公开(公告)号：US20200264181A1

公开(公告)日：2020-08-20

申请号：US16793073

申请日：2020-02-18

Applicant: SYSMEX CORPORATION

Inventor： Yusuke TAKAHASHI ,  Masatoshi YANAGIDA ,  Kentaro SHIRAI ,  Yuichi IJIRI ,  Shigeki IWANAGA

IPC: G01N33/574 ,  G01N15/14 ,  G01N21/64

Abstract: The present invention provides a method for determining a success or failure of a measurement of a target particle contained in a measurement sample. The method includes: detecting the target particle and other particle other than the target particle in the measurement sample; and determining the success or failure of the measurement of the target particle based on at least a detection result of the other particle.

公开(公告)号：US20200173980A1

公开(公告)日：2020-06-04

申请号：US16697270

申请日：2019-11-27

Applicant: SYSMEX CORPORATION

Inventor： Yusuke TAKAHASHI ,  Kentaro SHIRAI ,  Masatoshi YANAGIDA ,  Shigeki IWANAGA ,  Yuichi IJIRI ,  Keiko YOSHIKAWA

IPC: G01N33/49 ,  B01L3/00

Abstract: A method of determining a quality of a cell separation, according to an aspect, includes: separating, by running a specimen containing a first particle and a second particle in a flow path, the specimen to a first specimen containing the first particle and a second specimen containing the second particle, based on a difference in magnitude of a force exerted on each particle contained in the specimen; measuring first information on an amount of the first specimen and second information on an amount of the second specimen; and determining a quality of the separating based on the first information and the second information.

公开(公告)号：US20190128793A1

公开(公告)日：2019-05-02

申请号：US16177671

申请日：2018-11-01

Applicant: SYSMEX CORPORATION

Inventor： Kentaro SHIRAI ,  Yusuke TAKAHASHI ,  Masatoshi YANAGIDA ,  Shigeki IWANAGA ,  Tomokazu YOSHIDA ,  Yuichi IJIRI

IPC: G01N15/14 ,  G06T7/00 ,  G06T7/70

Abstract: A cell detection method and a cell detection system capable of performing target cell detection satisfactorily without interference and reducing the time required for detection of target cells are provided. The cell detection method includes a separation step of step S1 to obtain a sample containing target cells by removing at least a part of the non-target cells from a biological sample including target cells and non-target cells based on a difference in forces acting on target cells and non-target cells; a concentration step of step S3 of obtaining a measurement sample having a target cell concentration increased from the sample containing target cells; a detection of step S4 of detecting target cells by subjecting the measurement sample to an imaging flow cytometer.

公开(公告)号：US20170152552A1

公开(公告)日：2017-06-01

申请号：US15363503

申请日：2016-11-29

Applicant: Sysmex Corporation

Inventor： Yusuke TAKAHASHI ,  Masatoshi YANAGIDA

IPC: C12Q1/68 ,  G01N21/64

CPC classification number: C12Q1/6841 ,  G01N21/6428 ,  G01N2021/6439 ,  C12Q2563/173 ,  C12Q2565/102 ,  C12Q2565/601 ,  C12Q2565/626

Abstract: Disclosed is a cell selection method including a sample preparation step of preparing a sample by performing staining of nucleic acid in each of cells by a first fluorescent dye; and hybridization with respect to an evaluation target region in DNA in each cell by an evaluation probe including a second fluorescent dye; a light receiving step of applying light to the sample and receiving fluorescence from the first fluorescent dye and fluorescence from the second fluorescent dye; and a selection step of selecting an analysis target cell on the basis of intensity of the fluorescence from the first fluorescent dye and intensity of the fluorescence from the second fluorescent dye, wherein the first fluorescent dye is a dye that emits fluorescence having a first wavelength, and the second fluorescent dye is a dye that emits fluorescence having a second wavelength different from the first wavelength.