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1.
公开(公告)号:US20240058416A1
公开(公告)日:2024-02-22
申请号:US18499534
申请日:2023-11-01
Applicant: Purdue Research Foundation
Inventor: Yoon Yeo , Simseok Yuk
CPC classification number: A61K38/1709 , A61K9/5123 , A61K31/7032 , A61K33/26 , A61K38/12 , A61K47/10 , A61K47/36 , A61P37/00
Abstract: The present invention generally relates to a process of nanoparticle formulations and its composition matter for systemic treatment of sepsis. In particular, this invention discloses a method for preparing tannic acid-ferric nanoparticles, optionally incorporating a component of vitamin D3, coated with zwitterionic chitosan (ZWC) and polymyxin B (PMB). The invention described herein also pertains to pharmaceutical compositions and methods for the treatment of sepsis.
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2.
公开(公告)号:US11865158B2
公开(公告)日:2024-01-09
申请号:US17636453
申请日:2020-08-21
Applicant: PURDUE RESEARCH FOUNDATION
Inventor: Yoon Yeo , Simseok Yuk
CPC classification number: A61K38/1709 , A61K9/5123 , A61K31/7032 , A61K33/26 , A61K38/12 , A61K47/10 , A61K47/36 , A61P37/00
Abstract: The present invention generally relates to a process of nanoparticle formulations and its composition matter for systemic treatment of sepsis. In particular, this invention discloses a method for preparing tannic acid-ferric nanoparticles, optionally incorporating a component of vitamin D3, coated with zwitterionic chitosan (ZWC) and polymyxin B (PMB). The invention described herein also pertains to pharmaceutical compositions and methods for the treatment of sepsis.
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