公开(公告)号：US20210040045A1

公开(公告)日：2021-02-11

申请号：US16886622

申请日：2020-05-28

Applicant: Pfizer Inc.

Inventor： Elaine GREER ,  Stephen ANDERSON ,  Mark MALONEY ,  Shu YU ,  Ekaterina ALBERT ,  Emily RIGSBEE

IPC: C07D233/88

Abstract: The present disclosure relates to: a) solid state forms of hydrobromide salts of Compound 1; b) pharmaceutical compositions comprising one or more solid state forms of hydrobromide salts of Compound 1, and, optionally, a pharmaceutically acceptable carrier; c) methods of treating tumors or cancers by administering one or more solid state forms of hydrobromide salts of Compound 1 to a subject in need thereof; and d) methods for the preparation of solid state forms of Compound 1.

公开(公告)号：US20230382872A1

公开(公告)日：2023-11-30

申请号：US18361545

申请日：2023-07-28

Applicant: Pfizer Inc.

Inventor： Elaine GREER ,  Stephen ANDERSON ,  Mark MALONEY ,  Shu YU ,  Ekaterina ALBERT ,  Emily RIGSBEE

IPC: C07D233/88

CPC classification number: C07D233/88 ,  C07B2200/13 ,  A61K31/40

Abstract: The present disclosure relates to: a) solid state forms of hydrobromide salts of Compound 1; b) pharmaceutical compositions comprising one or more solid state forms of hydrobromide salts of Compound 1, and, optionally, a pharmaceutically acceptable carrier; c) methods of treating tumors or cancers by administering one or more solid state forms of hydrobromide salts of Compound 1 to a subject in need thereof; and d) methods for the preparation of solid state forms of Compound 1.

公开(公告)号：US20240051924A1

公开(公告)日：2024-02-15

申请号：US18361472

申请日：2023-07-28

Applicant: Pfizer Inc.

Inventor： Elaine GREER ,  Stephen ANDERSON ,  Mark MALONEY ,  Shu YU ,  Ekaterina ALBERT ,  Emily RIGSBEE

IPC: C07D233/88

CPC classification number: C07D233/88 ,  C07B2200/13 ,  A61K31/40

Abstract: The present disclosure relates to: a) solid state forms of hydrobromide salts of Compound 1; b) pharmaceutical compositions comprising one or more solid state forms of hydrobromide salts of Compound 1, and, optionally, a pharmaceutically acceptable carrier; c) methods of treating tumors or cancers by administering one or more solid state forms of hydrobromide salts of Compound 1 to a subject in need thereof; and d) methods for the preparation of solid state forms of Compound 1.

公开(公告)号：US20240150299A1

公开(公告)日：2024-05-09

申请号：US18414019

申请日：2024-01-16

Applicant: PFIZER INC.

Inventor： Elaine GREER ,  Stephen ANDERSON ,  Mark MALONEY ,  Shu YU ,  Ekaterina ALBERT ,  Emily RIGSBEE

IPC: C07D233/88

CPC classification number: C07D233/88 ,  A61K31/40 ,  C07B2200/13

Abstract: The present disclosure relates to: a) solid state forms of hydrobromide salts of Compound 1; b) pharmaceutical compositions comprising one or more solid state forms of hydrobromide salts of Compound 1, and, optionally, a pharmaceutically acceptable carrier; c) methods of treating tumors or cancers by administering one or more solid state forms of hydrobromide salts of Compound 1 to a subject in need thereof; and d) methods for the preparation of solid state forms of Compound 1.

公开(公告)号：US20230167069A1

公开(公告)日：2023-06-01

申请号：US18160442

申请日：2023-01-27

Applicant: Pfizer Inc.

Inventor： Elaine GREER ,  Stephen ANDERSON ,  Mark MALONEY ,  Shu YU ,  Ekaterina ALBERT ,  Emily RIGSBEE

IPC: C07D233/88

CPC classification number: C07D233/88 ,  C07B2200/13 ,  A61K31/40

Abstract: The present disclosure relates to: a) solid state forms of hydrobromide salts of Compound 1; b) pharmaceutical compositions comprising one or more solid state forms of hydrobromide salts of Compound 1, and, optionally, a pharmaceutically acceptable carrier; c) methods of treating tumors or cancers by administering one or more solid state forms of hydrobromide salts of Compound 1 to a subject in need thereof; and d) methods for the preparation of solid state forms of Compound 1.

公开(公告)号：US20230406827A1

公开(公告)日：2023-12-21

申请号：US18157592

申请日：2023-01-20

Applicant: Pfizer Inc.

Inventor： Elaine GREER ,  Stephen ANDERSON ,  Mark MALONEY ,  Shu YU ,  Ekaterina ALBERT ,  Emily RIGSBEE

IPC: C07D233/88

CPC classification number: C07D233/88 ,  C07B2200/13 ,  A61K31/40

Abstract: The present disclosure relates to: a) solid state forms of hydrobromide salts of Compound 1; b) pharmaceutical compositions comprising one or more solid state forms of hydrobromide salts of Compound 1, and, optionally, a pharmaceutically acceptable carrier; c) methods of treating tumors or cancers by administering one or more solid state forms of hydrobromide salts of Compound 1 to a subject in need thereof; and d) methods for the preparation of solid state forms of Compound 1.

公开(公告)号：US20230202987A1

公开(公告)日：2023-06-29

申请号：US18170884

申请日：2023-02-17

Applicant: Pfizer Inc.

Inventor： Elaine GREER ,  Stephen ANDERSON ,  Mark MALONEY ,  Shu YU ,  Ekaterina ALBERT ,  Emily RIGSBEE

IPC: C07D233/88

CPC classification number: C07D233/88 ,  A61K31/40 ,  C07B2200/13

Abstract: The present disclosure relates to: a) solid state forms of hydrobromide salts of Compound 1; b) pharmaceutical compositions comprising one or more solid state forms of hydrobromide salts of Compound 1, and, optionally, a pharmaceutically acceptable carrier; c) methods of treating tumors or cancers by administering one or more solid state forms of hydrobromide salts of Compound 1 to a subject in need thereof; and d) methods for the preparation of solid state forms of Compound 1.