公开(公告)号：US09408392B2

公开(公告)日：2016-08-09

申请号：US14375801

申请日：2013-02-14

Applicant: SYNGENTA PARTICIPATIONS AG

Inventor： Anthony Cornelius O'Sullivan ,  Olivier Loiseleur ,  Daniel Stierli ,  Torsten Luksch ,  Thomas Pitterna

IPC: C07C233/64 ,  C07C233/65 ,  C07C311/49 ,  C07D213/81 ,  C07D231/14 ,  C07D233/64 ,  C07D237/24 ,  C07D239/28 ,  C07D241/24 ,  C07D307/68 ,  A01N37/18 ,  A01N43/40 ,  A01N51/00 ,  A01N43/08 ,  A01N43/10 ,  A01N43/12 ,  A01N43/36 ,  A01N43/42 ,  A01N43/50 ,  A01N43/54 ,  A01N43/56 ,  A01N43/80 ,  A01N43/58 ,  A01N43/60

CPC classification number: A01N51/00 ,  A01N37/18 ,  A01N43/08 ,  A01N43/10 ,  A01N43/12 ,  A01N43/36 ,  A01N43/40 ,  A01N43/42 ,  A01N43/50 ,  A01N43/54 ,  A01N43/56 ,  A01N43/58 ,  A01N43/60 ,  A01N43/80 ,  C07C233/64 ,  C07C233/65 ,  C07C311/49 ,  C07D213/81 ,  C07D231/14 ,  C07D233/64 ,  C07D237/24 ,  C07D239/28 ,  C07D241/24 ,  C07D307/68

Abstract: Compounds of the formula (I), in which the substituents are as defined in claim 1, are suitable for use as nematicides.

Abstract translation: 其中取代基如权利要求1中所定义的式（I）化合物适合用作杀线虫剂。

公开(公告)号：US20140287916A1

公开(公告)日：2014-09-25

申请号：US14354043

申请日：2012-10-31

Applicant: SYNGENTA PARTICIPATIONS AG

Inventor： Olivier Loiseleur ,  Thomas Pitterna ,  Anthony Cornelius O'Sullivan ,  Torsten Luksch

IPC: A01N43/78 ,  A01N43/60 ,  A01N43/58 ,  A01N43/54

CPC classification number: A01N43/78 ,  A01N43/54 ,  A01N43/58 ,  A01N43/60 ,  C07D237/08 ,  C07D237/12 ,  C07D239/26 ,  C07D241/16 ,  C07D241/18 ,  C07D277/22 ,  C07D277/32 ,  C07D403/12 ,  C07D417/12

Abstract: A compound of formula (I), wherein R1 to R4 are, for example, each hydrogen, R5 is, for example, an unsubstituted aromatic 6-membered heterocycle; R6 is, for example, hydrogen; R7 is, for example, hydrogen, cyano, hydroxyl, formyl, C1-C4-alkyl, C1-C4-alkoxy, C2-C4-alkenyl, or C2-C4-alkynyl; and A1 to A5 are, independently selected, from, for example, N, and C—H; and its use as a pesticidal agent.

Abstract translation: 式（I）化合物，其中R 1至R 4为例如各自的氢，R 5为例如未取代的芳香族6-元杂环; R6是例如氢; R 7为例如氢，氰基，羟基，甲酰基，C 1 -C 4 - 烷基，C 1 -C 4 - 烷氧基，C 2 -C 4 - 烯基或C 2 -C 4 - 炔基; 并且A1至A5独立地选自例如N和C-H; 并用作杀虫剂。

公开(公告)号：US20150223456A1

公开(公告)日：2015-08-13

申请号：US14690950

申请日：2015-04-20

Applicant: SYNGENTA PARTICIPATIONS AG ,  SYNGENTA LIMITED

Inventor： Thomas Pitterna ,  Olivier Loiseleur ,  Paul Anthony Worthington ,  Anthony Cornelius O'Sullivan ,  Torsten Luksch ,  Vladimir Bobosik

