公开(公告)号：US20240245811A1

公开(公告)日：2024-07-25

申请号：US18040021

申请日：2021-07-30

Applicant: Paul Scherrer Institut

Inventor： Michal Grzmil ,  Roger Schibli ,  Martin Behe ,  Alain Blanc ,  Yun Qin

IPC: A61K51/08 ,  A61P35/00 ,  C07K7/08

CPC classification number: A61K51/088 ,  A61P35/00 ,  C07K7/08

Abstract: An alpha radiolabeled gastrin analogue is used in peptide receptor radionuclide therapy (PRRT) applications. In particular, an alpha radiolabeled gastrin analogue, which exhibits excellent biodistribution and therapeutic efficacy while toxicity for healthy tissues is prevented and/or reduced. The alpha radiolabeled gastrin analogue is used in methods of treating cholecystokinin (CCKB) receptor positive diseases.