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公开(公告)号：US10646118B2
公开(公告)日：2020-05-12
申请号：US14586312
申请日：2014-12-30
Applicant: Regents of the University of Minnesota
Inventor： Timothy M. Kowalewski , Darrin D. Beekman , Jack B. Stubbs , Paul Anthony Iaizzo , Gregory K. Peterson
Abstract: Apparatus and methods for determining a type of a material in a region within a vascular system of a patient and/or a distance to the material are provided. At least one source fiber is provided that supplies light from a light source to a region within a vascular system of a patient. At least one return fiber is provided to receive light reflected from the region within the vascular system. At least one controller is provided to determine at least one property of the region within the vascular system from the reflected light, and to determine a type of a material in the region within the vascular system and/or an indication of a distance to the material. Techniques such as laser ablation may then be performed based on the determined material type and/or distance to remove unwanted buildup, deposits, etc., while avoiding harmful results such as tearing of tissue.
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2.发明申请LASER CATHETER WITH USE OF REFLECTED LIGHT AND FORCE INDICATION TO DETERMINE MATERIAL TYPE IN VASCULAR SYSTEM 审中-公开使用反射光和强度指示用于确定血管系统中材料类型的激光导管公开(公告)号：US20160184020A1
公开(公告)日：2016-06-30
申请号：US14586543
申请日：2014-12-30
Applicant: Regents of the University of Minnesota
Inventor： Timothy M. Kowalewski , Darrin D. Beekman , Sachin Bijadi
CPC classification number: A61B18/24 , A61B18/245 , A61B2018/00345 , A61B2018/00577 , A61B2018/00785 , A61B2090/065
Abstract: Apparatus and methods for determining a type of a material in a region within a vascular system of a patient are provided. The determination is made after light has been reflected from the region after being supplied to the region from a light source by at least one optical fiber. The determination is made based on an analysis of the light reflected from the region and of a received at least one indication of a force applied to the material in the region by one or more of the at least one optical fiber. The indication of the force applied by the one or more of the at least one optical fiber is provided by at least one force sensor coupled to the at least one optical fiber.
Abstract translation: 提供了用于确定患者的血管系统内的区域中的材料的类型的装置和方法。 在通过至少一根光纤从光源供给到该区域之后，从区域反射光后进行判定。 基于从该区域反射的光的分析以及所接收的至少一个光纤中的一个或多个施加到该区域中的材料的力的指示进行确定。 所述至少一个光纤中的一个或多个所施加的力的指示由耦合到所述至少一个光纤的至少一个力传感器提供。
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3.发明授权公开(公告)号：US10646275B2
公开(公告)日：2020-05-12
申请号：US14586529
申请日：2014-12-30
Applicant: Regents of the University of Minnesota
Inventor： Timothy M. Kowalewski , Darrin D. Beekman , Jack B. Stubbs , Gregory K. Peterson , Sachin Bijadi , Arthur G. Erdman
Abstract: Apparatus and methods for ablating material in a region within a vascular system of a patient are provided. A determination of at least one of a type of material in the region and an indication of a distance to the material in the region is made based on at least one property of the region determined from light reflected from the region. Light from a light source is transmitted in at least one of a plurality of optical fibers based on the determination, and at least some of the transmitted light is received at a first emitter disposed along a length of a laser catheter proximate a distal end thereof. The first emitter radially transmits the at least some of the light from the length of the laser catheter so that the light impinges upon and ablates the material through an opening in the length of the laser catheter.
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4.发明申请LASER CATHETER WITH USE OF REFLECTED LIGHT TO DETERMINE MATERIAL TYPE IN VASCULAR SYSTEM 审中-公开使用反射光的激光导管测定血管系统中的材料类型公开(公告)号：US20160183804A1
公开(公告)日：2016-06-30
申请号：US14586312
申请日：2014-12-30
Applicant: Regents of the University of Minnesota
Inventor： Timothy M. Kowalewski , Darrin D. Beekman , Jack B. Stubbs , Paul Anthony Iaizzo , Gregory K. Peterson
CPC classification number: A61B5/0084 , A61B5/02007 , A61B5/1076 , A61B5/4887 , A61B5/7282 , A61B18/245 , A61B2018/00345 , A61B2018/00577 , A61B2018/00785
Abstract: Apparatus and methods for determining a type of a material in a region within a vascular system of a patient and/or a distance to the material are provided. At least one source fiber is provided that supplies light from a light source to a region within a vascular system of a patient. At least one return fiber is provided to receive light reflected from the region within the vascular system. At least one controller is provided to determine at least one property of the region within the vascular system from the reflected light, and to determine a type of a material in the region within the vascular system and/or an indication of a distance to the material. Techniques such as laser ablation may then be performed based on the determined material type and/or distance to remove unwanted buildup, deposits, etc., while avoiding harmful results such as tearing of tissue.
