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    Preprocessing device and analysis system provided with same
    1.
    发明授权
    Preprocessing device and analysis system provided with same 有权

    公开(公告)号：US11162924B2

    公开(公告)日：2021-11-02

    申请号：US16691927

    申请日：2019-11-22

    Applicant: SHIMADZU CORPORATION

    Inventor： Nobuhiro Hanafusa ,  Kazuhiro Suzuki

    IPC: G01N30/24 ,  G01N35/02 ,  G01N30/88 ,  G01N35/00 ,  G01N1/10 ,  G01N35/04 ,  G01N27/62 ,  G01N30/36 ,  G01N30/06 ,  G01N35/10

    Abstract: The present invention provides a processing device with a high degree of flexibility in setting of preprocessing and which is capable of increasing the preprocessing efficiency, and an analysis system provided with the same. Setting receiving means (84d) receives, for each sample, setting of a plurality of types of preprocessing and a parameter for each preprocessing. A preprocessing execution section (84e) controls a plurality of preprocessing sections and a transport arm (24) so that a plurality of types of preprocessing set for each of different samples is performed simultaneously in parallel. The preprocessing execution section (84e) performs control in such a way that preprocessing is not to be performed on different samples at the same preprocessing section at the same.

    Pretreatment device, and analysis system provided with same
    2.
    发明授权
    Pretreatment device, and analysis system provided with same 有权

    公开(公告)号：US11092575B2

    公开(公告)日：2021-08-17

    申请号：US15741789

    申请日：2015-07-09

    Applicant: SHIMADZU CORPORATION

    Inventor： Nobuhiro Hanafusa ,  Kazuhiro Suzuki

    IPC: G01N30/06 ,  B01L9/00 ,  G01N35/04 ,  G01N35/02 ,  G01N35/00 ,  G01N30/72 ,  G01N30/02

    Abstract: Provided are a pretreatment device capable of starting pretreatment in a simple operation, and an analysis system provided with the pretreatment device. A container holding unit 12 holds pretreatment containers into each of which a sample is injected, at a plurality of holding positions. A pretreatment unit sequentially performs pretreatment by using the pretreatment containers held at the holding positions of the container holding unit 12 in a specific order. A controller configured to receives a setting of the holding position of a pretreatment container to be used first among the plurality of holding positions in the case where a series of pretreatments using the plurality of pretreatment containers is started by the pretreatment unit.

    Sample extraction tool
    4.
    发明授权
    Sample extraction tool 有权

    公开(公告)号：US11333583B2

    公开(公告)日：2022-05-17

    申请号：US16407302

    申请日：2019-05-09

    Applicant: SHIMADZU CORPORATION

    Inventor： Nobuhiro Hanafusa

    IPC: G01N1/08 ,  G01N1/28

    Abstract: An extraction portion which is a piece of a micro sampling chip is safely cut, and the cut extraction portion can be accommodated in a predetermined container without impairing quantitativeness of a sample.
    A sample extraction tool comprises a through hole for cutting the extraction portion from the micro sampling chip by bending the micro sampling chip while inserting the extraction portion to the through hole, the sample extraction tool is configured to be attached to an upper portion of a container for accommodating the extraction portion in such a state that the through hole is disposed on an open upper surface of the container.

    Preprocessing apparatus
    6.
    发明授权
    Preprocessing apparatus 有权

    公开(公告)号：US11604203B2

    公开(公告)日：2023-03-14

    申请号：US16718330

    申请日：2019-12-18

    Applicant: SHIMADZU CORPORATION

    Inventor： Nobuhiro Hanafusa

    IPC: G01N35/02 ,  G01N35/10 ,  G01N35/04

    Abstract: A pretreatment device for performing pretreatment using a liquid sucked by a probe from an inside of a septum-attached container includes: a container holding unit which has a space for accommodating the septum-attached container and is provided with a hole into which the probe is inserted with respect to a septum of the septum-attached container to be stored; an installation unit in which the container holding unit is detachably installed; and a fixing unit which fixes the container holding unit to the installation unit in a state where the container holding unit is detachably installed in the installation unit, to solve the above-described problem.

