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公开(公告)号：US20240058168A1
公开(公告)日：2024-02-22
申请号：US18236375
申请日：2023-08-21
Applicant: TWENTY TWENTY THERAPEUTICS LLC
Inventor： Oleg Rumyantsev , Supriyo Sinha , Dimitri Azar , Kevin Luo , Michael Eyal
CPC classification number: A61F9/0026 , A61B34/76 , A61B2034/2057
Abstract: Systems and methods are provided for determining a likelihood that a drop released from a bottle will land in an eye of a user. Each of an eye of a user and a tip of a bottle and illuminated and imaged to provide at least one image. An orientation of the bottle is determined via an inertial measurement unit, and a likelihood that a drop released from the bottle will land in the eye of the user is determined from the determined orientation and the at least one image.
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公开(公告)号：US20230255481A1
公开(公告)日：2023-08-17
申请号：US18158365
申请日：2023-01-23
Applicant: Twenty Twenty Therapeutics LLC
Inventor： Supriyo Sinha , Oleg Rumyantsev , Jeremy Chan , Dimitri Azar
IPC: A61B3/16
CPC classification number: A61B3/16 , A61B2560/0214 , A61B2562/0247 , A61B2562/028
Abstract: An intraocular pressure sensing element along with implant microelectronic circuitry to be configured to be implanted into an eye of a user. The microelectronic circuitry is conductively coupled to the intraocular pressure sensing element to produce measured pressure data. A microscopic light emitting diode, LED, that is also implanted into the eye, is driven with the measured pressure data thereby optically transmitting the measured pressure data for communication with outside of the eye. A photovoltaic element that is also implanted into the eye supplies energy to operate the implant microelectronic circuitry and the microscopic LED. Other aspects are also described and claimed.
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公开(公告)号：US20230001207A1
公开(公告)日：2023-01-05
申请号：US17940433
申请日：2022-09-08
Applicant: Twenty Twenty Therapeutics LLC
Inventor： Dimitri Azar , Fred Shungneng Lee , Timothy Stowe
Abstract: According to some aspects, a device is presented herein that is configured to be located underneath an eyelid and worn by a user for treating dry eye. The device includes a first surface configured to face a portion of a sclera of the eye, and a second surface configured to face an eyelid and to be completely covered by the eyelid. In some embodiments, the device further includes a plurality of stimulation electrodes proximal to the first surface, wherein the plurality of stimulation electrodes is configured to stimulate the sclera. The device further includes an energy storage element coupled to the plurality of stimulation electrodes. The energy storage element is configured to supply power to the plurality of stimulation electrodes. The device further includes a processor configured to control a supply of energy from the energy storage element to the plurality of stimulation electrodes to stimulate the sclera.
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公开(公告)号：US11446495B2
公开(公告)日：2022-09-20
申请号：US15931241
申请日：2020-05-13
Applicant: Twenty Twenty Therapeutics LLC
Inventor： Dimitri Azar , Fred Shungneng Lee , Timothy Stowe
Abstract: According to some aspects, a device is presented herein that is configured to be located underneath an eyelid and worn by a user for treating dry eye. The device includes a first surface configured to face a portion of a sclera of the eye, and a second surface configured to face an eyelid and to be completely covered by the eyelid. In some embodiments, the device further includes a plurality of stimulation electrodes proximal to the first surface, wherein the plurality of stimulation electrodes is configured to stimulate the sclera. The device further includes an energy storage element coupled to the plurality of stimulation electrodes. The energy storage element is configured to supply power to the plurality of stimulation electrodes. The device further includes a processor configured to control a supply of energy from the energy storage element to the plurality of stimulation electrodes to stimulate the sclera.
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公开(公告)号：US20220226156A1
公开(公告)日：2022-07-21
申请号：US17609754
申请日：2020-03-23
Applicant: Twenty Twenty Therapeutics LLC
Inventor： Shungneng Lee , Dimitri Azar
Abstract: An intraocular micro-display system includes an intraocular micro-display (IOMD) implant and an auxiliary head unit for delivering power and image data to the IOMD implant. The IOMD implant includes an enclosure shaped for implantation into an eye, a micro-display to emit images towards a retina, an energy storage unit to power the micro-display, a charging antenna for wireless charging of the energy storage unit via a power signal incident upon the first charging antenna, and a data antenna to wirelessly receive the image data for driving the micro-display to emit the images. The charging antenna and the data antenna are implantable into the eye with the IOMD implant.
