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公开(公告)号：US20240241048A1
公开(公告)日：2024-07-18
申请号：US18413139
申请日：2024-01-16
Inventor： Tao FANG , Yong DAI , Lihua ZHOU , Yun HE
IPC: G01N21/47
CPC classification number: G01N21/47 , G01N2201/06
Abstract: Sample analyzers and a method for controlling the sample analyzer are provided. The sample analyzer includes a reaction device, a detection device, a processor and a display. The reaction device is configured to obtain a reaction product. Multiple types of emitting lights are emitted after the irradiation light from the detection device irradiates the reaction product. An optical signal acquisition component is configured to acquire, in each light acquiring period, optical signals corresponding to a detection wavelength and at least one wavelength other than the detection wavelength for at least one type of emitting light. The processor is configured to calculate, for the at least one type of emitting light, optical data corresponding to the detection wavelength and the at least one wavelength other than the detection wavelength in each light acquiring period. The display is configured to display the optical data in multiple light acquiring periods.
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公开(公告)号：US20240085331A1
公开(公告)日：2024-03-14
申请号：US18389125
申请日：2023-11-13
Inventor： Qiushi YI , Dongsheng WANG , Yong DAI
CPC classification number: G01N21/6486 , G01N21/47 , G01N33/487
Abstract: An optical detection system, a blood cell analyzer and a platelet detection method are provided. The optical detection system includes: an optical subsystem, a flow chamber and a first detector; the optical subsystem includes a laser, a front optical assembly including an optical isolator, and a rear optical assembly including a blocking diaphragm. The laser is configured to emit a laser beam; the front optical assembly is configured to perform front optical treatment; the rear optical assembly is disposed downstream of the flow chamber in the propagation direction of the laser beam, and is configured to perform rear optical treatment on the scattered light and the laser beam converged at the blocking diaphragm; and the optical isolator is configured to isolate reflected light that is generated when the laser beam passes through the flow chamber.
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公开(公告)号：US20220099553A1
公开(公告)日：2022-03-31
申请号：US17644074
申请日：2021-12-13
Inventor： Xiansuan DU , Yong DAI
Abstract: A sample analyzer with an optical detection device and a sample analysis method of the sample analyzer are disclosed. The optical detection device includes a fluid chamber, a light source and a light detector. The fluid chamber includes an illumination zone. An analyte flows through the illumination zone so as to form a sample stream. The light source illuminates the illumination zone to excite cell articles, reacted with a reagent, of the sample stream to emit a light signal. The light detector detects the fluorescent lights and transforms it into an electric signal. The light detector can include a silicon photomultiplier.
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公开(公告)号：US20200225257A1
公开(公告)日：2020-07-16
申请号：US16727810
申请日：2019-12-26
Inventor： Qiushi YI , Zixian XIE , Yong DAI
Abstract: A sample analyzer, comprising a reaction assembly and a detection assembly, wherein the reaction assembly comprises a sampler and a reaction tank, the sampler is used for collecting a biological sample and injecting the biological sample into the reaction tank, a wall of the reaction tank is provided with a first through-hole used for injecting a first reagent, and a center line of the first through-hole is arranged to be misaligned with the sampler after the sampler moves into the reaction tank, the detection assembly is connected to the reaction tank and is used for drawing fluid from the reaction tank for test. The reaction assembly enables a solution to be more uniformly mixed.
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公开(公告)号：US20190219495A1
公开(公告)日：2019-07-18
申请号：US16224532
申请日：2018-12-18
Inventor： Xiansuan DU , Yong DAI
CPC classification number: G01N15/1434 , G01N15/1459 , G01N21/4738 , G01N21/6428 , G01N2015/0076 , G01N2015/0084 , G01N2015/1006 , G01N2015/1402 , G01N2201/06113 , G01N2201/124
Abstract: A sample analyzer with an optical detection device and a sample analysis method of the sample analyzer are disclosed. The optical detection device includes a fluid chamber, a light source and a light detector. The fluid chamber includes an illumination zone. An analyte flows through the illumination zone so as to form a sample stream. The light source illuminates the illumination zone to excite cell articles, reacted with a reagent, of the sample stream to emit a light signal. The light detector detects the fluorescent lights and transforms it into an electric signal. The light detector can include a silicon photomultiplier.
