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公开(公告)号：US20200078455A1
公开(公告)日：2020-03-12
申请号：US16607604
申请日：2018-04-24
Applicant: SRI INTERNATIONAL
Inventor： Nathalie Scholler , Paul Stein , Lidia Sambucetti
Abstract: Disclosed are compositions comprising a mesothelin protein and an adjuvant. Disclosed are compositions comprising a mesothelin protein, an adjuvant, and a second adjuvant. In some instances the adjuvant is cyclic dinucleotides (CDNs). Disclosed are compositions comprising a mesothelin protein, CDNs, and a squalene based oil-in-water emulsion. Disclosed are methods of treating cancer comprising administering to a subject a composition or vaccine, wherein the composition or vaccine comprises a mesothelin protein, an adjuvant, and a second adjuvant.
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