IPC: A01N43/40 ,  C07D213/71 ,  A01N43/58 ,  A01N43/60 ,  C07D213/40 ,  C07D401/12

CPC classification number: A01N43/40 ,  A01N43/54 ,  A01N43/58 ,  A01N43/60 ,  C07D213/40 ,  C07D213/61 ,  C07D213/71 ,  C07D213/81 ,  C07D213/82 ,  C07D213/85 ,  C07D213/89 ,  C07D401/12

Abstract: A compound of formula (I) wherein R1 to R4 are, for example, each hydrogen, R5 is pyridyl, which has two or more substituents selected, for example, from halogen, C1-C4-alkyl, C1-C4-haloalkyl, C1-C4-alkoxy, C1-C4-haloalkoxy, and cyano; R6 is, for example, hydrogen; R7 is, for example, hydrogen, cyano, hydroxyl, formyl, C1-C4-alkyl, C1-C4-alkoxy, C2-C4-alkenyl, or C2-C4-alkynyl; and A1 to A5 are, independently selected, from, for example, N, and C—H; and its use as a pesticidal agent.

Abstract translation: 其中R 1至R 4为例如每个氢的式（I）化合物，R 5为吡啶基，其具有两个或多个选自例如卤素，C 1 -C 4烷基，C 1 -C 4卤代烷基，C 1 -C 4卤代烷基 C 1-4 - 烷氧基，C 1 -C 4卤代烷氧基和氰基; R6是例如氢; R 7为例如氢，氰基，羟基，甲酰基，C 1 -C 4 - 烷基，C 1 -C 4 - 烷氧基，C 2 -C 4 - 烯基或C 2 -C 4 - 炔基; 并且A1至A5独立地选自例如N和C-H; 并用作杀虫剂。

公开(公告)号：US11053188B2

公开(公告)日：2021-07-06

申请号：US16764666

申请日：2018-11-14

Applicant: SYNGENTA PARTICIPATIONS AG

Inventor： Raphael Dumeunier ,  Tomas Smejkal ,  Brijnandan Premnath Mishra ,  Vijayagopal Raman Gopalsamuthiram ,  Edouard Godineau ,  Anthony Cornelius O'Sullivan

IPC: C07C231/06 ,  C07C45/44 ,  C07C49/593 ,  C07C49/467 ,  C07C49/647 ,  C07C49/697 ,  C07C49/39 ,  C07C231/02 ,  C07C211/40 ,  C07C45/54 ,  C07C209/26 ,  C07D213/803 ,  C07C47/457 ,  C07C233/58 ,  B01J21/02

Abstract: The present invention relates to a process for the preparation of enantiomerically and diastereomerically enriched cyclobutane amines and amides by reacting (a) cyclopropylcarbonitrile to a cyclopropylcarbaldehyde, (b) further reacting to a cyclobutanone, or (d′) further reacting to an enamide, (c) further reacting to enantiomerically and diastereomerically enriched cyclobutane amines, or (d) further reacting to an enamide and (e) to an enantiomerically and diastereomerically enriched cyclobutylamide to obtain (f) an enantiomerically and diastereomerically enriched cyclobutane amine, and (g) further reacting to an enantiomerically and diastereomerically enriched cyclobutane amide.

公开(公告)号：US20180271096A1

公开(公告)日：2018-09-27

申请号：US15762498

申请日：2016-09-22

Applicant: SYNGENTA PARTICIPATIONS AG

Inventor： Anthony Cornelius O'Sullivan ,  Myriem El Qacemi ,  Jérôme Yves Cassayre ,  Thomas Pitterna ,  André Stoller

IPC: A01N43/80 ,  C07D261/04 ,  C07D413/12

CPC classification number: A01N43/80 ,  C07D261/04 ,  C07D413/12 ,  C07D413/14

Abstract: Compounds of formula (I) wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts salts, stereoisomers, enantiomers, tautomers and N-oxides of those compounds, and their uses as insecticides.

