公开(公告)号：US20130157351A1

公开(公告)日：2013-06-20

申请号：US13769043

申请日：2013-02-15

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Aydogan Ozcan ,  Hongying Zhu

IPC: G01N21/64

CPC classification number: G01N21/6486 ,  G01N21/6458 ,  G01N21/648 ,  G01N2201/0221 ,  G02B7/006 ,  G02B7/02 ,  G02B13/0025 ,  G02B23/243 ,  H04M1/0254 ,  H04M1/21 ,  H04M2250/52 ,  H04N5/2254

Abstract: Wide-field fluorescent imaging on a mobile device having a camera is accomplished with a compact, light-weight and inexpensive optical components that are mechanically secured to the mobile device in a removable housing. Battery powered light-emitting diodes (LEDs) contained in the housing pump the sample of interest from the side using butt-coupling, where the pump light is guided within the sample holder to uniformly excite the specimen. The fluorescent emission from the sample is then imaged using an additional lens that is positioned adjacent to the existing lens of the mobile device. A color filter is sufficient to create the dark-field background required for fluorescent imaging, without the need for expensive thin-film interference filters.

Abstract translation: 具有照相机的移动设备上的宽场荧光成像通过紧凑，重量轻且廉价的光学部件来实现，该组件机械地固定到可拆卸外壳中的移动装置。 包含在壳体中的电池供电的发光二极管（LED）使用对接耦合从侧面泵送感兴趣的样品，其中泵浦光在样品保持器内引导以均匀地激发样品。 然后使用与移动装置的现有透镜相邻定位的附加透镜来成像来自样品的荧光发射。 滤色器足以产生荧光成像所需的暗场背景，而不需要昂贵的薄膜干涉滤光片。

公开(公告)号：US09057702B2

公开(公告)日：2015-06-16

申请号：US13769043

申请日：2013-02-15

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Aydogan Ozcan ,  Hongying Zhu

IPC: G01N21/64 ,  G01N21/00 ,  G02B23/24 ,  G02B7/00 ,  G02B7/02 ,  G02B13/00 ,  H04M1/02 ,  H04N5/225 ,  G01N21/76 ,  H04M1/21

CPC classification number: G01N21/6486 ,  G01N21/6458 ,  G01N21/648 ,  G01N2201/0221 ,  G02B7/006 ,  G02B7/02 ,  G02B13/0025 ,  G02B23/243 ,  H04M1/0254 ,  H04M1/21 ,  H04M2250/52 ,  H04N5/2254

Abstract: Wide-field fluorescent imaging on a mobile device having a camera is accomplished with a compact, light-weight and inexpensive optical components that are mechanically secured to the mobile device in a removable housing. Battery powered light-emitting diodes (LEDs) contained in the housing pump the sample of interest from the side using butt-coupling, where the pump light is guided within the sample holder to uniformly excite the specimen. The fluorescent emission from the sample is then imaged using an additional lens that is positioned adjacent to the existing lens of the mobile device. A color filter is sufficient to create the dark-field background required for fluorescent imaging, without the need for expensive thin-film interference filters.

Abstract translation: 具有照相机的移动设备上的宽场荧光成像通过紧凑，重量轻且廉价的光学部件来实现，该组件机械地固定到可拆卸外壳中的移动装置。 包含在壳体中的电池供电的发光二极管（LED）使用对接耦合从侧面泵送感兴趣的样品，其中泵浦光在样品保持器内引导以均匀地激发样品。 然后使用与移动装置的现有透镜相邻定位的附加透镜来成像来自样品的荧光发射。 滤色器足以产生荧光成像所需的暗场背景，而不需要昂贵的薄膜干涉滤光片。