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公开(公告)号：US10094823B2
公开(公告)日：2018-10-09
申请号：US14604396
申请日：2015-01-23
Applicant: Tokitae LLC
Inventor： Matthew P. Horning , Kevin Paul Flood Nichols , Benjamin K. Wilson
IPC: G01N21/00 , G01N33/558 , G01N33/543 , G01N33/553 , G01N21/17 , G01N21/84
Abstract: Embodiments disclosed herein are directed to a photothermal spectroscopy assay reader including a light source configured to emit light in the red range of the light spectrum. Methods of operating such photothermal spectroscopy assay readers are also disclosed. Assay kits including a lateral flow assay and a photothermal spectroscopy assay reader configured to read the photothermal spectroscopy assay reader are also disclosed.
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公开(公告)号：US10061972B2
公开(公告)日：2018-08-28
申请号：US15433656
申请日：2017-02-15
Applicant: Tokitae LLC
Inventor： Cary Richard Champlin , Charles Delahunt , Matthew P. Horning , Liming Hu , Shawn Keith McGuire , Courosh Mehanian , Clay Matthew Thompson , Benjamin K. Wilson
CPC classification number: G06K9/0014 , G01N33/49 , G02B21/365 , G06K9/00147 , G06K9/4652 , G06T7/0012 , G06T2207/10024 , G06T2207/30004
Abstract: Embodiments disclosed herein are directed to systems and methods for determining a presence and an amount of an analyte in a biological sample. The systems and methods for determining the presence of an analyte utilize a plurality of images of a sample slide including multiple fields-of-view having multiple focal planes therein. The systems and methods utilize algorithms configured to balance the color and grayscale intensity of the plurality of images and based thereon determine if the plurality of images contain the analyte therein.
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公开(公告)号：US20170161545A1
公开(公告)日：2017-06-08
申请号：US15433656
申请日：2017-02-15
Applicant: Tokitae LLC
Inventor： Cary Richard Champlin , Charles Delahunt , Matthew P. Horning , Liming Hu , Shawn Keith McGuire , Courosh Mehanian , Clay Matthew Thompson , Benjamin K. Wilson
CPC classification number: G06K9/0014 , G01N33/49 , G02B21/365 , G06K9/00147 , G06K9/4652 , G06T7/0012 , G06T2207/10024 , G06T2207/30004
Abstract: Embodiments disclosed herein are directed to systems and methods for determining a presence and an amount of an analyte in a biological sample. The systems and methods for determining the presence of an analyte utilize a plurality of images of a sample slide including multiple fields-of-view having multiple focal planes therein. The systems and methods utilize algorithms configured to balance the color and grayscale intensity of the plurality of images and based thereon determine if the plurality of images contain the analyte therein.
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公开(公告)号：US09453996B2
公开(公告)日：2016-09-27
申请号：US14061009
申请日：2013-10-23
Applicant: Tokitae LLC
Inventor： Charles Delahunt , David Gasperino , Matthew P. Horning , Kevin P. F. Nichols , Benjamin K. Wilson
CPC classification number: G02B21/34 , B01L3/5023 , B01L3/50273 , B01L9/527 , B01L2300/0816 , B01L2300/0822 , B01L2400/0406 , C12Q2563/107 , G01N1/312
Abstract: Devices and methods for preparing and assessing a liquid sample are described which include: a microfluidic microscopy device including an absorbent structure including at least one dry dye for a liquid and configured to convey a polar liquid from a first end of the absorbent structure through the at least one dry dye for a liquid to a second end of the absorbent structure, a support structure positioned adjacent to a first surface of the absorbent structure, a lid structure positioned adjacent to a second surface of the absorbent structure, and a clamping structure positioned to maintain a relative position of the support structure and the lid structure to form a tapered internal chamber adjacent to the second end of the absorbent structure.
Abstract translation: 描述了用于制备和评估液体样品的装置和方法，其包括：微流体显微镜装置，其包括吸收结构，所述吸收结构包括用于液体的至少一种干染料，并且被配置为通过所述吸收结构的吸收结构的第一端输送极性液体 至少一个用于液体的干染料到吸收结构的第二端，邻近吸收结构的第一表面定位的支撑结构，邻近吸收结构的第二表面定位的盖结构，以及夹持结构，其定位成 保持支撑结构和盖结构的相对位置，以形成与吸收结构的第二端相邻的锥形内腔。
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5.发明申请PHOTOTHERMAL SPECTROSCOPY ASSAY READERS, AND RELATED ASSAY KITS AND METHODS 审中-公开光电光谱测定读数器及相关测定工具及方法公开(公告)号：US20160216260A1
公开(公告)日：2016-07-28
申请号：US14604396
申请日：2015-01-23
Applicant: Tokitae LLC
Inventor： Matthew P. Horning , Kevin Paul Flood Nichols , Benjamin K. Wilson
IPC: G01N33/558 , G01N33/543 , G01N33/553 , G01N25/48
CPC classification number: G01N33/558 , G01N21/171 , G01N21/8483 , G01N33/54346 , G01N33/54386 , G01N33/553 , G01N2021/1714
Abstract: Embodiments disclosed herein are directed to a photothermal spectroscopy assay reader including a light source configured to emit light in the red range of the light spectrum. Methods of operating such photothermal spectroscopy assay readers are also disclosed. Assay kits including a lateral flow assay and a photothermal spectroscopy assay reader configured to read the photothermal spectroscopy assay reader are also disclosed.