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Patent Agency Ranking
公开(公告)号：US20220031506A1
公开(公告)日：2022-02-03
申请号：US17391835
申请日：2021-08-02
Applicant: Twenty Twenty Therapeutics LLC
Inventor： Fred Shungneng Lee , Dimitri Azar
Abstract: In some aspects, an electronic contact lens for treating dry eye is presented. According to some aspects, the electronic contact lens includes a concave surface configured to conform to an eye of a patient, a sensor configured to generate a signal indicative of an eyelid movement, and at least one capacitor configured to store energy used for stimulating the eye. The electronic contact lens may further include at least two electrodes coupled to the at least one capacitor, wherein the at least two electrodes are exposed to the concave surface and configured to deliver power from the at least one capacitor to stimulate the eye. The electronic contact lens further includes a processor coupled to the sensor and electrodes. The processor may be configured to compute a blink rate from the sensor output, and, based on the blink rate, activate the at least two electrodes to stimulate the eye.
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公开(公告)号：US20240197168A1
公开(公告)日：2024-06-20
申请号：US18537645
申请日：2023-12-12
Applicant: Twenty Twenty Therapeutics LLC
Inventor： Supriyo Sinha , Kirk Gossage , Dimitri Azar
Abstract: Virtual reality, VR, headset-based electronic systems that can be used to perform visual field tests. The systems may improve the sensitivity, consistency, and case of application of the visual field test. Other aspects are also described.
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公开(公告)号：US20240148549A1
公开(公告)日：2024-05-09
申请号：US18382411
申请日：2023-10-20
Applicant: TWENTY TWENTY THERAPEUTICS LLC
Inventor： Alexandre R. Tumlinson , VanDee Moua , Dimitri Azar
IPC: A61F9/00
CPC classification number: A61F9/0017
Abstract: A vitrectomy device includes a body extending along an axis from a proximal end to a distal end and having a central passage. A needle is provided for insertion into the vitreous humor of an eye and extends within the central passage and out of the distal end of the body. An assembly including a chamber under vacuum and a piercing member extend away from the chamber. The chamber is movable in a direction transverse to the centerline from a first position in which the chamber is not fluidly connected to the needle to a second position in which the piercing member fluidly connects the chamber to the needle for drawing a vitreous sample into the chamber under vacuum pressure.
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公开(公告)号：US20240090766A1
公开(公告)日：2024-03-21
申请号：US18465913
申请日：2023-09-12
Applicant: Twenty Twenty Therapeutics LLC
Inventor： Supriyo Sinha , Dimitri Azar
CPC classification number: A61B3/152 , A61B3/0033 , A61B3/113 , A61B3/165 , A61B3/18
Abstract: A processor signals a display to show a target. Optics is positioned in an optical path taken by the target, as shown by the display, from the display to the eye of a user. The optics is configured to change accommodation by the eye and has adjustable focal length that enables the user to see the target with changing acuity. The processor then obtains an indication that the eye of the user is focused on the target. In response, the processor signals an alignment mechanism to align a sensor in the device to the eye of the user. After signaling the alignment mechanism to align the sensor to the eye of the user, the processor obtains sensor data, produced by the sensor, which measures a property of the eye. Other aspects are also described and claimed.
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公开(公告)号：US11918289B2
公开(公告)日：2024-03-05
申请号：US16872649
申请日：2020-05-12
Applicant: Twenty Twenty Therapeutics LLC
Inventor： Dimitri Azar , Kirk Gossage , Sam Kavusi , Prachi Shah
CPC classification number: A61B3/101 , A61B3/0008 , A61B5/6803 , A61B2562/0271 , A61B2562/029
Abstract: Disclosed is a headset for monitoring periocular humidity, the headset including a housing configured to be positioned on a user's face and defining a periocular air space. The headset includes a humidity sensor configured to measure a humidity of air within the periocular air space, and an ophthalmic testing unit configured to measure a physiological parameter of an eye of the user. The headset further includes a processor coupled to the humidity sensor and the ophthalmic testing unit. The processor is configured to receive the measured humidity and the measured physiological parameter, and determine an ophthalmic condition based on the measured humidity and the measured physiological parameter.
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