公开(公告)号：US20150232424A1

公开(公告)日：2015-08-20

申请号：US14627402

申请日：2015-04-27

Applicant: SYNGENTA PARTICIPATIONS AG

Inventor： Thomas Pitterna ,  Olivier Loiseleur ,  Anthony Cornelius O'Sullivan ,  Torsten Luksch

IPC: C07D213/61 ,  A01N43/40 ,  C07D213/70 ,  C07D213/64 ,  C07D409/04 ,  C07D401/04 ,  A01N43/54 ,  C07D413/04 ,  A01N43/76 ,  A01N43/42 ,  A01N43/60 ,  C07D498/04 ,  A01N43/90 ,  C07D471/04 ,  C07D405/04

CPC classification number: C07D213/61 ,  A01N43/40 ,  A01N43/42 ,  A01N43/50 ,  A01N43/54 ,  A01N43/56 ,  A01N43/60 ,  A01N43/76 ,  A01N43/90 ,  A61K9/08 ,  A61K9/1075 ,  A61K9/143 ,  A61K9/145 ,  A61K9/1611 ,  A61K9/1652 ,  A61K31/443 ,  A61K31/4436 ,  A61K31/4439 ,  A61K31/444 ,  A61K31/4709 ,  A61K31/497 ,  A61K31/4985 ,  A61K31/506 ,  A61K45/06 ,  A61K47/02 ,  A61K47/10 ,  C07D213/64 ,  C07D213/70 ,  C07D401/04 ,  C07D405/04 ,  C07D405/14 ,  C07D409/04 ,  C07D413/04 ,  C07D471/04 ,  C07D498/04 ,  A61K2300/00

Abstract: A compound of formula (I) wherein R1 to R4 are, for example, each hydrogen, R5 is pyridyl, which has one or more substituents at least one of which is, for example, a 5 membered heterocycle; R7 is, for example, hydrogen, cyano, hydroxyl, formyl, C1-C4-alkyl, C1-C4-alkoxy, C2-C4-alkenyl, or C2-C4-alkynyl; and A1 to A5 are, independently selected, from, for example, N, and C—H; and its use as a pesticidal agent.

Abstract translation: 其中R 1至R 4为例如每个氢的式（I）化合物，R 5为吡啶基，其具有一个或多个取代基，其中至少一个为例如5元杂环; R 7为例如氢，氰基，羟基，甲酰基，C 1 -C 4 - 烷基，C 1 -C 4 - 烷氧基，C 2 -C 4 - 烯基或C 2 -C 4 - 炔基; 并且A1至A5独立地选自例如N和C-H; 并用作杀虫剂。

公开(公告)号：US20140296067A1

公开(公告)日：2014-10-02

申请号：US14354170

申请日：2012-10-31

Applicant: SYNGENTA PARTICIPATIONS AG ,  University of Exeter

Inventor： Thomas Pitterna ,  Olivier Loiseleur ,  Paul Anthony Worthington ,  Anthony Cornelius O'Sullivan ,  Torsten Luksch ,  Vladimir Bobosik

IPC: A01N43/60 ,  A01N43/58 ,  A01N43/54 ,  A01N43/40

CPC classification number: A01N43/40 ,  A01N43/54 ,  A01N43/58 ,  A01N43/60 ,  C07D213/40 ,  C07D213/61 ,  C07D213/71 ,  C07D213/81 ,  C07D213/82 ,  C07D213/85 ,  C07D213/89 ,  C07D401/12

Abstract: A compound of formula (I) wherein R1 to R4 are, for example, each hydrogen, R5 is pyridyl, which has two or more substituents selected, for example, from halogen, C1-C4-alkyl, C1-C4-haloalkyl, C1-C4-alkoxy, C1-C4-haloalkoxy, and cyano; R6 is, for example, hydrogen; R7 is, for example, hydrogen, cyano, hydroxyl, formyl, C1-C4-alkyl, C1-C4-alkoxy, C2-C4-alkenyl, or C2-C4-alkynyl; and A1 to A5 are, independently selected, from, for example, N, and C—H; and its use as a pesticidal agent.