Abstract translation: 本文公开的实施例涉及光热谱测定读取器，其包括被配置为发射在光谱的红色范围内的光的光源。 还公开了操作这种光热光谱测定读取器的方法。 还公开了包括侧流测定法和配置成读取光热光谱测定读数器的光热光谱测定读数器的测定试剂盒。
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Patent Agency Ranking
公开(公告)号：US09836839B2
公开(公告)日：2017-12-05
申请号：US15154824
申请日：2016-05-13
Applicant: Tokitae LLC
Inventor： Cary Richard Champlin , Charles Delahunt , Matthew P. Horning , Liming Hu , Shawn Keith McGuire , Courosh Mehanian , Clay Matthew Thompson , Benjamin K. Wilson
CPC classification number: G06T7/0012 , G06K9/00147 , G06K9/4652 , G06T2207/10024 , G06T2207/10056 , G06T2207/10148 , G06T2207/20084 , G06T2207/30004 , G06T2207/30024
Abstract: Embodiments disclosed herein are directed to systems and methods for determining a presence and an amount of an analyte in a biological sample. The systems and methods for determining the presence of an analyte utilize a plurality of images of a sample slide including multiple fields-of-view having multiple focal planes therein. The systems and methods utilize algorithms configured to color and grayscale intensity balance the plurality of images and based thereon determine if the plurality of images contain the analyte therein.
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公开(公告)号：US09625385B2
公开(公告)日：2017-04-18
申请号：US14630489
申请日：2015-02-24
Applicant: Tokitae LLC
Inventor： David Gasperino , Matthew P. Horning , Kevin Paul Flood Nichols , Phil Rutschman , Benjamin K. Wilson , Ozgur Emek Yildirim
IPC: G01J5/02 , G01N21/63 , G01N33/543 , G01N21/17
CPC classification number: G01N21/63 , G01N21/171 , G01N33/54373 , G01N2021/1714 , G01N2201/0697
Abstract: Embodiments disclosed herein are directed to photothermal spectroscopy apparatuses and systems for offset synchronous testing of flow assays. Methods of using and operating such photothermal spectroscopy systems are also disclosed.
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公开(公告)号：US20140294280A1
公开(公告)日：2014-10-02
申请号：US14307724
申请日：2014-06-18
Applicant: Tokitae LLC
Inventor： Matthew R. Behrend , Michael C. Hegg , Matthew P. Horning , Benjamin K. Wilson
CPC classification number: G06K9/00147 , A61B3/1233 , A61B5/0059 , A61B5/0062 , A61B5/05 , A61B5/14546 , A61B8/06 , A61B2562/0238 , G01N21/49 , G01N2333/445 , G06K9/6212 , G06T7/0014 , G06T2207/20076 , G06T2207/30024
Abstract: Systems, devices, and methods are described for providing a monitor or treatment device configured to, for example, detect hemozoin, as well as to monitor or treat a malarial infection.
Abstract translation: 描述了用于提供被配置为例如检测血红蛋白以及监测或治疗疟疾感染的监测器或治疗装置的系统，装置和方法。
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公开(公告)号：US10132743B2
公开(公告)日：2018-11-20
申请号：US15217493
申请日：2016-07-22
Applicant: GENERAL ELECTRIC COMPANY , TOKITAE LLC
Inventor： Ralf Lenigk , Mark Marshall Meyers , Victor Petrovich Ostroverkhov , Timothy Toepfer , Keith Michael Looney , Terry Lee Saunders , Kevin Paul Flood Nichols , Matthew P. Horning , Benjamin K. Wilson , Daniel Keith Connors , David Gasperino
Abstract: Disclosed is a low-cost, portable photo thermal spectroscopy (PTS) reader for use in detecting the presence of diseases in the bodily fluid of affected patients. The PTS reader is designed to be durable, easy to use and provide readings from the Lateral Flow Assay (LFA) with rapid results. Also provided are methods of use.
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公开(公告)号：US09524417B2
公开(公告)日：2016-12-20
申请号：US14307724
申请日：2014-06-18
Applicant: Tokitae LLC
Inventor： Matthew R. Behrend , Michael C. Hegg , Matthew P. Horning , Benjamin K. Wilson
IPC: G06K9/00 , A61B3/12 , A61B5/00 , A61B5/145 , G01N21/49 , G06K9/62 , G06T7/00 , A61B5/05 , A61B8/06
CPC classification number: G06K9/00147 , A61B3/1233 , A61B5/0059 , A61B5/0062 , A61B5/05 , A61B5/14546 , A61B8/06 , A61B2562/0238 , G01N21/49 , G01N2333/445 , G06K9/6212 , G06T7/0014 , G06T2207/20076 , G06T2207/30024
Abstract: Systems, devices, and methods are described for providing a monitor or treatment device configured to, for example, detect hemozoin, as well as to monitor or treat a malarial infection.
Abstract translation: 描述了用于提供被配置为例如检测血红蛋白以及监测或治疗疟疾感染的监测器或治疗装置的系统，装置和方法。
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