-
公开(公告)号：US11333875B2
公开(公告)日：2022-05-17
申请号：US17141933
申请日：2021-01-05
Applicant: SamanTree Medical SA
Inventor： Etienne Shaffer , Jonathan Abel Pirolet , Frédéric Schmitt , Bastien Rachet , Diego Joss , Aurèle Timothée Horisberger
Abstract: Disclosed herein are sample dishes for use with microscopes that are simple to mount on a microscope and facilitate easy manipulation of tissue samples disposed thereon during imaging as well as methods of their use. A sample dish comprises an optical interface and, optionally, a support member that holds the optical interface. The optical interface of a sample dish is suitably transparent and planar such that a focal plane of a microscope can reside uniformly at or within a surface of a sample during imaging. In certain embodiments, a support member comprises a dish for holding excess fluid. In certain embodiments, a sample dish comprises separation ribs. In certain embodiments, a sample dish comprises one or more manipulation members (e.g., tabs). In certain embodiments, a sample dish is used with an imaging artifact reducing fluid.
-
公开(公告)号：US11181728B2
公开(公告)日：2021-11-23
申请号：US17006235
申请日：2020-08-28
Applicant: SamanTree Medical SA
Inventor： Etienne Shaffer , Bastien Rachet , Aurèle Timothée Horisberger , Jonathan Abel Pirolet , Diego Joss , Andrey Naumenko , Frédéric Schmitt
IPC: G02B21/06 , G02B21/36 , G02B21/00 , A61B90/20 , G01N21/64 , G02B21/08 , G02B21/16 , H04N5/225 , H04N7/18
Abstract: Disclosed herein are systems for imaging of samples using an array of micro optical elements and methods of their use. In some embodiments, an optical chip comprising an array of micro optical elements moves relative to an imaging window and a detector in order to scan over a sample to produce an image. A focal plane can reside within a sample or on its surface during imaging. Detecting optics are used to detect back-emitted light collected by an array of micro optical elements that is generated by an illumination beam impinging on a sample. In some embodiments, an imaging system has a large field of view and a large optical chip such that an entire surface of a sample can be imaged quickly. In some embodiments, a sample is accessible by a user during imaging due to the sample being exposed while disposed on or over an imaging window.
-
公开(公告)号：US10928621B2
公开(公告)日：2021-02-23
申请号：US16146518
申请日：2018-09-28
Applicant: SamanTree Medical SA
Inventor： Etienne Shaffer , Jonathan Abel Pirolet , Frédéric Schmitt , Bastien Rachet , Diego Joss , Aurèle Timothée Horisberger
Abstract: Disclosed herein are sample dishes for use with microscopes that are simple to mount on a microscope and facilitate easy manipulation of tissue samples disposed thereon during imaging as well as methods of their use. A sample dish comprises an optical interface and, optionally, a support member that holds the optical interface. The optical interface of a sample dish is suitably transparent and planar such that a focal plane of a microscope can reside uniformly at or within a surface of a sample during imaging. In certain embodiments, a support member comprises a dish for holding excess fluid. In certain embodiments, a sample dish comprises separation ribs. In certain embodiments, a sample dish comprises one or more manipulation members (e.g., tabs). In certain embodiments, a sample dish is used with an imaging artifact reducing fluid.
-
公开(公告)号：US12236603B2
公开(公告)日：2025-02-25
申请号：US17174919
申请日：2021-02-12
Applicant: SamanTree Medical SA
Inventor： Andrey Naumenko , Aurèle Timothée Horisberger , Diego Joss , Frédéric Schmitt , Etienne Shaffer , Jonathan Abel Pirolet , Bastien Rachet , Andrew Logvinov
IPC: G06T7/00 , G01N33/483 , G02B21/00 , G02B21/36 , G06T3/4038
Abstract: Systems and methods to identify and/or reduce or eliminate sample motion artifacts are disclosed. Sample motion artifacts may be reduced or eliminated using scan patterns where an acquisition time difference between when perimeter pixels in adjacent tiles are acquired is reduced, as compared to a conventional raster scan to reduce or eliminate discontinuities that would otherwise appear at tile boundaries in an image. In some embodiments, test images acquired using relatively small test scan patterns or intensities of test points acquired at different times may be compared to determine whether sample motion has occurred. In some embodiments, intensity of adjacent pixels at a tile boundary are compared. In some embodiments, intensity of one or more single pixels is monitored over time to determine whether sample motion has occurred over a period of time. In some embodiments, a flattening or reshaping tool may be used to suppress sample motion during imaging.
-
公开(公告)号：US20220269059A1
公开(公告)日：2022-08-25
申请号：US17739612
申请日：2022-05-09
Applicant: SamanTree Medical SA
Inventor： Etienne Shaffer , Jonathan Abel Pirolet , Frédéric Schmitt , Bastien Rachet , Diego Joss , Aurèle Timothée Horisberger
Abstract: Disclosed herein are sample dishes for use with microscopes that are simple to mount on a microscope and facilitate easy manipulation of tissue samples disposed thereon during imaging as well as methods of their use. A sample dish comprises an optical interface and, optionally, a support member that holds the optical interface. The optical interface of a sample dish is suitably transparent and planar such that a focal plane of a microscope can reside uniformly at or within a surface of a sample during imaging. In certain embodiments, a support member comprises a dish for holding excess fluid. In certain embodiments, a sample dish comprises separation ribs. In certain embodiments, a sample dish comprises one or more manipulation members (e.g., tabs). In certain embodiments, a sample dish is used with an imaging artifact reducing fluid.