    Controlling method of preprocessing apparatus
    7.
    发明授权
    Controlling method of preprocessing apparatus 有权

    公开(公告)号：US11441975B2

    公开(公告)日：2022-09-13

    申请号：US15322527

    申请日：2014-07-02

    Applicant: SHIMADZU CORPORATION

    Inventor： Nobuhiro Hanafusa ,  Masamitsu Shikata

    IPC: G01N1/10 ,  G01N30/06 ,  G01N1/34 ,  G01N35/02 ,  G01N1/40 ,  G01N35/00 ,  B01L3/00 ,  G01N1/14 ,  G01N35/04

    Abstract: A preprocessing apparatus uses preprocessing kits prepared for samples, respectively, sets the preprocessing kits in plural processing ports provided so as to correspond to preprocessing items, and executes a predetermined preprocessing item. A controller which controls operations of a carrying mechanism holding and carrying the preprocessing kits, and processing parts executing the preprocessing items in the respective processing ports, includes a processing-state control part, a random access part, and a preprocessing part. The random access part is configured to check availability of a preprocessing port corresponding to a preprocessing item to be executed on a sample contained in a preprocessing kit, and set the preprocessing kit in a processing port if the processing port is available as a processing port corresponding to the preprocessing item. The preprocessing part executes a corresponding preprocessing item on a sample in a preprocessing kit when the preprocessing kit is set in the processing port.

    Preprocessing apparatus and analysis system comprising the preprocessing apparatus
    9.
    发明授权
    Preprocessing apparatus and analysis system comprising the preprocessing apparatus 有权

    公开(公告)号：US11385206B2

    公开(公告)日：2022-07-12

    申请号：US17009302

    申请日：2020-09-01

    Applicant: SHIMADZU CORPORATION

    Inventor： Nobuhiro Hanafusa

    IPC: G01N30/06 ,  G01N1/28 ,  G01N1/40 ,  G01N33/49 ,  G01N35/00 ,  G01N35/04 ,  B01L3/00 ,  G01N35/10 ,  G01N30/00 ,  G01N30/02

    Abstract: Disclosed herein is a preprocessing apparatus that makes it possible to highly efficiently analyze specimens held by solid media, such as dried blood spots to be used for newborn mass screening or the like. The preprocessing apparatus includes: a preprocessing container setting part in which a preprocessing container containing a solid sample including a specimen to be analyzed and a solid medium holding the specimen is to be set; a carrying mechanism that carries the preprocessing container set in the preprocessing container setting part; and a preprocessing part that has a port for setting the preprocessing container carried by the carrying mechanism and that is configured to perform preprocessing including extraction processing for extracting the specimen from the solid sample contained in the preprocessing container set in the port.

    Micro droplet operation device and reaction processing method using the same
    10.
    发明授权
    Micro droplet operation device and reaction processing method using the same 有权

    公开(公告)号：US10029253B2

    公开(公告)日：2018-07-24

    申请号：US14052299

    申请日：2013-10-11

    Applicant: SHIMADZU CORPORATION

    Inventor： Masakazu Akechi ,  Masaki Kanai ,  Takahiro Nishimoto ,  Nobuhiro Hanafusa

    IPC: B01L3/00 ,  C12M1/32 ,  G01N35/00 ,  G01N35/10

    Abstract: Micro droplets are accurately placed in a reaction well. The reaction well (5) is formed in one surface of a well base (3). A channel base (11) is placed on the well base (3). The channel base (11) has, in its surface joined to the well base (3), a liquid introduction channel (12a) and a reaction well air vent channel (18a). The channel base (11) also has a recess (27) formed opposite to the reaction well (5) and recessed upward from the upper surface of the liquid introduction channel (12a). When viewed from above, a shoulder part (26) of the recess (27) is placed near the connection part between the reaction well (5) and the liquid introduction channel (12a) and is closer to the center of the reaction well (5) than a shoulder part (16) of the reaction well (5).

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