公开(公告)号：US20250025607A1

公开(公告)日：2025-01-23

申请号：US18714809

申请日：2023-02-23

Applicant: SINO MEDICAL SCIENCES TECHNOLOGY, INC.

Inventor： Christophe BUREAU ,  Ran SONG ,  Xiaomei ZHANG ,  Zhongcheng PAN ,  Hongtao FAN

IPC: A61L29/16 ,  A61L29/06

Abstract: A drug eluting balloon loaded with a drug in bulk, without any extra coating to host the said drug, and the method of preparing a drug eluting balloon which directly loads the drug on the balloon without coating, by using supercritical carbon dioxide to dissolve the drug and impregnate the balloons. The carbon dioxide is then released by pressure reduction, leaving only the drug on the balloon. Under suitable processing conditions, this method can form the drug uniformly on the surface of the balloon while maintaining the exterior morphology of the balloon, with a minimal increase in balloon thickness, and achieve satisfactory drug loading.