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公开(公告)号：US20220033870A1
公开(公告)日：2022-02-03
申请号：US17426610
申请日：2020-01-30
Applicant: Spiber Inc.
Inventor： Kenji NAKAHIGASHI , Li JIANG , Takanobu NODA , Kenji TSUYAMA
Abstract: The present invention relates to a production method for a recombinant protein, the production method including a growth reduction step of reducing cell growth of recombinant cells which express a recombinant protein and a production step of producing the recombinant protein by culturing the recombinant cells in a protein production culture medium in a state of reducing the cell growth, in which the cell growth of the recombinant cells is reduced in the growth reduction step by using recombinant cells having at least one modified morphogenetic regulator as the recombinant cells.
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