公开(公告)号：US20150038043A1

公开(公告)日：2015-02-05

申请号：US14293308

申请日：2014-06-02

Applicant: Trustees of Tufts College

Inventor： David L. KAPLAN ,  Ung-Jin KIM ,  Jaehyung PARK ,  Hyoung-Joon JIN

IPC: A61L27/22 ,  B29D7/01 ,  B29C39/20 ,  B29C39/00 ,  B29C55/00

CPC classification number: A61L27/227 ,  A61L27/3604 ,  A61L27/38 ,  A61L27/52 ,  A61L27/56 ,  A61L2430/02 ,  B29C39/003 ,  B29C39/203 ,  B29C55/005 ,  B29D7/01 ,  B29K2089/00 ,  B29L2007/00 ,  B29L2009/00 ,  C07K14/43536 ,  C07K14/43586 ,  C08J3/07 ,  C08J3/075 ,  C08J5/18 ,  C08J9/0061 ,  C08J9/26 ,  C08J9/28 ,  C08J2201/0444 ,  C08J2201/0504 ,  C08J2205/022 ,  C08J2389/00 ,  C08L89/00 ,  D01D5/0007 ,  D01F4/02 ,  Y10T428/249921 ,  Y10T442/10 ,  Y10T442/60

Abstract: The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.