公开(公告)号：US3241432A

公开(公告)日：1966-03-22

申请号：US23430862

申请日：1962-10-31

Applicant: TECHNICON INSTR

Inventor： SKEGGS LEONARD T ,  WHITEHEAD EDWIN C ,  SMYTHE WILLIAM J ,  PELAVIN MILTON H

IPC: G01N35/08

CPC classification number: G01N35/08 ,  Y10T436/118339 ,  Y10T436/144444 ,  Y10T436/171538 ,  Y10T436/204998

公开(公告)号：US3074699A

公开(公告)日：1963-01-22

申请号：US76786958

申请日：1958-10-17

Applicant: TECHNICON INSTR

Inventor： SKEGGS LEONARD T ,  GERALD KESSLER

IPC: G01N1/28 ,  G01N33/483 ,  G01N33/487

CPC classification number: G01N1/28 ,  Y10S128/03

公开(公告)号：US3098719A

公开(公告)日：1963-07-23

申请号：US3658360

申请日：1960-06-16

Applicant: TECHNICON INSTR

Inventor： SKEGGS LEONARD T

IPC: B01D33/04 ,  G01N31/02 ,  G01N35/08

CPC classification number: G01N35/08 ,  B01D33/04 ,  B01D33/333 ,  B01D33/745 ,  G01N31/02 ,  Y10T436/110833 ,  Y10T436/25375

公开(公告)号：US2946665A

公开(公告)日：1960-07-26

申请号：US61229956

申请日：1956-09-26

Applicant: TECHNICON INSTR

Inventor： SKEGGS LEONARD T

IPC: G01N7/00 ,  G01N7/14 ,  G01N31/00 ,  G01N33/483

CPC classification number: G01N7/14 ,  G01N7/00 ,  G01N33/4925 ,  Y10T436/118339

公开(公告)号：US3167397A

公开(公告)日：1965-01-26

申请号：US19742162

申请日：1962-05-24

Applicant: TECHNICON INSTR

Inventor： SKEGGS LEONARD T ,  STUART BLANCHE R

IPC: B01L9/00 ,  F04B43/12 ,  G01N1/18 ,  G01N35/08

CPC classification number: G01N1/18 ,  B01L9/00 ,  F04B43/1223 ,  G01N35/08

公开(公告)号：US3699004A

公开(公告)日：1972-10-17

申请号：US3699004D

申请日：1970-08-31

Applicant: TECHNICON INSTR

Inventor： SKEGGS LEONARD T

IPC: G01N33/483 ,  G01N35/08 ,  G01N31/14

CPC classification number: G01N35/08 ,  Y10T436/118339

Abstract: NEW AND IMPROVED METHOD AND APPARATUS FOR THE FULLY AUTOMATIC, HIGHLY ACCURATE QUANTITATIVE ANALYSIS OF A SERIES OF SAMPLES WITH REGARD TO A CONSTITUENT THEREOF ON A CONTINUOUS FLOW BASIS THROUGH RATE REACTION DETERMINATION ARE PROVIDED AND ARE OPERABLE THROUGH THE CONTINUOUS MIXING OF SAID SAMPLES AND A SUITABLE REACTANT IN CONSTANT PROPORTION, AND THE FLOW OF THE RESULTANT SAMPLE-REACTANT MIXTURES BY PUMPING ON A CONTINUOUS BASIS THROUGH REACTION PROMOTING MEANS TO PROMOTE THE SAMPLE CONSTITUENT-REACTANT RATE REACTION IN SUCH MANNER THAT DIFFERENT PORTIONS OF EACH OF THE SAMPLE-REACTANT MIXTURES ARE REACTED FOR DIFFERENT TIMES TO EFFECT A DIFFERENTIAL IN A CHARACTERISTIC OF SAID MIXTURES AS DEVELOPED AS A RESULT OF SAID REACTION. FOLLOWING THIS, THE THUSLY REACTED SAMPLE-REACTANT MIXTURE PORTIONS ARE FLOWED THROUGH DETECTOR MEANS FOR DETECTION OF SAID CHARACTERISTIC DIFFERENTIAL AND RESULTANT PROVISION OF AND OUTPUT SIGNAL WHICH IS INDICATIVE OF THE SAMPLE CONSTITUENT QUANTITY OF INTEREST. SUBSTANTIALLY HYPERBOLIC VARIATION IN THE FLOW RATE OF EACH OF SAID SAMPLE-REACTANT MIXTURES THROUGH SAID REACTION PROMOTING MEANS IS UTILIZED TO PROVIDE FOR THE DIFFERENT SAMPLE-REACTANT MIXTURE PORTION REACTION TIMES. AS SPECIFICALLY DISCLOSED HEREIN, THE METHOD AND APPARATUS OF THE INVENTION ARE PARTICULARLY ADAPTABLE TO THE ANALYSIS OF A SERIES OF BLOOD SAMPLES WITH REGARD TO AN ENZYME CONSTITUENT THEREOF.

公开(公告)号：US3320148A

公开(公告)日：1967-05-16

申请号：US15658361

申请日：1961-12-04

Applicant: TECHNICON INSTR

Inventor： SKEGGS LEONARD T

IPC: C25B7/00 ,  G01N27/447

CPC classification number: G01N27/44782 ,  C25B7/00 ,  G01N27/44756 ,  G01N27/4476 ,  G01N27/44769

公开(公告)号：US3231181A

公开(公告)日：1966-01-25

申请号：US10443761

申请日：1961-04-20

Applicant: TECHNICON INSTR

Inventor： SKEGGS LEONARD T

IPC: B01D17/02 ,  B04B1/00 ,  B04B1/02 ,  B04B5/00 ,  B04B5/04 ,  B04B5/06 ,  B04B13/00

CPC classification number: B04B1/00 ,  B01D17/0217 ,  B04B1/02 ,  B04B5/00 ,  B04B5/04 ,  B04B5/06 ,  B04B13/00

公开(公告)号：US3024692A

公开(公告)日：1962-03-13

申请号：US74153358

申请日：1958-06-12

Applicant: TECHNICON INSTR

Inventor： SKEGGS LEONARD T

IPC: G01N21/27

CPC classification number: G01N21/27

公开(公告)号：US3464794A

公开(公告)日：1969-09-02

申请号：US3464794D

申请日：1966-02-23

Applicant: TECHNICON INSTR

Inventor： ISREELI JACK ,  SKEGGS LEONARD T

IPC: G01N35/08 ,  G01N31/00 ,  G01N21/02

CPC classification number: G01N35/08 ,  Y10T436/118339 ,  Y10T436/144444 ,  Y10T436/171538 ,  Y10T436/193333