-
Patent Agency Ranking
公开(公告)号：US20200033581A1
公开(公告)日：2020-01-30
申请号：US16593726
申请日：2019-10-04
Applicant: SamanTree Medical SA
Inventor： Etienne Shaffer , Bastien Rachet , Aurèle Timothée Horisberger , Jonathan Abel Pirolet , Diego Joss , Andrey Naumenko , Frédéric Schmitt
Abstract: Disclosed herein are systems for imaging of samples using an array of micro optical elements and methods of their use. In some embodiments, an optical chip comprising an array of micro optical elements moves relative to an imaging window and a detector in order to scan over a sample to produce an image. A focal plane can reside within a sample or on its surface during imaging. Detecting optics are used to detect back-emitted light collected by an array of micro optical elements that is generated by an illumination beam impinging on a sample. In some embodiments, an imaging system has a large field of view and a large optical chip such that an entire surface of a sample can be imaged quickly. In some embodiments, a sample is accessible by a user during imaging due to the sample being exposed while disposed on or over an imaging window.
-
公开(公告)号：US20250148606A1
公开(公告)日：2025-05-08
申请号：US19011901
申请日：2025-01-07
Applicant: SamanTree Medical SA
Inventor： Andrey Naumenko , Aurèle Timothée Horisberger , Diego Joss , Frédéric Schmitt , Etienne Shaffer , Jonathan Abel Pirolet , Bastien Rachet , Andrew Logvinov
IPC: G06T7/00 , G01N33/483 , G02B21/00 , G02B21/36 , G06T3/4038
Abstract: Systems and methods to identify and/or reduce or eliminate sample motion artifacts are disclosed. Sample motion artifacts may be reduced or eliminated using scan patterns where an acquisition time difference between when perimeter pixels in adjacent tiles are acquired is reduced, as compared to a conventional raster scan to reduce or eliminate discontinuities that would otherwise appear at tile boundaries in an image. In some embodiments, test images acquired using relatively small test scan patterns or intensities of test points acquired at different times may be compared to determine whether sample motion has occurred. In some embodiments, intensity of adjacent pixels at a tile boundary are compared. In some embodiments, intensity of one or more single pixels is monitored over time to determine whether sample motion has occurred over a period of time. In some embodiments, a flattening or reshaping tool may be used to suppress sample motion during imaging.
-
公开(公告)号：US20240264422A1
公开(公告)日：2024-08-08
申请号：US18607993
申请日：2024-03-18
Applicant: SamanTree Medical SA
Inventor： Etienne Shaffer , Jonathan Abel Pirolet , Frédéric Schmitt , Bastien Rachet , Diego Joss , Aurèle Timothée Horisberger
CPC classification number: G02B21/34 , G01N21/01 , G01N21/6428 , G02B21/367
Abstract: Disclosed herein are sample dishes for use with microscopes that are simple to mount on a microscope and facilitate easy manipulation of tissue samples disposed thereon during imaging as well as methods of their use. A sample dish comprises an optical interface and, optionally, a support member that holds the optical interface. The optical interface of a sample dish is suitably transparent and planar such that a focal plane of a microscope can reside uniformly at or within a surface of a sample during imaging. In certain embodiments, a support member comprises a dish for holding excess fluid. In certain embodiments, a sample dish comprises separation ribs. In certain embodiments, a sample dish comprises one or more manipulation members (e.g., tabs). In certain embodiments, a sample dish is used with an imaging artifact reducing fluid.
-
公开(公告)号：US10816788B2
公开(公告)日：2020-10-27
申请号：US16593726
申请日：2019-10-04
Applicant: SamanTree Medical SA
Inventor： Etienne Shaffer , Bastien Rachet , Aurèle Timothée Horisberger , Jonathan Abel Pirolet , Diego Joss , Frédéric Schmitt
IPC: G01J3/46 , G02B21/36 , G02B21/00 , A61B90/20 , G01N21/64 , G02B21/08 , G02B21/16 , H04N5/225 , H04N7/18
Abstract: Disclosed herein are systems for imaging of samples using an array of micro optical elements and methods of their use. In some embodiments, an optical chip comprising an array of micro optical elements moves relative to an imaging window and a detector in order to scan over a sample to produce an image. A focal plane can reside within a sample or on its surface during imaging. Detecting optics are used to detect back-emitted light collected by an array of micro optical elements that is generated by an illumination beam impinging on a sample. In some embodiments, an imaging system has a large field of view and a large optical chip such that an entire surface of a sample can be imaged quickly. In some embodiments, a sample is accessible by a user during imaging due to the sample being exposed while disposed on or over an imaging window.
-
公开(公告)号：US20190129158A1
公开(公告)日：2019-05-02
申请号：US16146518
申请日：2018-09-28
Applicant: SamanTree Medical SA
Inventor： Etienne Shaffer , Jonathan Abel Pirolet , Frédéric Schmitt , Bastien Rachet , Diego Joss
Abstract: Disclosed herein are sample dishes for use with microscopes that are simple to mount on a microscope and facilitate easy manipulation of tissue samples disposed thereon during imaging as well as methods of their use. A sample dish comprises an optical interface and, optionally, a support member that holds the optical interface. The optical interface of a sample dish is suitably transparent and planar such that a focal plane of a microscope can reside uniformly at or within a surface of a sample during imaging. In certain embodiments, a support member comprises a dish for holding excess fluid. In certain embodiments, a sample dish comprises separation ribs. In certain embodiments, a sample dish comprises one or more manipulation members (e.g., tabs). In certain embodiments, a sample dish is used with an imaging artifact reducing fluid.
-
-
-
-
-
-
-
-
-
Search Results
20
records
(took 0.013 seconds)
