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公开(公告)号:US10060907B2
公开(公告)日:2018-08-28
申请号:US15438859
申请日:2015-08-21
Applicant: Roche Diagnostics Operations, Inc.
Inventor: Peter Gebauer , Dieter Heindl , Carina Horn , Maksim Fomin
IPC: G01N33/52 , G01N33/50 , C07D241/42 , C07D403/06
CPC classification number: G01N33/52 , C07D241/40 , C07D241/42 , C07D401/06 , C07D403/06 , G01N33/5005
Abstract: The present invention relates to a chemical compound or a salt or solvate thereof being a phenazine-, phenanthridine-, phenanthroline-, quinoline-, quinoxaline-, acridine-isoquinoline-, pyrazine- or pyridine-derivative comprising a conjugated π-system and a π-acceptor group, and to uses thereof. The present invention further relates to a chemistry matrix and to a test element comprising the chemical compound of the present invention. The present invention also relates to a method of determining the amount of an analyte in a test sample, comprising contacting said test sample with a chemical compound, with a chemistry matrix, or with a test element of the invention and estimating the amount of redox equivalents liberated or consumed by the chemical compound, by the chemical compound comprised in said chemistry matrix, or by the chemical compound comprised in said test element, in the presence of said test sample, thereby determining the amount of an analyte in said test sample. Moreover, the present invention relates to a system comprising a test element according to the present invention and a device comprising a sensor for measuring the amount of redox equivalents liberated or consumed.
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公开(公告)号:US20170191990A1
公开(公告)日:2017-07-06
申请号:US15438859
申请日:2015-08-21
Applicant: Roche Diagnostics Operations, Inc.
Inventor: Peter Gebauer , Dieter Heindi , Carina Horn , Maksim Fomin
IPC: G01N33/52 , C07D241/42 , C07D403/06 , G01N33/50
CPC classification number: G01N33/52 , C07D241/40 , C07D241/42 , C07D401/06 , C07D403/06 , G01N33/5005
Abstract: The present invention relates to a chemical compound or a salt or solvate thereof being a phenazine-, phenanthridine-, phenanthroline-, quinoline-, quinoxaline-, acridine- isoquinoline-, pyrazine- or pyridine-derivative comprising a conjugated π-system and a π-acceptor group, and to uses thereof. The present invention further relates to a chemistry matrix and to a test element comprising the chemical compound of the present invention. The present invention also relates to a method of determining the amount of an analyte in a test sample, comprising contacting said test sample with a chemical compound, with a chemistry matrix, or with a test element of the invention and estimating the amount of redox equivalents liberated or consumed by the chemical compound, by the chemical compound comprised in said chemistry matrix, or by the chemical compound comprised in said test element, in the presence of said test sample, thereby determining the amount of an analyte in said test sample. Moreover, the present invention relates to a system comprising a test element according to the present invention and a device comprising a sensor for measuring the amount of redox equivalents liberated or consumed.
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公开(公告)号:US20240103006A1
公开(公告)日:2024-03-28
申请号:US18468249
申请日:2023-09-15
Applicant: Roche Diagnostics Operations, Inc.
Inventor: Maksim Fomin , Hannes Kuchelmeister
IPC: G01N33/68 , C07C259/06
CPC classification number: G01N33/6845 , C07C259/06 , G01N33/6842
Abstract: The present invention relates to chemical probes for the improved detection of cysteine in a test sample, preferably an aqueous test sample, as well as respective uses and kits.
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公开(公告)号:US20230333095A1
公开(公告)日:2023-10-19
申请号:US18339799
申请日:2023-06-22
Applicant: Roche Diagnostics Operations, Inc.
Inventor: Maksim Fomin , Dieter Heindl , Lars Hillringhaus , Hannes Kuchelmeister , Mohamed Yosry Hassan Mohamed , Tobias Oelschlaegel , Sona Simonyiova
IPC: G01N33/533 , G01N33/68 , C07F15/02
CPC classification number: G01N33/533 , G01N33/6887 , C07F15/025 , G01N2800/325
Abstract: The present invention relates to a method for determining at least one analyte of interest. The present invention further relates to a kit, a complex, a method to synthesize a complex and the use thereof for detecting the analyte of interest in the sample.
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