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公开(公告)号：US20150147750A1
公开(公告)日：2015-05-28
申请号：US14609552
申请日：2015-01-30
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Frank Bergmann , Robert Cysewski , Luisa de Cola , Sebastian Dziadek , Jesus Miguel Fernandez Hernandez , Hans-Peter Josel , Christoph Seidel
CPC classification number: C07F15/0033 , C09K11/06 , C09K11/07 , C09K2211/1003 , C09K2211/1007 , C09K2211/1011 , C09K2211/1029 , C09K2211/1059 , C09K2211/1074 , C09K2211/14 , C09K2211/185 , G01N33/582
Abstract: The present invention relates to novel iridium-based Ir(III) luminescent complexes, conjugates comprising these complexes as a label and their application, e.g. in the electrochemiluminescence based detection of an analyte.
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公开(公告)号：US09416150B2
公开(公告)日：2016-08-16
申请号：US14609649
申请日：2015-01-30
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Frank Bergmann , Robert Cysewski , Luisa de Cola , Sebastian Dziadek , Jesus Miguel Fernandez Hernandez , Hans-Peter Josel , Christoph Seidel
CPC classification number: C07F15/0033 , C09K11/06 , C09K11/07 , C09K2211/1007 , C09K2211/1029 , C09K2211/14 , C09K2211/1408 , C09K2211/1416 , C09K2211/1425 , C09K2211/1441 , C09K2211/1466 , C09K2211/185 , G01N33/582
Abstract: The present invention relates to novel iridium-based Ir(III) luminescent complexes, conjugates comprising these complexes as a label and their application, e.g. in the electrochemiluminescence based detection of an analyte.
Abstract translation: 本发明涉及新型的基于铱的Ir（III）发光复合物，包含这些络合物作为标记的缀合物及其应用，例如， 在基于电化学发光的分析物检测中。
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公开(公告)号：US09403859B2
公开(公告)日：2016-08-02
申请号：US14610372
申请日：2015-01-30
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Frank Bergmann , Robert Cysewski , Luisa de Cola , Sebastian Dziadek , Jesus Miguel Fernandez Hernandez , Hans-Peter Josel , Christoph Seidel
CPC classification number: C07F15/0033 , C09K11/06 , C09K2211/1007 , C09K2211/1011 , C09K2211/1029 , C09K2211/14 , C09K2211/1408 , C09K2211/1416 , C09K2211/1425 , C09K2211/1441 , C09K2211/1466 , C09K2211/185 , G01N33/582
Abstract: The present invention relates to novel iridium-based Ir(III) luminescent complexes, conjugates comprising these complexes as a label and their application, e.g. in the electrochemiluminescence based detection of an analyte.
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公开(公告)号：US09399654B2
公开(公告)日：2016-07-26
申请号：US14609552
申请日：2015-01-30
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Frank Bergmann , Robert Cysewski , Luisa de Cola , Sebastian Dziadek , Jesus Miguel Fernandez Hernandez , Hans-Peter Josel , Christoph Seidel
CPC classification number: C07F15/0033 , C09K11/06 , C09K11/07 , C09K2211/1003 , C09K2211/1007 , C09K2211/1011 , C09K2211/1029 , C09K2211/1059 , C09K2211/1074 , C09K2211/14 , C09K2211/185 , G01N33/582
Abstract: The present invention relates to novel iridium-based Ir(III) luminescent complexes, conjugates comprising these complexes as a label and their application, e.g. in the electrochemiluminescence based detection of an analyte.
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公开(公告)号：US20150147751A1
公开(公告)日：2015-05-28
申请号：US14609649
申请日：2015-01-30
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Frank Bergmann , Robert Cysewski , Luisa de Cola , Sebastian Dziadek , Jesus Miguel Fernandez Hernandez , Hans-Peter Josel , Christoph Seidel
CPC classification number: C07F15/0033 , C09K11/06 , C09K11/07 , C09K2211/1007 , C09K2211/1029 , C09K2211/14 , C09K2211/1408 , C09K2211/1416 , C09K2211/1425 , C09K2211/1441 , C09K2211/1466 , C09K2211/185 , G01N33/582
Abstract: The present invention relates to novel iridium-based Ir(III) luminescent complexes, conjugates comprising these complexes as a label and their application, e.g. in the electrochemiluminescence based detection of an analyte.
