公开(公告)号：US12257217B2

公开(公告)日：2025-03-25

申请号：US18046919

申请日：2022-10-15

Applicant: Purdue Research Foundation

Inventor： Kee-Hong Kim ,  Yuyan Zhu

IPC: A61K31/18 ,  A61K31/167 ,  A61P3/04 ,  A61P3/06 ,  A61P3/10 ,  C12N15/113

Abstract: A composition comprising an active agent that inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT) is provided. With the composition, food intake can be suppressed, and/or body weight can be reduced, and/or metabolic disorders can be prevented and/or treated.

公开(公告)号：US20210299073A1

公开(公告)日：2021-09-30

申请号：US17343589

申请日：2021-06-09

Applicant: Purdue Research Foundation

Inventor： Kee-Hong KIM ,  Yuyan Zhu

IPC: A61K31/18 ,  A61P3/04 ,  A61K31/167 ,  C12N15/113

Abstract: A composition comprising an active agent that inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT) is provided. With the composition, food intake can be suppressed, and/or body weight can be reduced, and/or metabolic disorders can be prevented and/or treated.

公开(公告)号：US12274681B2

公开(公告)日：2025-04-15

申请号：US18046916

申请日：2022-10-15

Applicant: Purdue Research Foundation

Inventor： Kee-Hong Kim ,  Yuyan Zhu

IPC: A61K31/18 ,  A61K31/167 ,  A61P3/04 ,  A61P3/06 ,  A61P3/10 ,  C12N15/113

Abstract: A composition comprising an active agent that inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT) is provided. With the composition, food intake can be suppressed, and/or body weight can be reduced, and/or metabolic disorders can be prevented and/or treated.

公开(公告)号：US11872198B2

公开(公告)日：2024-01-16

申请号：US17343589

申请日：2021-06-09

Applicant: Purdue Research Foundation

Inventor： Kee-Hong Kim ,  Yuyan Zhu

IPC: A61K31/18 ,  A61P3/04 ,  A61K31/167 ,  C12N15/113 ,  A61P3/10 ,  A61P3/06

CPC classification number: A61K31/18 ,  A61K31/167 ,  A61P3/04 ,  A61P3/10 ,  C12N15/1137 ,  A61P3/06 ,  C12N2310/14 ,  C12N2310/531

Abstract: A composition comprising an active agent that inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT) is provided. With the composition, food intake can be suppressed, and/or body weight can be reduced, and/or metabolic disorders can be prevented and/or treated.

公开(公告)号：US12274682B2

公开(公告)日：2025-04-15

申请号：US18046917

申请日：2022-10-15

Applicant: Purdue Research Foundation

Inventor： Kee-Hong Kim ,  Yuyan Zhu

IPC: A61K31/18 ,  A61K31/167 ,  A61P3/04 ,  A61P3/06 ,  A61P3/10 ,  C12N15/113

Abstract: A composition comprising an active agent that inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT) is provided. With the composition, food intake can be suppressed, and/or body weight can be reduced, and/or metabolic disorders can be prevented and/or treated.

公开(公告)号：US11065216B2

公开(公告)日：2021-07-20

申请号：US16461597

申请日：2017-11-16

Applicant: Purdue Research Foundation

Inventor： Kee-Hong Kim ,  Yuyan Zhu

IPC: A61K31/18 ,  A61P3/04 ,  A61K31/167 ,  C12N15/113

Abstract: A composition comprising an active agent that inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT) is provided. With the composition, food intake can be suppressed, and/or body weight can be reduced, and/or metabolic disorders can be prevented and/or treated.