公开(公告)号：US20140095128A1

公开(公告)日：2014-04-03

申请号：US14039577

申请日：2013-09-27

Applicant: Samsung Electronics Co., Ltd.

Inventor： Misook HA

IPC: G06F19/16 ,  G06F19/12

CPC classification number: G16B15/00 ,  G16B5/00 ,  G16B40/00

Abstract: Provided is a method of predicting a DNA structure by predicting the distribution of a nucleosome in a DNA sequence using a specificity of a nucleosome, and a method of determining a position of a nucleosome in DNA sequence by predicting the position using a specificity of a nucleosome.

Abstract translation: 提供了通过使用核小体的特异性预测DNA序列中的核小体的分布来预测DNA结构的方法，以及通过使用核小体的特异性预测位置来确定DNA序列中的核小体的位置的方法 。

公开(公告)号：US20160378911A1

公开(公告)日：2016-12-29

申请号：US15196656

申请日：2016-06-29

Applicant: SAMSUNG ELECTRONICS CO., LTD. ,  KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Misook HA ,  Kwang-Hyun CHO ,  Sung-Hwan CHO ,  Sang-Min PARK ,  Ho-Sung LEE ,  Hwang-Yeol LEE

IPC: G06F19/12 ,  G06F19/28 ,  C40B30/02

CPC classification number: G16B5/00 ,  G16B35/00 ,  G16C20/60

Abstract: An exemplary embodiment of the invention provides a discovery method of a protein which serves as a target of a target therapy, including: performing an attractor analysis on a first body signal transferring network of a cancer cell that is perturbed, and determining at least one of a plurality of proteins included in a third body signal transferring network of a cancer cell as a target protein based on the attractor analysis on the first body signal transferring network and an attractor analysis on a second body signal transferring network of a normal cell.

Abstract translation: 本发明的一个示例性实施方案提供了用作目标疗法靶标的蛋白质的发现方法，包括：对被扰动的癌细胞的第一身体信号传递网络进行吸引子分析，以及确定至少一种 基于第一身体信号传递网络上的吸引子分析和在正常小区的第二身体信号传送网络上的吸引子分析，包括在作为靶蛋白的癌细胞的第三身体信号传递网络中的多个蛋白质。

公开(公告)号：US20160055294A1

公开(公告)日：2016-02-25

申请号：US14615182

申请日：2015-02-05

Applicant: SAMSUNG ELECTRONICS CO., LTD.

Inventor： Misook HA ,  Sungjin KIM

IPC: G06F19/20 ,  G06F19/22

CPC classification number: G16B25/00 ,  G16B5/00

Abstract: A method and an apparatus for determining a transcription factor for a biological process are provided. The method of determining a transcription factor involves obtaining N items of expression data related to gene information, selecting M items of expression data based on similarities of the N items of expression data, and forming the selected M items of expression data as a first group using a processor, comparing the expression data of the first group to expression data of a plurality of transcription factors, and identifying at least one transcription factor having a relatively high similarity to the first group, among the transcription factors, in which M is a natural number less than or equal to N.

Abstract translation: 提供了一种用于确定生物过程的转录因子的方法和装置。 确定转录因子的方法包括获得与基因信息相关的N个表达数据项，基于表达数据的N个项目的相似性选择M个表达数据项，以及使用所选择的M个表达数据项作为第一组，使用 处理器，将第一组的表达数据与多个转录因子的表达数据进行比较，并鉴定其中M为自然数的转录因子中至少一个与第一组相似性较高的转录因子 小于或等于N.