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公开(公告)号:US20180296559A1
公开(公告)日:2018-10-18
申请号:US15724361
申请日:2017-10-04
Applicant: THE UNIVERSITY OF IOWA RESEARCH FOUNDATION
Inventor: David A. STOLTZ , Daniel COOK
IPC: A61K31/506 , A61K9/00 , A61K45/06 , A61P11/00
Abstract: The present disclosure is directed to compositions and methods for treating airway smooth muscle dysfunction in a subject. The compounds target the tyrosine protein kinase 2 beta. A particular dysfunction is asthma, including cystic fibrosis-induced asthma.