired samples, and control the scanner (20), based on the calculated cross-correlation, to compensate for relative movement between the imaging target (30) and the scanner (20) during the scan.
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公开(公告)号：US20210348912A1
公开(公告)日：2021-11-11
申请号：US17233672
申请日：2021-04-19
Applicant: OPTOS PLC
Inventor： Miguel Angel Preciado , Lijo Varughese Chacko
Abstract: A swept-source OCT imaging system for imaging a region of an object, comprising: a swept light source which generates a beam of varying wavelength; a scanning element which scans the beam across the object; an interferometer which generates interference light by combining light scattered by the object (owing to the scan) with reference light; a photodetector which generates an electrical signal (S) having frequency components spanning a frequency band and caused by interference of the scattered light with the reference light; a band-pass filter module which band-pass filters the electrical signal; and a sample acquisition module which samples the filtered electrical signal. The band-pass filter module extracts at least some of the frequency components spanning the frequency band from the electrical signal. The sample acquisition module band-pass samples the filtered electrical signal.
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公开(公告)号：US20210093195A1
公开(公告)日：2021-04-01
申请号：US17036201
申请日：2020-09-29
Applicant: Optos Plc
Inventor： Miguel Angel Preciado
Abstract: An ophthalmic device for imaging an eye, wherein a scanning element scans a first portion of light beam across a region of an eye via a light guiding component and a second portion of the light beam is reflected back by the light guiding component. The ophthalmic device further comprises: a light detector to detect light reflected from eye and guided to the light detector by the light guiding component; and a dynamic amplitude mask which receives the light reflected from the eye and the light reflected back by the light guiding component, and has an unmasked portion to allow light reflected from the eye to reach the light detector, and a masked portion whose spatial distribution varies with a scan angle such that the masked portion prevents light reflected back by the light guiding component from reaching the light detector during the scan.
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