Instruments for analyzing binding assays based on attenuation of light by thin films
    1.
    发明授权
    Instruments for analyzing binding assays based on attenuation of light by thin films 失效
    用于分析基于薄膜衰减光的结合测定的仪器

    公开(公告)号:US06483585B1

    公开(公告)日:2002-11-19

    申请号:US09633036

    申请日:2000-08-04

    Applicant: Shao Yang

    Inventor: Shao Yang

    CPC classification number: G01B11/065 G01N21/211

    Abstract: A modified and improved polarizier ellipsometer allows for improved signal quality and signal to noise performance. This improvement is based on rotating one polarizer relative to the other fixed polarizer to generate AC mode signals related to a thin film under analysis. The AC mode signal may be compared to a background signal and the ratio of sample signal to background signal used to provide a more accurate assessment of film thickness. The normalized AC signal for an unknown thickness may be compared to a standard curve generated for a film of similar optical properties for an exact thickness determination or may be used directly to report a relative thickness value. Other modifications of the improved polarizer ellipsometer of the invention are also described where one or both of the fixed polarizers are removed to improve the signal intensity through reduction of the number of optical components. These modifications are designed to address specific thin film and substrate combinations.

    Abstract translation: 改进和改进的偏振椭偏仪允许改善信号质量和信噪比性能。 这种改进是基于相对于另一个固定的偏振器旋转一个偏振器而产生与分析的薄膜相关的AC模式信号。 AC模式信号可以与背景信号进行比较,并且采样信号与背景信号的比率用于提供更准确的膜厚度评估。 可以将未知厚度的归一化AC信号与用于精确厚度确定的类似光学性质的膜产生的标准曲线进行比较,或者可以直接用于报告相对厚度值。 还描述了本发明的改进的偏振器椭偏仪的其它修改,其中一个或两个固定偏振器被去除以通过减少光学部件的数量来改善信号强度。 这些修改旨在解决特定的薄膜和基板组合。

    Photoplethysmographic instrument having an integrated multimode optical
coupler device
    3.
    发明授权
    Photoplethysmographic instrument having an integrated multimode optical coupler device 失效
    光电体积描记器具具有集成的多模光耦合器件

    公开(公告)号:US5790729A

    公开(公告)日:1998-08-04

    申请号:US631314

    申请日:1996-04-10

    Abstract: The integrated multimode optical coupling apparatus comprises an N-to-M optical coupling arrangement that is simple to manufacture, minimizes optical losses and is significantly less expensive than the prior art arrangements of coupling optical signals. The preferred embodiment of the apparatus of the present invention comprises a substrate into which is formed a plurality of optical channels, each of which is joined at one end into a single output optical channel. This integrated optical coupler is formed by diffusing silver ions or other equivalent ions into the glass substrate in these defined areas to form channels of high optical refractive index in the body of the substrate. At one end of each of the optical channels that are formed in the substrate, the plurality of the optical channels are joined together in a volumetric region of the substrate wherein the individual channels merge into one unified common structure. The output optical channels are joined to this combiner to thereby carry the combined light output to the output terminals. One application of this apparatus is in the field of photoplethysmography, such as in a pulse oximeter instrument.

    Abstract translation: 该集成多模光耦合装置包括一种N-to-M光耦合装置,其易于制造,使光损耗最小化,并且比现有技术的耦合光信号的布置明显更便宜。 本发明装置的优选实施例包括一个衬底,其中形成有多个光通道,每个光通道在一端连接成单个输出光通道。 该集成光耦合器通过在这些限定区域中将银离子或其它等效离子扩散到玻璃衬底中而形成,以在衬底的主体中形成具有高光折射率的沟道。 在形成在基板中的每个光通道的一端,多个光通道在基板的体积区域中连接在一起,其中各个通道合并为一个统一的公共结构。 输出光通道连接到该组合器,从而将组合的光输出传送到输出端。 该装置的一个应用是在光体积描记术领域,例如在脉搏血氧仪中。

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