公开(公告)号：US20230173407A1

公开(公告)日：2023-06-08

申请号：US17996777

申请日：2021-04-27

Applicant: Puridify Ltd

Inventor： Matthew Townsend ,  Ian Scanlon ,  Ola Lind ,  Gunnar Malmquist

IPC: B01D15/18 ,  B01D15/20 ,  B01D15/42 ,  B01D15/24

CPC classification number: B01D15/1885 ,  B01D15/203 ,  B01D15/424 ,  B01D15/247

Abstract: The present invention relates to a preparative chromatography system (200, 500, 800) and a chromatography process (400, 700) adapted to repetitive cycling of chromatography volumes. The system (200, 500, 800) comprises at least two upstream pumps (203a, 803a, 203b, 803b) and separate flow paths (220) from process liquid sources to the chromatography device (200, 500, 800). The system (200, 500, 800) is arranged to prime one flow path (220) with one process liquid while providing another process liquid to the chromatography device and thereby minimizing the hold-up volume of the system (200, 500, 800).