公开(公告)号：US20240368551A1

公开(公告)日：2024-11-07

申请号：US18653210

申请日：2024-05-02

Applicant: SINAI HEALTH SYSTEM

Inventor： Adele CHANGOOR ,  Sarah Linda ALOI ,  Marc Daniel GRYNPAS

IPC: C12N5/077

Abstract: The specification provides an improved media formulation to enhance the viability of chondrocytes in stored biological samples. The formulation includes Dulbecco's Modified Eagle Medium (DMEM), doxycycline, and hyaluronic acid, in concentrations sufficient to maintain the chondrocytes' viability significantly longer than DMEM alone. This formulation allows biological samples containing chondrocytes to retain high viability rates for extended periods to be suitable for transplant purposes, such as in osteochondral tissue transplantation.