公开(公告)号：US11635382B2

公开(公告)日：2023-04-25

申请号：US16055201

申请日：2018-08-06

Applicant: SYSMEX CORPORATION

Inventor： Osamu Kikuchi ,  Takahito Mihara ,  Yuji Masuda ,  Atsushi Shirakami ,  Takuma Watanabe ,  Daigo Fukuma ,  Masaharu Shibata

IPC: G01N21/64 ,  G01N15/14 ,  G01N33/80 ,  G01N33/96 ,  G01N35/00 ,  G01N15/10 ,  G01N35/04 ,  G01N33/49 ,  G01N15/00

Abstract: A blood analyzer according to one or more embodiments may include: a specimen preparation part that prepares a measurement specimen by mixing a reagent into a blood preparation; a measurement part that measures the measurement specimen; a measurement mode selection unit that receives an input of a type of blood preparation as a measurement target selected from a plurality of types of blood preparations; and a controller. The controller may cause the specimen preparation part to prepare the measurement specimen depending on the selected type of blood preparation.

公开(公告)号：US11002746B2

公开(公告)日：2021-05-11

申请号：US16585982

申请日：2019-09-27

Applicant: Sysmex Corporation

Inventor： Yuhgi Suzuki ,  Takuma Watanabe

IPC: G01N33/80 ,  C12Q1/06 ,  G01N15/14 ,  G01N33/569 ,  G01N1/30 ,  G01N21/64 ,  G01N15/10 ,  G01N15/00

Abstract: Disclosed is a blood analyzer that includes: a sample preparation unit configured to mix a blood specimen and a fluorescent dye for staining nucleic acid to prepare a measurement sample; a light receiver configured to receive fluorescence and scattered light that are generated by light being applied to the measurement sample prepared by the sample preparation unit; and a controller programmed to determine whether or not infection with Plasmodium has occurred, on the basis of a value representing variation of a distribution of first particles in a range where single-ring form of red blood cells appear, the range where single-ring form of red blood cells appear being identified according to fluorescence intensities and scattered light intensities obtained by processing of signals from the light receiver.

公开(公告)号：US10451638B2

公开(公告)日：2019-10-22

申请号：US15657962

申请日：2017-07-24

Applicant: Sysmex Corporation

Inventor： Yuhgi Suzuki ,  Takuma Watanabe

IPC: G01N33/80 ,  G01N1/30 ,  G01N21/64 ,  G01N15/14 ,  C12Q1/06 ,  G01N33/569 ,  G01N15/00 ,  G01N15/10

Abstract: Disclosed is a blood analyzer that includes: a sample preparation unit configured to mix a blood specimen and a fluorescent dye for staining nucleic acid to prepare a measurement sample; a light receiver configured to receive fluorescence and scattered light that are generated by light being applied to the measurement sample prepared by the sample preparation unit; and a controller programmed to determine whether or not infection with Plasmodium has occurred, on the basis of a value representing variation of a distribution of first particles in a range where single-ring form of red blood cells appear, the range where single-ring form of red blood cells appear being identified according to fluorescence intensities and scattered light intensities obtained by processing of signals from the light receiver.

公开(公告)号：US10241048B2

公开(公告)日：2019-03-26

申请号：US14819027

申请日：2015-08-05

Applicant: Sysmex Corporation

Inventor： Munehisa Izuka ,  Takuma Watanabe

IPC: G01N33/00 ,  G01N31/00 ,  G01N21/64 ,  G01N33/569 ,  G01N15/14 ,  G01N21/49 ,  G01N33/49 ,  G01N15/00

Abstract: A blood analyzing method comprises irradiating light on a measurement sample prepared using fluorescent dye so as to produce a difference in fluorescence intensity between reticulocytes and mature red blood cells in a blood sample, detecting scattered light and fluorescent light given off from blood cells in the measurement sample, and obtaining fluorescence data related to the fluorescent light and scattered light data related to the scattered light for each blood cell, determining the possibility of the presence of plasmodium falciparum parasites in the blood sample based on the distribution conditions of blood cells in the reticulocyte distribution range based on the scattered light data and the fluorescent light data.