公开(公告)号：US20250051246A1

公开(公告)日：2025-02-13

申请号：US18799069

申请日：2024-08-09

Applicant: Pfizer Inc.

Inventor： Karen Jean COFFMAN ,  Dafydd Rhys OWEN ,  Matthew Richard REESE ,  Matthew Forrest SAMMONS ,  Raman SHARMA ,  Jamison Bryce TUTTLE ,  Qingyi YANG

IPC: C07B59/00 ,  A61K31/4025 ,  A61P31/14 ,  C07D403/12

Abstract: The invention relates to compounds of Formula (I) wherein Y1a, Y1b, Y2a, Y2b, Y2c, Y2d, Y2e, Y2f, Y2g, Y2h and Y2i are as defined herein and to their use in medicine; to compositions containing them; to processes for their preparation; and to intermediates used in such processes. The compounds of Formula (I) may be useful in the treatment of coronavirus infections and coronavirus infection related disorders.