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公开(公告)号：US07723074B2
公开(公告)日：2010-05-25
申请号：US12348990
申请日：2009-01-06
Applicant: Ashfaq Parkar , Paul August , Theresa Kuntzweiler , Mohamad Ali Ardati , Namadev Baskaran
Inventor： Ashfaq Parkar , Paul August , Theresa Kuntzweiler , Mohamad Ali Ardati , Namadev Baskaran
IPC: C12P21/06 , C12N1/20 , C12N1/00 , C12N15/00 , C12N5/00 , C12N5/02 , C12N5/07 , C12N5/10 , C12N15/74 , C07H21/04
CPC classification number: C07K14/72 , C07K14/723 , C07K2319/00
Abstract: Described herein is a novel member of the prostanoid receptor family, a guinea pig prostaglandin D2 receptor. Described are the receptor, the nucleic acid that encodes it, and various uses for both.
Abstract translation: 本文描述的是前列腺素受体家族的新成员，豚鼠前列腺素D2受体。 描述的是受体，编码它的核酸，以及两者的各种用途。
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2.发明申请Nucleic acid encoding a novel prostaglandin receptor protein and methods of use thereof 有权编码新型前列腺素受体蛋白的核酸及其使用方法公开(公告)号：US20050142558A1
公开(公告)日：2005-06-30
申请号：US10747994
申请日：2003-12-30
Applicant: Ashfaq Parkar , Paul August , Theresa Kuntzweiler , Mohamad Ardati , Namadev Baskaran
Inventor： Ashfaq Parkar , Paul August , Theresa Kuntzweiler , Mohamad Ardati , Namadev Baskaran
IPC: C07K14/72 , C12Q1/68 , C07H21/04 , C07K14/705 , C07K16/28
CPC classification number: C07K14/72 , C07K14/723 , C07K2319/00
Abstract: Described herein is a novel member of the prostanoid receptor family, a guinea pig prostaglandin D2 receptor. Described are the receptor, the nucleic acid that encodes it, and various uses for both.
Abstract translation: 本文描述的是前列腺素受体家族的新成员，豚鼠前列腺素D2受体。 描述的是受体，编码它的核酸，以及两者的各种用途。
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3.发明授权Internal combustion engine with one or more compression caps between piston and cylinder head and deflection means in the combustion chamber through which rotary flow is induced in the charge 失效具有在活塞和气缸盖之间具有一个或多个压缩盖的内燃机和在燃烧室中的偏转装置，通过该燃烧室中的旋转流被引入
公开(公告)号：US4565181A
公开(公告)日：1986-01-21
申请号：US110935
申请日：1980-01-10
Applicant: Paul August
Inventor： Paul August
CPC classification number: F02B23/08 , Y02T10/125
Abstract: Internal combustion engine with one or more compression gap zones between piston and cylinder head at each side of a reduced size combustion chamber, and deflection means in the combustion chamber through which unidirectional rotary flow is induced in the fuel charge.
Abstract translation: 具有在减小尺寸的燃烧室的每一侧的活塞和气缸盖之间的一个或多个压缩间隙区域的内燃机，以及燃料室中的在燃料装料中引起单向旋转流的偏转装置。
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4.发明授权
公开(公告)号：US3977374A
公开(公告)日：1976-08-31
申请号：US249632
申请日：1972-05-02
Applicant: Paul August
Inventor： Paul August
CPC classification number: F02D21/08 , F02M29/00 , F02M61/04 , Y10S261/78
Abstract: An arrangement for the preparation of the fuel-intake air mixture for an internal combustion engine includes an idle fuel nozzle located in the engine induction manifold. Additional fuel nozzles, located in the intake air passage, are operable to supply fuel during other portions of the operating range. The fuel air mixtures formed by the arrangement are passed at speeds approaching sonic velocity to obtain a highly desirable mixing thereof.
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公开(公告)号：US20090226894A1
公开(公告)日：2009-09-10
申请号：US11721103
申请日：2005-12-01
Applicant: Dorre Grueneberg , Xi Huang , Sridaran Natesan , Paul August
Inventor： Dorre Grueneberg , Xi Huang , Sridaran Natesan , Paul August
IPC: C12Q1/68
CPC classification number: C12Q1/6886 , C12Q2600/106 , C12Q2600/158 , C12Q2600/178 , G01N33/574 , G01N33/6893
Abstract: The present invention relates to novel and useful methods that predict or monitor a patient's response to a molecule of the taxoid family by measuring the increase or decrease of specific genetic markers as compared to controls. The present invention also provides kits that predict of monitor patient's response to a molecule of the taxoid family by measuring nucleid acid or protein levels of particular genetic markers and comparing their levels to controls or reference markers.
Abstract translation: 本发明涉及通过与对照相比测量特定遗传标记物的增加或减少来预测或监测患者对紫杉类家族分子的反应的新颖和有用的方法。 本发明还提供了通过测量特定遗传标记的核酸或蛋白质水平并将其水平与对照或参考标记进行比较来预测监测患者对紫杉烷类分子的反应的试剂盒。
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Patent Agency Ranking
公开(公告)号：US07488799B2
公开(公告)日：2009-02-10
申请号：US11621164
申请日：2007-01-09
Applicant: Ashfaq Parkar , Paul August , Theresa Kuntzweiler , Mohamad Ali Ardati , Namadev Baskaran
Inventor： Ashfaq Parkar , Paul August , Theresa Kuntzweiler , Mohamad Ali Ardati , Namadev Baskaran
CPC classification number: C07K14/72 , C07K14/723 , C07K2319/00
Abstract: Described herein is a novel member of the prostanoid receptor family, a guinea pig prostaglandin D2 receptor. Described are the receptor, the nucleic acid that encodes it, and various uses for both.
