公开(公告)号：US3701775A

公开(公告)日：1972-10-31

申请号：US3701775D

申请日：1970-11-25

Applicant: SMITH KLINE FRENCH LAB

Inventor： BERGES DAVID A ,  DUNN GEORGE L ,  HOOVER JOHN R E

IPC: A61K20060101 ,  C07C20060101 ,  C07D20060101 ,  C07D501/20 ,  C07D501/32 ,  C07D99/24

CPC classification number: C07D501/20 ,  Y02P20/55

Abstract: ESTERS OF MANDELAMIDOCEPHALOSPORANIC ACIDS HAVING ANTIBACTERIAL ACTIVITY ARE PREPARED BY CONDENSING THE MANDELAMIDOCEPHALOSPORIN WITH A CARBOXYLIC ACID. PREFERRED COMPOUNDS INCLUDE THOSE WHERE THE CARBOXYLIC ACID IS AN AMINO ACID.