公开(公告)号：US20240238214A1

公开(公告)日：2024-07-18

申请号：US18580977

申请日：2022-07-20

Applicant: Purdue Research Foundation

Inventor： Yoon Yeo ,  Soonbum Kwon

IPC: A61K9/51 ,  A61K31/337 ,  A61K38/07 ,  A61K39/395 ,  A61P35/00

CPC classification number: A61K9/5146 ,  A61K9/5123 ,  A61K9/5169 ,  A61K31/337 ,  A61K38/07 ,  A61K39/3955 ,  A61P35/00

Abstract: Nanoconstructs and compositions comprising a nanoparticle coated with an immunoadjuvant (e.g. ATP) and comprising one or more therapeutic agents (e.g. ICD inducer) encapsulated therein; and methods for treating cancer in a subject using such nanoconstructs and compositions, as well as combination immunotherapies.