Abstract translation: 本文描述的是前列腺素受体家族的新成员，豚鼠前列腺素D2受体。 描述的是受体，编码它的核酸，以及两者的各种用途。
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公开(公告)号：US08329669B2
公开(公告)日：2012-12-11
申请号：US12304818
申请日：2007-07-25
Applicant: Paul August , Waan Jeng Huang , Sridaran Natesan , Soyan Lieberman
Inventor： Paul August , Waan Jeng Huang , Sridaran Natesan , Soyan Lieberman
CPC classification number: A61K31/7105 , A61K9/0019 , A61K48/00 , C12N9/0055 , C12N15/1136 , C12N15/1137 , C12N2310/14 , C12N2799/027 , C12Y110/02002
Abstract: The present invention relates to a composition which is useful in the treatment of a tumor, a method for making such a composition, and a method for using such a composition. The invention relates also to a method for assaying for inhibitors of the activity of Core 1 protein and/or other proteins of the respiratory complex III of mitochondria.
Abstract translation: 本发明涉及一种可用于治疗肿瘤的组合物，该组合物的制备方法和使用该组合物的方法。 本发明还涉及用于测定线粒体呼吸复合物III的核心蛋白1和/或其它蛋白质的活性抑制剂的方法。
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公开(公告)号：US07183062B2
公开(公告)日：2007-02-27
申请号：US10747994
申请日：2003-12-30
Applicant: Ashfaq Parkar , Paul August , Theresa Kuntzweiler , Mohamad Ali Ardati , Namadev Baskaran
Inventor： Ashfaq Parkar , Paul August , Theresa Kuntzweiler , Mohamad Ali Ardati , Namadev Baskaran
IPC: G01N33/53 , G01N33/567 , C07K1/00 , C07K14/00 , C07K17/00
CPC classification number: C07K14/72 , C07K14/723 , C07K2319/00
Abstract: Described herein is a novel member of the prostanoid receptor family, a guinea pig prostaglandin D2 receptor. Described are the receptor, the nucleic acid that encodes it, and various uses for both.
Abstract translation: 本文描述的是前列腺素受体家族的新成员，豚鼠前列腺素D2受体。 描述的是受体，编码它的核酸，以及两者的各种用途。
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9.发明授权
公开(公告)号：US4751902A
公开(公告)日：1988-06-21
申请号：US844924
申请日：1986-03-17
Applicant: Paul August
Inventor： Paul August
CPC classification number: F02B17/00 , F02B23/08 , F02F1/4214 , F02B1/04 , F02F2001/247 , Y02T10/125 , Y02T10/146
Abstract: The procedure for the introduction of a layer charge for Otto motors uses a richer mixture in the area of the spark plug and a correspondingly weaker for the remaining areas. The rich mixture is led under pressure through "squish" spaces to the spark plug, in which, in one embodiment, at least one flow vortex accelerated at medium power by the type and shape of the combustion chamber together with the position of the "squish" spaces is created. In this way a very low fuel consumption at minimal carbon monoxide, hydrocarbon and nitrogen content of the exhaust gas is achieved. The motor can be driven at a total mixture composition of Lambda 1.5 or more, in which a readily ignitable mixture of Lambda 0.8 to 1.0 is injected into in the area of the spark plug.
Abstract translation: 为奥托电机引入层电荷的步骤在火花塞区域使用更丰富的混合物，对于其余区域相对较弱。 丰富的混合物在压力下通过“挤压”的空间被引导到火花塞，其中在一个实施例中，通过燃烧室的类型和形状加上中等功率的至少一个流涡流与“挤压” “空格被创建。 以这种方式实现了废气中一氧化碳，烃和氮含量最低的燃料消耗。 电动机可以以1.5或更大的混合物组合物进行驱动，其中Lambda 0.8至1.0的容易点燃的混合物被注入到火花塞的区域中。
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公开(公告)号：US20100035807A1
公开(公告)日：2010-02-11
申请号：US12304818
申请日：2007-07-25
Applicant: Paul August , Waan Jeng Huang , Sridaran Natesan , Soyan Lieberman
Inventor： Paul August , Waan Jeng Huang , Sridaran Natesan , Soyan Lieberman
IPC: A61K38/19 , A61K31/7088 , G01N33/53 , A61P35/00
CPC classification number: A61K31/7105 , A61K9/0019 , A61K48/00 , C12N9/0055 , C12N15/1136 , C12N15/1137 , C12N2310/14 , C12N2799/027 , C12Y110/02002
Abstract: The present invention relates to a composition which is useful in the treatment of a tumor, a method for making such a composition, and a method for using such a composition. The invention relates also to a method for assaying for inhibitors of the activity of Core 1 protein and/or other proteins of the respiratory complex III of mitochondria.
Abstract translation: 本发明涉及一种可用于治疗肿瘤的组合物，该组合物的制备方法和使用该组合物的方法。 本发明还涉及用于测定线粒体呼吸复合物III的核心蛋白1和/或其它蛋白质的活性抑制剂的方法。
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