公开(公告)号：US20150276589A1

公开(公告)日：2015-10-01

申请号：US14693301

申请日：2015-04-22

Applicant: Redshift Systems Corporation

Inventor： Matthias Wagner ,  Charles McAlister Marshall ,  Donald Kuehl ,  Jeffrey Guasto

IPC: G01N21/39 ,  G01N21/03 ,  G01N21/3577 ,  G01N21/05

CPC classification number: G01N15/1436 ,  G01N15/0205 ,  G01N15/1404 ,  G01N15/1484 ,  G01N21/0332 ,  G01N21/05 ,  G01N21/3577 ,  G01N21/39 ,  G01N21/532 ,  G01N21/85 ,  G01N2021/399 ,  G01N2201/0612 ,  G01N2201/10

Abstract: A fluid analyzer includes an optical source and an optical detector defining an optical beam path through an interrogation region of a fluid flow cell. Motion control devices determine position of the interrogation region. Flow-control devices conduct analyte and reference fluids and manipulate fluid flow in response to control signals to position a fluid boundary across the interrogation region. A controller (1) generates a time-varying motion modulation signal to move the interrogation region across the fluid boundary, (2) samples an output signal from the optical detector at one time in which the interrogation region contains more analyte fluid than reference fluid and at a time at which the interrogation region contains more reference fluid than analyte fluid, thereby generating corresponding output signal samples, and (3) determines from the output signal samples a measurement value indicative of an optically measured characteristic of the analyte fluid.

Abstract translation: 流体分析器包括光源和光学检测器，其限定穿过流体流动池的询问区域的光束路径。 运动控制装置确定询问区域的位置。 流量控制装置进行分析物和参考流体，并响应于控制信号操纵流体流动，以便在询问区域上定位流体边界。 控制器（1）产生时变运动调制信号，以移动询问区域跨过流体边界，（2）在询问区域中包含比参考流体多的分析物流体的一次的时间对来自光学检测器的输出信号进行采样;以及 在询问区域包含比分析物流体更多的参考流体的时间，从而产生相应的输出信号样本，以及（3）从输出信号样本确定指示分析物流体的光学测量特性的测量值。

公开(公告)号：US20170030823A1

公开(公告)日：2017-02-02

申请号：US15175709

申请日：2016-06-07

Applicant: Redshift Systems Corporation

Inventor： Matthias Wagner ,  Charles McAllister Marshall ,  Donald Kuehl ,  Jeffrey Guasto

IPC: G01N15/14 ,  G01N21/05 ,  G01N21/53 ,  G01N21/85 ,  G01N15/02 ,  G01N21/39 ,  G01N21/3577

CPC classification number: G01N15/1436 ,  G01N15/0205 ,  G01N15/1404 ,  G01N15/1484 ,  G01N21/0332 ,  G01N21/05 ,  G01N21/3577 ,  G01N21/39 ,  G01N21/532 ,  G01N21/85 ,  G01N2021/399 ,  G01N2201/0612 ,  G01N2201/10

Abstract: A fluid analyzer includes an optical source and detector defining a beam path of an optical beam, and a fluid flow cell on the beam path defining an interrogation region in a fluid channel in which the optical beam interacts with fluids. One or more flow-control devices conduct a particle in a fluid through the fluid channel. A motion system moves the interrogation region relative to the fluid channel in response to a motion signal, and a controller (1) generates the motion signal having a time-varying characteristic, (2) samples an output signal from the optical detector at respective intervals of the motion signal during which the interrogation region contains and does not contain the particle, and (3) determines from output signal samples a measurement value indicative of an optically measured characteristic of the particle.

Abstract translation: 流体分析器包括限定光束的光束路径的光源和检测器，以及光束路径上的流体流动池，其限定了光束与流体相互作用的流体通道中的询问区域。 一个或多个流量控制装置通过流体通道传导流体中的颗粒。 运动系统响应于运动信号移动询问区域相对于流体通道，并且控制器（1）产生具有时变特性的运动信号，（2）以相应的间隔对来自光学检测器的输出信号进行采样 其中询问区域包含并且不包含颗粒的运动信号，以及（3）从输出信号样本确定指示颗粒的光学测量特性的测量值。

公开(公告)号：US09377400B2

公开(公告)日：2016-06-28

申请号：US14693301

申请日：2015-04-22

Applicant: Redshift Systems Corporation

Inventor： Matthias Wagner ,  Charles McAlister Marshall ,  Donald Kuehl ,  Jeffrey Guasto

IPC: G01N21/00 ,  G01N21/39 ,  G01N21/05 ,  G01N21/03 ,  G01N21/3577

CPC classification number: G01N15/1436 ,  G01N15/0205 ,  G01N15/1404 ,  G01N15/1484 ,  G01N21/0332 ,  G01N21/05 ,  G01N21/3577 ,  G01N21/39 ,  G01N21/532 ,  G01N21/85 ,  G01N2021/399 ,  G01N2201/0612 ,  G01N2201/10

Abstract: A fluid analyzer includes an optical source and an optical detector defining an optical beam path through an interrogation region of a fluid flow cell. Motion control devices determine position of the interrogation region. Flow-control devices conduct analyte and reference fluids and manipulate fluid flow in response to control signals to position a fluid boundary across the interrogation region. A controller (1) generates a time-varying motion modulation signal to move the interrogation region across the fluid boundary, (2) samples an output signal from the optical detector at one time in which the interrogation region contains more analyte fluid than reference fluid and at a time at which the interrogation region contains more reference fluid than analyte fluid, thereby generating corresponding output signal samples, and (3) determines from the output signal samples a measurement value indicative of an optically measured characteristic of the analyte fluid.

Abstract translation: 流体分析器包括光源和光学检测器，其限定穿过流体流动池的询问区域的光束路径。 运动控制装置确定询问区域的位置。 流量控制装置进行分析物和参考流体，并响应于控制信号操纵流体流动，以便在询问区域上定位流体边界。 控制器（1）产生时变运动调制信号，以移动询问区域跨过流体边界，（2）在询问区域中包含比参考流体多的分析物流体的一次的时间对来自光学检测器的输出信号进行采样;以及 在询问区域包含比分析物流体更多的参考流体的时间，从而产生相应的输出信号样本，以及（3）从输出信号样本确定指示分析物流体的光学测量特性的测量值。