Abstract translation: 其中R 1至R 4为例如每个氢的式（I）化合物，R 5为吡啶基，其具有两个或多个选自例如卤素，C 1 -C 4烷基，C 1 -C 4卤代烷基，C 1 -C 4卤代烷基 C 1-4 - 烷氧基，C 1 -C 4卤代烷氧基和氰基; R6是例如氢; R 7为例如氢，氰基，羟基，甲酰基，C 1 -C 4 - 烷基，C 1 -C 4 - 烷氧基，C 2 -C 4 - 烯基或C 2 -C 4 - 炔基; 并且A1至A5独立地选自例如N和C-H; 并用作杀虫剂。

公开(公告)号：US20140274692A1

公开(公告)日：2014-09-18

申请号：US14354185

申请日：2012-10-31

Applicant: Syngenta Participations AG

Inventor： Olivier Loiseleur ,  Thomas Pitterna ,  Anthony Cornelius O'Sullivan ,  Torsten Luksch ,  Anna Kickova

IPC: A01N37/18 ,  A01N43/58 ,  A01N43/54 ,  A01N43/60 ,  A01N43/40 ,  A01N37/34

CPC classification number: A01N37/18 ,  A01N37/34 ,  A01N43/40 ,  A01N43/54 ,  A01N43/56 ,  A01N43/58 ,  A01N43/60 ,  C07D213/81 ,  C07D239/28 ,  C07D401/12

Abstract: A compound of formula (I) wherein R1 to R4 are, for example, each hydrogen, R5 is, for example, a substituted phenol; R6 is, for example, hydrogen; R7 is, for example, hydrogen, cyano, hydroxyl, formyl, C1-C4-alkyl, C1-C4-alkoxy, C2-C4-alkenyl, or C2-C4-alkynyl; and A1 to A5 is, for example, A1 is N or C—X, A3 is C—X, and A2, A4 and A5 are C—H, where X, is, for example, halogen; and its use as a pesticidal agent.

Abstract translation: 其中R 1至R 4为例如每个氢的式（I）化合物，R 5为例如取代的苯酚; R6是例如氢; R 7为例如氢，氰基，羟基，甲酰基，C 1 -C 4 - 烷基，C 1 -C 4 - 烷氧基，C 2 -C 4 - 烯基或C 2 -C 4 - 炔基; 例如A 1〜A A5为N或C-X，A3为C-X，A2，A4，A5为C-H，X为例如卤素。 并用作杀虫剂。

公开(公告)号：US09867371B2

公开(公告)日：2018-01-16

申请号：US14903169

申请日：2014-07-01

Applicant: SYNGENTA PARTICIPATIONS AG

Inventor： Anthony Cornelius O'Sullivan ,  Regis Jean Georges Mondiere ,  Olivier Loiseleur ,  Tomas Smejkal ,  Torsten Luksch ,  Andre Jeanguenat ,  Raphael Dumeunier ,  Edouard Godineau ,  Thomas Pitterna

IPC: A01N27/00 ,  A61K31/015 ,  A01N37/18 ,  C07D213/81 ,  C07D231/14 ,  C07D239/28 ,  C07C233/66 ,  C07C255/57 ,  C07C291/10 ,  C07C211/37 ,  C07C317/32 ,  C07C323/62 ,  C07C233/14 ,  C07C233/81 ,  C07C235/54 ,  C07C235/62 ,  A01N37/34 ,  A01N37/40 ,  A01N43/20 ,  A01N43/40 ,  C07C233/23 ,  C07C233/32 ,  C07C233/90 ,  C07C251/44 ,  C07C265/10 ,  C07D213/82 ,  C07D263/52 ,  C07D305/08

