公开(公告)号：US20210023626A1

公开(公告)日：2021-01-28

申请号：US16961174

申请日：2019-01-10

Applicant: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION ,  BIONANO HEALTH GUARD RESEARCH CENTER

Inventor： Jwa-Min NAM ,  Minho KIM ,  Sung Min KO

IPC: B22F9/24 ,  B22F1/02

Abstract: The present invention relates to a method for preparing a core-gap-shell nanoparticle having an average height of 0.1 nm to 10 nm, in which a Raman-active material is disposed between a core and a shell, and more specifically, to a method for preparing a core-gap-shell nanoparticle, which comprises introducing a shell made of an alloy of a second metal and a third metal, on the core particles of the first metal, the surface of which is modified with a Raman-active material; selectively removing the second metal by treating with a second metal etchant, followed by dealloying; the core-gap-shell nanoparticle prepared by the above method comprising a Raman-active material disposed in the gap, and uses of the core-gap-shell nanoparticle for biosensing and/or bioimaging.

公开(公告)号：US20200011864A1

公开(公告)日：2020-01-09

申请号：US16486674

申请日：2018-02-14

Applicant: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION ,  KOREA FOOD & DRUG ADMINISTRATION

Inventor： Jwa-Min NAM ,  Gwangpyo KO ,  Jae-Ho KIM ,  Jeong-Eun PARK ,  Mouhong LIN ,  In Sun JOO ,  Jeong Su LEE

IPC: G01N33/553 ,  G01N33/532 ,  G01N33/543

Abstract: The present invention relates to a method for detecting a target analyte using a gold nanoparticle, comprising growing a copper crystal specifically on a gold nanoparticle by treating the gold nanoparticle with a solution comprising a copper ion, a polymer having a primary or secondary amine group, and a reducing agent, a composition for amplifying a signal used in the detection method above, and a kit for detecting a target analyte comprising the composition for amplifying a signal above.

公开(公告)号：US20250155279A1

公开(公告)日：2025-05-15

申请号：US18838251

申请日：2023-08-01

Applicant: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION

Inventor： Jwa-Min NAM ,  Yoonhee KIM

IPC: G01J1/02 ,  B82Y15/00 ,  B82Y20/00

Abstract: Provided according to an embodiment of the present subject matter is a nanocatenane structure including at least two chained ring structures, each structure consisting of a core and a shell covering the core, wherein the chained ring structures are chemically coupled in a joining area.

公开(公告)号：US20250041898A1

公开(公告)日：2025-02-06

申请号：US18720325

申请日：2022-12-16

Applicant: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION ,  BIONANO HEALTH GUARD RESEARCH CENTER

Inventor： Jwa-Min NAM ,  Yeon Hee LEE ,  Seungsang CHA ,  Yuna KWAK

IPC: B05D7/14

Abstract: The present invention relates to a method for preparing a two-dimensional or three-dimensional nanocube self-assembled structure and a two-dimensional or three-dimensional nanocube self-assembled structure prepared by the preparation method and, more specifically, to a two-dimensional or three-dimensional nanocube self-assembled structure which has uniform and regular nanogaps and high crystallinity and thus has high optical utilization.

公开(公告)号：US20230382939A1

公开(公告)日：2023-11-30

申请号：US18246944

申请日：2021-09-06

Applicant: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION ,  BIONANO HEALTH GUARD RESEARCH CENTER

Inventor： Jwa-Min NAM ,  Jae-Myoung KIM ,  Jiyeon KIM

IPC: C07H5/10 ,  C07C211/62 ,  C01F17/271 ,  C07D307/33

CPC classification number: C07H5/10 ,  C07C211/62 ,  B82Y40/00 ,  C07D307/33 ,  C01F17/271

Abstract: Provided is a nanoparticle including: a core structure; and a shell structure covering the core structure and separated from the core structure by a nanogap, wherein a macrocyclic host molecule exhibiting hydrophobicity inside and hydrophilicity outside and a Raman-active material inserted into the macrocyclic host molecule are provided on a surface of the core structure, and the macrocyclic host molecule and the Raman-active material fill the nanogap.

公开(公告)号：US20210365798A1

公开(公告)日：2021-11-25

申请号：US17328765

申请日：2021-05-24

Applicant: Seoul National University R&DB Foundation

Inventor： Jwa-Min NAM ,  Sungi KIM ,  Namjun KIM

IPC: G06N3/12 ,  G11C13/02

Abstract: A nano computing device includes: a nanoparticle memory including a first molecule bound so as to store a molecular input; a nanoparticle reporter including a second molecule bound so as to generate an output; and a nanoparticle floater including at least two third molecules and fourth molecules so as to be bound to one of the nanoparticle memory and the nanoparticle reporter based on the molecular input and an instruction molecule.

公开(公告)号：US20210161952A1

公开(公告)日：2021-06-03

申请号：US15733420

申请日：2019-01-25

Applicant: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION ,  BIONANO HEALTH GUARD RESEARCH CENTER

Inventor： Jwa-Min NAM ,  Jeong-Eun PARK ,  Yeon Hee LEE

IPC: A61K33/242 ,  C09K11/58 ,  A61K9/14 ,  B22F9/24 ,  B22F1/00

Abstract: The present invention relates to a method for preparing a metal nanocube with a controlled corner sharpness index, comprising a step of reacting with a first surfactant and a predetermined surface-protecting agent; a method for preparing a metal nanocube aggregate having a purity of 95% or more, comprising a step of centrifuging in the presence of a second surfactant; a probe composition comprising the metal nanocube or metal nanocube aggregate prepared by the method; and a gold (Au) nanocube having an average edge length of 20 nm or less.