Abstract translation: 本发明涉及新型的基于铱的Ir（III）发光复合物，包含这些络合物作为标记的缀合物及其应用，例如， 在基于电化学发光的分析物检测中。
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Patent Agency Ranking
公开(公告)号：US20150140682A1
公开(公告)日：2015-05-21
申请号：US14610372
申请日：2015-01-30
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Frank Bergmann , Robert Cysewski , Luisa de Cola , Sebastian Dziadek , Jesus Miguel Fernandez Hernandez , Hans-Peter Josel , Christoph Seidel
CPC classification number: C07F15/0033 , C09K11/06 , C09K2211/1007 , C09K2211/1011 , C09K2211/1029 , C09K2211/14 , C09K2211/1408 , C09K2211/1416 , C09K2211/1425 , C09K2211/1441 , C09K2211/1466 , C09K2211/185 , G01N33/582
Abstract: The present invention relates to novel iridium-based Ir(III) luminescent complexes, conjugates comprising these complexes as a label and their application, e.g. in the electrochemiluminescence based detection of an analyte.
Abstract translation: 本发明涉及新型的基于铱的Ir（III）发光复合物，包含这些络合物作为标记的缀合物及其应用，例如， 在基于电化学发光的分析物检测中。
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公开(公告)号：US20220018851A1
公开(公告)日：2022-01-20
申请号：US17265154
申请日：2019-08-08
Applicant: Hoffmann-La Roche Inc. , Roche Diagnostics Operations, Inc. , Ventana Medical Systems, Inc. , Prothena Biosciences Limited
Inventor： Christian Czech , Sebastian Dziadek , Lidija Pestic-Dragovich , Lei Tang , Thomas Kremer , Wagner Marcelo Zago , Tsu-Shuen Tsao , Adriana Racolta , Marta Canamero , Ronald Torres , Mirko Ritter
IPC: G01N33/68
Abstract: Methods and compositions for accurate identification of Parkinson's disease are disclosed. More particularly, the disclosure is directed to the determination of Parkinson's disease in ante-mortem tissue samples.
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公开(公告)号：US20170096487A1
公开(公告)日：2017-04-06
申请号：US15083686
申请日：2016-03-29
Inventor： Monika Soukupova , Michael Schraeml , Birgit Bossenmaier , Patrick C. Roche , Michael Gerg , Sebastian Dziadek
IPC: C07K16/28 , G01N33/574 , C07K16/30 , G01N33/74 , G01N1/30
CPC classification number: C07K16/2863 , C07K16/3023 , C07K16/3046 , C07K16/32 , C07K2317/33 , C07K2317/56 , C07K2317/565 , C07K2317/92 , C07K2317/94 , G01N1/30 , G01N33/57492 , G01N33/74 , G01N2001/302 , G01N2333/71
Abstract: The present invention relates to isolated antibodies, or an antigen portions thereof, which bind to human HER3. The novel antibodies are of great utility since they allow for the sensitive and specific detection of human HER3. Detection of human HER3 is, e.g., possible in a tissue sample, even when such tissue sample is a formalin-fixed paraffin embedded tissue (FFPET) sample.
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公开(公告)号：US09499573B2
公开(公告)日：2016-11-22
申请号：US14610244
申请日：2015-01-30
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Frank Bergmann , Robert Cysewski , Luisa de Cola , Sebastian Dziadek , Jesus Miguel Fernandez Hernandez , Hans-Peter Josel , Elena Longhi , Christoph Seidel
CPC classification number: C07F15/0033 , C09K11/06 , C09K2211/1007 , C09K2211/1029 , C09K2211/1059 , C09K2211/14 , C09K2211/1416 , C09K2211/1425 , C09K2211/1441 , C09K2211/1466 , C09K2211/1475 , C09K2211/1491 , C09K2211/185 , G01N33/582 , G01N2458/30
Abstract: The present invention relates to novel iridium-based Ir(III) luminescent complexes, conjugates comprising these complexes as a label and their application, e.g. in the electrochemiluminescence based detection of an analyte.
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公开(公告)号：US20150147752A1
公开(公告)日：2015-05-28
申请号：US14610244
申请日：2015-01-30
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Frank Bergmann , Robert Cysewski , Luisa de Cola , Sebastian Dziadek , Jesus Miguel Fernandez Hernandez , Hans-Peter Josel , Elena Longhi , Christoph Seidel
CPC classification number: C07F15/0033 , C09K11/06 , C09K2211/1007 , C09K2211/1029 , C09K2211/1059 , C09K2211/14 , C09K2211/1416 , C09K2211/1425 , C09K2211/1441 , C09K2211/1466 , C09K2211/1475 , C09K2211/1491 , C09K2211/185 , G01N33/582 , G01N2458/30
Abstract: The present invention relates to novel iridium-based Ir(III) luminescent complexes, conjugates comprising these complexes as a label and their application, e.g. in the electrochemiluminescence based detection of an analyte.
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