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    METHODS AND APPARATUSES FOR TREATMENT OF MEIBOMIAN GLAND DYSFUNCTION
    1.
    发明申请
    METHODS AND APPARATUSES FOR TREATMENT OF MEIBOMIAN GLAND DYSFUNCTION 审中-公开
    用于治疗脑血管性功能障碍的方法和装置

    公开(公告)号：US20150025545A1

    公开(公告)日：2015-01-22

    申请号：US14510843

    申请日：2014-10-09

    Applicant: TearScience, Inc.

    Inventor： Stephen M. Grenon ,  John Martin Jans ,  Jordan W. Hutchinson ,  Keith Gausmann

    IPC: A61B17/22 ,  A61F7/02

    CPC classification number: A61F9/00772 ,  A61B17/22 ,  A61B18/08 ,  A61B18/12 ,  A61B2017/00084 ,  A61B2017/22082 ,  A61B2018/046 ,  A61B2018/048 ,  A61F7/007 ,  A61F7/02 ,  A61F7/12 ,  A61F2007/0004 ,  A61F2007/0059 ,  A61F2007/0071 ,  A61F2007/0086 ,  A61F2007/0091 ,  A61F2007/0096 ,  A61F2007/0249 ,  A61F2007/0282 ,  A61H7/00 ,  A61H2015/0014 ,  A61N7/00

    Abstract: A method of treating meibomian gland dysfunction is disclosed that comprises applying heat to an outer surface of a patient's eyelid to a temperature level to melt, loosen, or soften an obstruction located within a meibomian gland. The method also comprises maintaining the heat to the outer surface of the patient's eyelid for a period of time. The method further comprises applying a pressure to the outer surface of the patient's eyelid to express the obstruction from the meibomian gland. The obstruction may be located within a meibomian gland channel of the meibomian gland and the method may comprise expressing the obstruction located within a meibomian gland channel through a meibomian gland orifice. Applying the pressure may be done by positioning a pressure applicator into contact with the outer surface of the patient's eyelid and applying a pressure with the pressure applicator over a substantial portion of the patient's eyelid.

    Abstract translation: 公开了一种治疗睑板腺功能障碍的方法，其包括将热量施加到患者眼睑的外表面至达到熔化，松动或软化位于睑板腺内的梗阻的温度水平。 该方法还包括将热量保持到患者眼皮的外表面一段时间。 该方法还包括向患者的眼皮的外表面施加压力以表达来自睑板腺的阻塞。 梗阻可以位于睑板腺的睑板腺通道内，并且该方法可以包括通过睑板腺口表达位于睑板腺通道内的阻塞物。 施加压力可以通过将压力施加器定位成与患者的眼皮的外表面接触并且将压力施加器施加在患者眼睑的大部分上的压力来进行。

    METHODS AND APPARATUSES FOR TREATMENT OF MEIBOMIAN GLAND DYSFUNCTION
    2.
    发明申请
    METHODS AND APPARATUSES FOR TREATMENT OF MEIBOMIAN GLAND DYSFUNCTION 有权

    公开(公告)号：US20210205131A1

    公开(公告)日：2021-07-08

    申请号：US17208465

    申请日：2021-03-22

    Applicant: TearScience, Inc.

    Inventor： Stephen M. Grenon ,  John Martin Jans ,  Jordan W. Hutchinson ,  Keith Gausmann ,  Donald R. Korb

    IPC: A61F9/007 ,  A61F7/00 ,  A61H7/00 ,  A61F7/12 ,  A61B17/22 ,  A61F7/02

    Abstract: Apparatus and methods for treating dry eye include an energy source configured to apply energy to an obstruction located in a meibomian gland of a patient's eyelid. The apparatus also comprises an insulator configured to be positioned between a rear portion of the patient's eyelid and a surface of the patient's eyeball. An inner surface of the insulator has a curvature greater than that of the patient's eyeball such that an air pocket is formed between the inner surface of the insulator and the patient's eyeball, wherein the air pocket provides additional insulation to reduce or eliminate an amount of heat due to the applied energy from the energy source from being conducted to the surface of the patient's eyeball, such that the applied energy does not cause the temperature to reach a temperature sufficient to cause damage to a corneal or scleral portion of the patient's eyeball.

    METHODS, APPARATUSES, AND SYSTEMS FOR REDUCING INTRAOCULAR PRESSURE AS A MEANS OF PREVENTING OR TREATING OPEN-ANGLE GLAUCOMA
    4.
    发明申请
    METHODS, APPARATUSES, AND SYSTEMS FOR REDUCING INTRAOCULAR PRESSURE AS A MEANS OF PREVENTING OR TREATING OPEN-ANGLE GLAUCOMA 有权
    用于减少眼压的方法，装置和系统作为预防或治疗开放性角膜炎的手段

    公开(公告)号：US20140066821A1

    公开(公告)日：2014-03-06

    申请号：US14074123

    申请日：2013-11-07

    Applicant: TearScience, Inc.

    Inventor： Beth Friedland ,  Donald R. Korb ,  Steve Grenon ,  John Jans ,  Keith Gausmann ,  Timothy R. Willis

    IPC: A61B18/04 ,  A61H1/00

    CPC classification number: A61B18/04 ,  A61B18/10 ,  A61B2018/00642 ,  A61B2018/00791 ,  A61B2018/046 ,  A61B2018/048 ,  A61F9/00781 ,  A61F2007/0004 ,  A61F2007/0059 ,  A61F2007/0071 ,  A61H1/008 ,  A61N7/00

    Abstract: Embodiments include methods, apparatuses, and systems for reducing elevated intraocular pressure (IOP) in a patient to either prevent or treat open-angle glaucoma. Heat is applied to the trabecular meshwork in the patient's eye without damaging proteins in the trabecular meshwork. The application of heat to the trabecular meshwork has the effect of relaxing or loosening protein clogs or other inhibitors in the trabecular meshwork, which are either reducing or obstructing of the outflow of aqueous humor, thereby increasing the patient's IOP and causing ocular hypertension (OHT). By loosening or relaxing clogs or other inhibitors in the trabecular meshwork, the outflow path for aqueous humor is increased or restored, which can lower IOP and either prevent or treat glaucoma. Force may also be applied to the patient's eye to apply pressure to the trabecular meshwork to further assist in the loosening or relaxing of clogs or other inhibitors in the trabecular meshwork.

    Abstract translation: 实施方案包括用于降低患者眼内压升高（IOP）以预防或治疗开角型青光眼的方法，装置和系统。 热量被施加到患者眼睛中的小梁网，而不损伤小梁网中的蛋白质。 对小梁网应用热量具有放松或松动小梁网中的蛋白质堵塞物或其他抑制剂的作用，其减少或阻碍房水流出，从而增加患者的眼压并引起眼高压（OHT） 。 通过在小梁网中松动或松弛堵塞物或其他抑制剂，房水的流出路径增加或恢复，这可以降低IOP并预防或治疗青光眼。 力也可以应用于患者的眼睛，以向小梁网施加压力，以进一步协助松动或松弛小梁网中的堵塞物或其它抑制剂。

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