公开(公告)号：US20250163168A1

公开(公告)日：2025-05-22

申请号：US18947069

申请日：2024-11-14

Applicant: PFIZER INC.

Inventor： James Reasoner APGAR ,  Robert Gregory DULLEA ,  Jean-Philippe FORTIN ,  Allison Nicole LAU ,  Laura LIN LOHSE ,  Weixu MENG ,  Lidia MOSYAK

IPC: C07K16/28 ,  A61K39/00 ,  A61P3/04

Abstract: Disclosed herein are novel antibodies, novel agonist peptides, and novel dual agonist peptides. Further disclosed herein are novel antibody conjugates comprising the novel antibodies, novel agonist peptides, and/or novel dual agonist peptides disclosed herein. In some embodiments, the antibodies or antibody conjugates of the invention may be used to treat metabolic diseases.