公开(公告)号：US20240124903A1

公开(公告)日：2024-04-18

申请号：US18318424

申请日：2023-05-16

Applicant: The Regents of the University of California

Inventor： Zhiliang Fan

IPC: C12P7/10 ,  C12P1/02

CPC classification number: C12P7/10 ,  C12P1/02 ,  C12P2201/00

Abstract: The present disclosure provides methods for producing fuels, such as biofuels, and commodity chemicals. In some embodiments, the methods comprise pretreating cellulosic biomass with a sugar acid. In some embodiments, the methods further comprise recycling sugar acids that are produced during fermentation for use in the subsequent pretreatment of cellulosic biomass. In some embodiments, the methods further comprise utilizing one or more components produced during pretreatment for subsequent fermentation. Fuels and commodity chemicals produced according to the methods of the present invention are also provided herein.

公开(公告)号：US10358668B2

公开(公告)日：2019-07-23

申请号：US15307803

申请日：2015-04-28

Applicant: The Regents of the University of California

Inventor： Zhiliang Fan ,  Amanda Hildebrand

IPC: C12P19/12 ,  C12N9/42 ,  C12N15/00 ,  C07H21/04 ,  C07H21/02 ,  C12N1/14 ,  C12N15/80 ,  C07K14/37 ,  C12P19/44 ,  C12N9/04 ,  C12N9/02 ,  C12N9/10

Abstract: The present disclosure generally relates to biological platforms for the conversion of cellulosic biomass into fuels and chemicals. More specifically, the present disclosure relates to the conversion of cellulosic materials into sugar acids or their salts, which may then be used to produce commodity chemicals. In one aspect, the present disclosure relates to a recombinant host cell including: reduced activity of one or more polypeptides having P-glucosidase activity as compared to a corresponding wild type cell, where each of said one or more polypeptides are encoded by a gene that has at least 80% sequence identity to a gene.