Abstract translation: 提供了用于确定患者的血管系统内的区域中的材料的类型和/或与材料的距离的装置和方法。 提供至少一种源光纤，其将来自光源的光提供到患者的血管系统内的区域。 提供至少一个返回纤维以接收从血管系统内的区域反射的光。 提供至少一个控制器以从反射光确定血管系统内的区域的至少一个性质，并且确定血管系统内的区域中的材料的类型和/或与材料的距离的指示 。 然后可以基于确定的材料类型和/或距离来执行诸如激光烧蚀之类的技术，以消除不希望有的堆积物，沉积物等，同时避免诸如撕裂组织的有害结果。
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Patent Agency Ranking
公开(公告)号：US20230145742A1
公开(公告)日：2023-05-11
申请号：US17985488
申请日：2022-11-11
Applicant: Regents of the University of Minnesota
Inventor： Christopher J. Ellison , Timothy M. Kowalewski , Lorraine F. Francis , Matthew M. Hausladen , Boran Zhao , Matthew Kubala
CPC classification number: B25J18/02 , B29C48/09 , B29C48/94 , B29C48/91 , B29C2948/92066
Abstract: Some aspects of the present disclosure relate to systems and methods for polymer-based extrusion. Some non-limiting embodiments provide for extrusion of a liquid photopolymerizable monomer in a channel/die with the aid of a lubricating component, such as poly(dimethylsiloxane)-graft-poly(ethylene oxide) grafted copolymer (PDMS-PEO), and driven by fluid pressure (e.g., a fluid pump). Other aspects of the present disclosure relate to growing soft robots. Some non-limiting embodiments provide a novel class of robots which grow in an environment by growing at their tip (or robot head) by using the self-lubricated photopolymerization extrusion techniques of the present disclosure. Emulating biological tip growth, this process is facilitated by converting an internal monomer fluid into the solid body of the growing robot through polymerization.
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公开(公告)号：US10073522B2
公开(公告)日：2018-09-11
申请号：US14569380
申请日：2014-12-12
Applicant: Regents of the University of Minnesota
Inventor： Timothy M. Kowalewski , Sachin Bijadi , Darrin D. Beekman
CPC classification number: G06F3/014 , A61B42/10 , A61B2034/741 , G01L5/162 , G01L5/228
Abstract: An article of handwear for grasping a medical device in a medical environment includes a base adapted to be worn by a hand of a wearer. A sensor assembly is carried by the base. The sensor assembly is adapted to sense a force applied by the hand of the wearer, via the article of handwear, to the medical device. The sensor assembly is adapted to provide information regarding at least one shear component of the forces sensed by the sensor assembly.
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公开(公告)号：US10646274B2
公开(公告)日：2020-05-12
申请号：US14586543
申请日：2014-12-30
Applicant: Regents of the University of Minnesota
Inventor： Timothy M. Kowalewski , Darrin D. Beekman , Sachin Bijadi
Abstract: Apparatus and methods for determining a type of a material in a region within a vascular system of a patient are provided. The determination is made after light has been reflected from the region after being supplied to the region from a light source by at least one optical fiber. The determination is made based on an analysis of the light reflected from the region and of a received at least one indication of a force applied to the material in the region by one or more of the at least one optical fiber. The indication of the force applied by the one or more of the at least one optical fiber is provided by at least one force sensor coupled to the at least one optical fiber.
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8.发明申请LASER CATHETER WITH USE OF DETERMINED MATERIAL TYPE IN VASCULAR SYSTEM IN ABLATION OF MATERIAL 审中-公开在材料吸收中使用确定的材料类型在血管系统中的激光导管公开(公告)号：US20160184021A1
公开(公告)日：2016-06-30
申请号：US14586529
申请日：2014-12-30
Applicant: Regents of the University of Minnesota
Inventor： Timothy M. Kowalewski , Darrin D. Beekman , Jack B. Stubbs , Gregory K. Peterson , Sachin Bijadi , Arthur G. Erdman
IPC: A61B18/24
CPC classification number: A61B18/245 , A61B2018/00345 , A61B2018/00577 , A61B2018/00642 , A61B2018/00666 , A61B2018/00702 , A61B2018/00785 , A61B2018/00875 , A61B2018/00898 , A61B2018/00904 , A61B2018/2211
Abstract: Apparatus and methods for ablating material in a region within a vascular system of a patient are provided. A determination of at least one of a type of material in the region and an indication of a distance to the material in the region is made based on at least one property of the region determined from light reflected from the region. Light from a light source is transmitted in at least one of a plurality of optical fibers based on the determination, and at least some of the transmitted light is received at a first emitter disposed along a length of a laser catheter proximate a distal end thereof. The first emitter radially transmits the at least some of the light from the length of the laser catheter so that the light impinges upon and ablates the material through an opening in the length of the laser catheter.
Abstract translation: 提供了用于在患者的血管系统内的区域中烧蚀材料的装置和方法。 基于从该区域反射的光确定的区域的至少一个属性，确定该区域中的一种材料中的至少一种以及与该区域中材料的距离的指示。 基于该确定，来自光源的光在多个光纤中的至少一个传输，并且至少一些透射光在沿着其远端处的激光导管的长度设置的第一发射器处被接收。 第一发射器径向地透射来自激光导管的长度的至少一些光，使得光通过激光导管的长度上的开口撞击并消融材料。
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公开(公告)号：US20160169754A1
公开(公告)日：2016-06-16
申请号：US14569380
申请日：2014-12-12
Applicant: Regents of the University of Minnesota
Inventor： Timothy M. Kowalewski , Sachin Bijadi , Darrin D. Beekman
CPC classification number: G06F3/014 , A61B42/10 , A61B2034/741 , G01L5/162 , G01L5/228
Abstract: An article of handwear for grasping a medical device in a medical environment includes a base adapted to be worn by a hand of a wearer. A sensor assembly is carried by the base. The sensor assembly is adapted to sense a force applied by the hand of the wearer, via the article of handwear, to the medical device. The sensor assembly is adapted to provide information regarding at least one shear component of the forces sensed by the sensor assembly.
Abstract translation: 用于在医疗环境中抓住医疗装置的手套用品包括适于佩戴者的手佩戴的基部。 传感器组件由基座承载。 传感器组件适于感测穿过穿戴者的手通过手提物品施加到医疗装置上的力。 传感器组件适于提供关于由传感器组件感测的力的至少一个剪切分量的信息。
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