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公开(公告)号:US20250035622A1
公开(公告)日:2025-01-30
申请号:US18763140
申请日:2024-07-03
Inventor: Kabir H. Biswas , Asma Fatima , Anupriya M. Geethakumari
IPC: G01N33/543 , G01N33/569
Abstract: A biosensor for detecting proteolytic cleavage activity of two proteases, coronavirus main protease (Mpro) and papain-like protease (PLpro) is provided. The biosensor utilizes Bioluminescence Resonance Energy Transfer (BRET) between a donor and two acceptor moieties.