CPC classification number: A01N37/18 ,  A01N37/34 ,  A01N37/40 ,  A01N43/20 ,  A01N43/40 ,  C07B2200/07 ,  C07C211/37 ,  C07C233/14 ,  C07C233/23 ,  C07C233/32 ,  C07C233/66 ,  C07C233/81 ,  C07C233/90 ,  C07C235/54 ,  C07C235/62 ,  C07C251/44 ,  C07C255/57 ,  C07C265/10 ,  C07C291/10 ,  C07C317/32 ,  C07C323/62 ,  C07C2601/04 ,  C07D213/81 ,  C07D213/82 ,  C07D231/14 ,  C07D239/28 ,  C07D263/52 ,  C07D305/08

Abstract: Compounds of the formula (I), in which the substituents are as defined in claim 1, are suitable for use as nematicides.

公开(公告)号：US08987465B2

公开(公告)日：2015-03-24

申请号：US14354163

申请日：2012-10-31

Applicant: Syngenta Participations AG

Inventor： Thomas Pitterna ,  Olivier Loiseleur ,  Anthony Cornelius O'Sullivan ,  Torsten Luksch

IPC: C07D213/00 ,  A01N43/40 ,  C07D405/14 ,  A01N43/50 ,  A01N43/56 ,  A01N43/60 ,  A01N43/76 ,  A01N43/90 ,  C07D401/04 ,  C07D405/04 ,  C07D409/04 ,  C07D413/04 ,  C07D471/04 ,  C07D498/04 ,  A01N43/54 ,  A61K45/06 ,  A61K31/443 ,  A61K31/4436 ,  A61K31/4439 ,  A61K31/444 ,  A61K31/4709 ,  A61K31/497 ,  A61K31/4985 ,  A61K31/506 ,  A01N43/42 ,  A61K47/02 ,  A61K47/10 ,  A61K9/08 ,  A61K9/107 ,  A61K9/14 ,  A61K9/16

CPC classification number: A01N43/40 ,  A01N43/42 ,  A01N43/50 ,  A01N43/54 ,  A01N43/56 ,  A01N43/60 ,  A01N43/76 ,  A01N43/90 ,  A61K9/08 ,  A61K9/1075 ,  A61K9/143 ,  A61K9/145 ,  A61K9/1611 ,  A61K9/1652 ,  A61K31/443 ,  A61K31/4436 ,  A61K31/4439 ,  A61K31/444 ,  A61K31/4709 ,  A61K31/497 ,  A61K31/4985 ,  A61K31/506 ,  A61K45/06 ,  A61K47/02 ,  A61K47/10 ,  C07D401/04 ,  C07D405/04 ,  C07D405/14 ,  C07D409/04 ,  C07D413/04 ,  C07D471/04 ,  C07D498/04 ,  A61K2300/00

Abstract: A compound of formula (I) (I), wherein R1 to R4 are, for example, each hydrogen, R5 is pyridyl, which has one or more substituents at least one of which is, for example, a 5 membered heterocycle; R7 is, for example, hydrogen, cyano, hydroxyl, formyl, C1-C4-alkyl, C1-C4-alkoxy, C2-C4-alkenyl, or C2-C4-alkynyl; and A1 to A5 are, independently selected, from, for example, N, and C—H; and its use as a pesticidal agent.

Abstract translation: 式（I）（I）的化合物，其中R 1至R 4为例如各自的氢，R 5为吡啶基，其具有一个或多个取代基，其中至少一个为例如5元杂环; R 7为例如氢，氰基，羟基，甲酰基，C 1 -C 4 - 烷基，C 1 -C 4 - 烷氧基，C 2 -C 4 - 烯基或C 2 -C 4 - 炔基; 并且A1至A5独立地选自例如N和C-H; 并用作杀虫剂。