公开(公告)号：US20220105183A1

公开(公告)日：2022-04-07

申请号：US17296166

申请日：2019-11-14

Applicant: Qingdao University of Science and Technology

Inventor： Xianfeng ZHOU ,  Zhibo LI ,  Xueluer MU

IPC: A61K41/00 ,  A61K49/22 ,  A61P35/00 ,  C07D209/10 ,  C07D405/08

Abstract: A micro-nano structure formed by self-assembling a compound represented by formula (I), an isomer thereof, a pharmaceutically acceptable salt, a hydrate or a solvate in an aqueous solution, a preparation method for the micro-nano structure, and use thereof are described. The micro-nano structure has the advantages of having high photothermal conversion efficiency, good photothermal stability, good photothermal effect and photodynamic effect, being easily degraded, and having high safety, and can be passively targeted to tumor sites, having a broad prospect in the diagnosis and treatment of cancers and skin diseases.