公开(公告)号：US20230390307A1

公开(公告)日：2023-12-07

申请号：US18249581

申请日：2021-10-19

Applicant: Pfizer Inc.

Inventor： Omar Abdelrahman Salman ,  Joel Aaron Bergman

IPC: A61K31/573 ,  A61K47/22 ,  A61K31/57 ,  A61K9/10

CPC classification number: A61K31/573 ,  A61K47/22 ,  A61K31/57 ,  A61K9/10

Abstract: A parenteral aqueous suspension formulation for corticosteroids without polyethylene glycol (PEG) or Polysorbate (PS) that has better resuspendability, longer stability compared to commercially available formulations, and additionally allows for stable formulations of higher concentrations of corticosteroids that were not previously feasible. Preferably, the corticosteroid is methylprednisolone acetate or medroxyprogesterone acetate.