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公开(公告)号：US11729536B2
公开(公告)日：2023-08-15
申请号：US16967338
申请日：2019-01-21
Applicant: Sartorius Stedim Biotech GmbH
Inventor： Christian Grimm , Jochen Scholz , Matthias Bode , Andreas Prediger , Patrick Courtney
CPC classification number: H04Q9/00 , H05K1/0274 , H05K2201/10106
Abstract: Summarizing the invention, a sensing element for monitoring the state of a single-use sterilizable element such as a single-use bioreactor, wherein the state of the single-use sterilizable element is determined by at least one environmental condition is provided. The sensing element comprises: a variable component having at least one physical property that is configured to change in response to the at least one environmental condition and/or a change thereof, wherein the variable component comprises a sensing material with changing absorption characteristics for electromagnetic radiation configured to change in response to the at least one environmental condition and/or a change thereof.
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Patent Agency Ranking
公开(公告)号：US12179184B2
公开(公告)日：2024-12-31
申请号：US17419572
申请日：2019-12-19
Applicant: Sartorius Stedim Biotech GmbH
Inventor： Christian Grimm , Jochen Scholz , Matthias Bode
Abstract: A device for compensating short-term pressure or volume fluctuations of a medium in a continuously managed biopharmaceutical process including a receiving space in fluid communication with a process line through which a medium flows, an equalizing space, which is separated from the receiving space by a deflectable element, and a counter-pressure mechanism in the equalizing space for applying a counter-pressure to the deflectable element towards the receiving space. A method of compensating short-term pressure or volume fluctuations of a medium in a continuously managed biopharmaceutical process including providing a receiving space in fluid communication with a process line through which a medium flows, receiving an excess amount of the medium flowing into the receiving space, charging an energy storage device by the medium flowing into the receiving space, and expelling at least part of the excess amount if the pressure or flow rate falls below a set amount.
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公开(公告)号：US20230077918A1
公开(公告)日：2023-03-16
申请号：US17800469
申请日：2020-11-27
Applicant: Sartorius Stedim Biotech GmbH
Inventor： Matthias Bode , Swen Weitemeier , Alexander Zilaev , Manuel Juenemann , Anne-Lise Damiano , Bernhard Diel
Abstract: A bioprocessing installation comprising a reservoir tank, one or more fluid lines, one or more receiving containers and an electronic control unit. The fluid line fluidically connects the reservoir tank to a receiving container. The liquid biological medium can be transferred from the reservoir tank through the fluid line into the at least one receiving container. The bioprocessing installation comprises a sensor arrangement with at least one gas bubble sensor, which sensor arrangement is configured to detect one or more gas bubbles or foam or separated phases in the liquid biological medium by a gas bubble sensor and to generate one or more corresponding sensor signals, and the electronic control unit is configured to monitor the transfer of the liquid biological medium from the reservoir tank in the direction of the at least one receiving container based on the sensor signals generated by the sensor arrangement.
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公开(公告)号：US20210037297A1
公开(公告)日：2021-02-04
申请号：US16967338
申请日：2019-01-21
Applicant: Sartorius Stedim Biotech GmbH
Inventor： Christian Grimm , Jochen Scholz , Matthias Bode , Andreas Prediger , Patrick Courtney
Abstract: Summarizing the invention, a sensing element for monitoring the state of a single-use sterilizable element such as a single-use bioreactor, wherein the state of the single-use sterilizable element is determined by at least one environmental condition is provided. The sensing element comprises: a variable component having at least one physical property that is configured to change in response to the at least one environmental condition and/or a change thereof, wherein the variable component comprises a sensing material with changing absorption characteristics for electromagnetic radiation configured to change in response to the at least one environmental condition and/or a change thereof.
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公开(公告)号：US20220162538A1
公开(公告)日：2022-05-26
申请号：US17441136
申请日：2020-03-19
Applicant: Sartorius Stedim Biotech GmbH
Inventor： Christian Grimm , Andreas Prediger , Matthias Bode , Arkadiusz Pajak
Abstract: A container for storing, mixing and/or cultivating a medium, in particular a bioreactor for a medium, comprises a line system as a discharge line, feed line and/or bypass line of the bioreactor. The system can comprise a line body formed as a single piece for a medium to flow therethrough. The has a first and a second connection region for connecting in particular to the container and/or the line system and at least a first and a second coupling apparatus in the region between the connection regions.
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公开(公告)号：US20220143619A1
公开(公告)日：2022-05-12
申请号：US17442866
申请日：2020-01-15
Applicant: Sartorius Stedim Biotech GmbH
Inventor： Matthias Bode , Christian Grimm , Thorsten Adams , Jens Rupprecht
Abstract: A sensor positioning system for a bioprocess engineering unit, wherein a container is provided for receiving a biological medium which, when installed, extends in the axial direction from an upper container end to a lower container end, wherein a holder is provided for holding the container when installed, wherein a sensor is provided for fixing to the container. A positioning aid device for positioning the sensor to be fixed is provided on the container, the positioning aid device has a positioning aid that can be applied directly to or near the container on the holder, which can be brought into different vertical positions and/or circumferential positions relative to at least one reference point provided on the container and/or holder, and the positioning aid device has a technical storage medium or analog print medium with an allocation list.
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