公开(公告)号：US20230293474A1

公开(公告)日：2023-09-21

申请号：US18093840

申请日：2023-01-06

Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM

Inventor： James B. BRUGAROLAS ,  Haley HILL ,  Tao WANG

IPC: A61K31/275 ,  G01N33/50

CPC classification number: A61K31/275 ,  G01N33/5044 ,  G01N33/5011 ,  A61K45/06

Abstract: The present disclosure provides methods of identifying patients who have partial or total resistance to HIF-2 inhibitors or who develop partial or total resistance to HIF-2 inhibitors after treatment and providing suitable treatment to these patients.

公开(公告)号：US20210085634A1

公开(公告)日：2021-03-25

申请号：US17030123

申请日：2020-09-23

Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM

Inventor： James B. BRUGAROLAS ,  Haley HILL ,  Tao WANG

IPC: A61K31/275 ,  G01N33/50

Abstract: The present disclosure provides methods of identifying patients who have partial or total resistance to HIF-2 inhibitors or who develop partial or total resistance to HIF-2 inhibitors after treatment and providing suitable treatment to these patients.