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Patent Agency Ranking
公开(公告)号：US20210148809A1
公开(公告)日：2021-05-20
申请号：US17136871
申请日：2020-12-29
Inventor： Xiansuan DU , Yong DAI
Abstract: A sample analyzer with an optical detection device and a sample analysis method of the sample analyzer are disclosed. The optical detection device includes a fluid chamber, a light source and a light detector. The fluid chamber includes an illumination zone. An analyte flows through the illumination zone so as to form a sample stream. The light source illuminates the illumination zone to excite cell articles, reacted with a reagent, of the sample stream to emit a light signal. The light detector detects the fluorescent lights and transforms it into an electric signal. The light detector can include a silicon photomultiplier.
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公开(公告)号：US20170315046A1
公开(公告)日：2017-11-02
申请号：US15163541
申请日：2016-05-24
Inventor： Xiansuan DU , Yong DAI
CPC classification number: G01N15/1434 , G01N15/1459 , G01N21/4738 , G01N21/6428 , G01N2015/0076 , G01N2015/0084 , G01N2015/1006 , G01N2015/1402 , G01N2201/06113 , G01N2201/124
Abstract: A sample analyzer with an optical detection device and a sample analysis method of the sample analyzer are disclosed. The optical detection device includes a fluid chamber, a light source and a light detector. The fluid chamber includes an illumination zone. An analyte flows through the illumination zone so as to form a sample stream. The light source illuminates the illumination zone to excite cell articles, reacted with a reagent, of the sample stream to emit a light signal. The light detector detects the fluorescent lights and transforms it into an electric signal. The light detector can include a silicon photomultiplier.
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公开(公告)号：US20240295577A1
公开(公告)日：2024-09-05
申请号：US18661557
申请日：2024-05-10
Inventor： Qiushi YI , Zixian XIE , Yong DAI
CPC classification number: G01N35/1016 , G01N1/38 , G01N35/1002
Abstract: A sample analyzer, comprising a reaction assembly and a detection assembly, wherein the reaction assembly comprises a sampler and a reaction tank, the sampler is used for collecting a biological sample and injecting the biological sample into the reaction tank, a wall of the reaction tank is provided with a first through-hole used for injecting a first reagent, and a center line of the first through-hole is arranged to be misaligned with the sampler after the sampler moves into the reaction tank, the detection assembly is connected to the reaction tank and is used for drawing fluid from the reaction tank for test. The reaction assembly enables a solution to be more uniformly mixed.
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公开(公告)号：US20220268703A1
公开(公告)日：2022-08-25
申请号：US17706268
申请日：2022-03-28
Inventor： Qiushi YI , Dongsheng WANG , Yong DAI
Abstract: An optical detection system, a blood cell analyzer and a platelet detection method are provided. The optical detection system includes: an optical subsystem, a flow chamber and a first detector; the optical subsystem includes a laser, a front optical assembly including an optical isolator, and a rear optical assembly including a blocking diaphragm. The laser is configured to emit a laser beam; the front optical assembly is configured to perform front optical treatment; the rear optical assembly is disposed downstream of the flow chamber in the propagation direction of the laser beam, and is configured to perform rear optical treatment on the scattered light and the laser beam converged at the blocking diaphragm; and the optical isolator is configured to isolate reflected light that is generated when the laser beam passes through the flow chamber.
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公开(公告)号：US20220082551A1
公开(公告)日：2022-03-17
申请号：US17537265
申请日：2021-11-29
Inventor： Yong DAI , Qiushi YI , Zhonggang LIU
Abstract: Disclosed are a sample analyzing method and a sample analyzer for measuring red blood cells and platelets. The method includes: preparing a first test sample solution containing a blood sample and a diluent; using an impedance method to acquire a first measurement result of red blood cells and platelets; when the first measurement result indicates that the blood sample is abnormal, preparing a second test sample solution containing the blood sample and a diluent or preparing a second test sample solution from the first test sample solution; irradiating the second test sample solution with light; collecting scattered light signals generated by particles in the second test sample solution; and acquiring a second measurement result of red blood cells and platelets in the second test sample solution based on the scattered light signals. Thus, RBC and PLT can be accurately classified especially under a condition of using an ordinary diluent.
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