公开(公告)号：US20190248890A1

公开(公告)日：2019-08-15

申请号：US16271086

申请日：2019-02-08

Applicant: UCB Biopharma SPRL

Inventor： Helene Margaret Finney ,  Alastair David Griffiths Lawson ,  Stevan Graham Shaw ,  Bryan John Smith ,  Kerry Louise Tyson ,  Lara Kevorkian ,  Christoph Meier ,  Kaushik Sarkar ,  Paul Alan Atherfold

IPC: C07K16/28 ,  A61K39/395 ,  A61K47/64 ,  G01N33/50 ,  G01N33/564 ,  G01N33/68 ,  A61K47/60

CPC classification number: C07K16/283 ,  A61K39/3955 ,  A61K47/60 ,  A61K47/643 ,  A61K2039/505 ,  C07K2317/21 ,  C07K2317/24 ,  C07K2317/33 ,  C07K2317/55 ,  C07K2317/565 ,  C07K2317/76 ,  C07K2317/92 ,  G01N33/5047 ,  G01N33/564 ,  G01N33/6854 ,  G01N33/6857 ,  G01N33/6893 ,  G01N2333/70535 ,  G01N2500/02 ,  G01N2500/10 ,  G01N2800/104 ,  G01N2800/24 ,  G01N2800/28

Abstract: The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.

公开(公告)号：US20150118240A1

公开(公告)日：2015-04-30

申请号：US14400812

申请日：2013-05-13

Applicant: UCB Biopharma SPRL

Inventor： Helene Margaret Finney ,  Alastair David Griffiths Lawson ,  Stevan Graham Shaw ,  Bryan John Smith ,  Kerry Louise Tyson ,  Lara Kevorkian ,  Christoph Meier ,  Kaushik Sarkar ,  Paul Alan Atherfold

IPC: C07K16/28 ,  G01N33/50 ,  G01N33/68 ,  A61K47/48 ,  A61K39/395

CPC classification number: C07K16/283 ,  A61K39/3955 ,  A61K47/60 ,  A61K47/643 ,  A61K2039/505 ,  C07K2317/21 ,  C07K2317/24 ,  C07K2317/33 ,  C07K2317/55 ,  C07K2317/565 ,  C07K2317/76 ,  C07K2317/92 ,  G01N33/5047 ,  G01N33/564 ,  G01N33/6854 ,  G01N33/6857 ,  G01N33/6893 ,  G01N2333/70535 ,  G01N2500/02 ,  G01N2500/10 ,  G01N2800/104 ,  G01N2800/24 ,  G01N2800/28

Abstract: The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.

Abstract translation: 本公开涉及对FcRn特异性的抗体，包含其的制剂，治疗中的每一种的使用，用于表达和任选配制所述抗体的方法，编码抗体的DNA和包含所述DNA的宿主。

公开(公告)号：US11384148B2

公开(公告)日：2022-07-12

申请号：US16271086

申请日：2019-02-08

Applicant: UCB Biopharma SPRL

Inventor： Helene Margaret Finney ,  Alastair David Griffiths Lawson ,  Stevan Graham Shaw ,  Bryan John Smith ,  Kerry Louise Tyson ,  Lara Kevorkian ,  Christoph Meier ,  Kaushik Sarkar ,  Paul Alan Atherfold

IPC: A61K39/395 ,  A61K39/40 ,  C07K16/28 ,  G01N33/50 ,  G01N33/564 ,  G01N33/68 ,  A61K47/60 ,  A61K47/64 ,  C07K16/00 ,  A61K39/00

Abstract: The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.

公开(公告)号：US11492396B2

公开(公告)日：2022-11-08

申请号：US15771310

申请日：2016-10-26

Applicant: UCB BIOPHARMA SPRL

Inventor： Sophie Glatt ,  Lucian Ionescu ,  Margaret Jones ,  Ruth Oliver ,  Stevan Graham Shaw ,  Foteini Strimenopoulou ,  Venkata Pavan Kumar Vajjah

IPC: A61K39/395 ,  C07K16/24 ,  A61P17/06 ,  A61P19/02 ,  A61K39/00

Abstract: The invention relates to therapeutic uses of antibody molecules having specificity for antigenic determinants of both IL-17A and IL-17F in the treatment of dermatological and rheumatological diseases, such as psoriasis, psoriatic arthritis and axial spondyloarthritis.

公开(公告)号：US20190292255A1

公开(公告)日：2019-09-26

申请号：US15771310

申请日：2016-10-26

Applicant: UCB BIOPHARMA SPRL

Inventor： Sophie Glatt ,  Lucian Ionescu ,  Margaret Jones ,  Ruth Oliver ,  Stevan Graham Shaw ,  Foteini Strimenopoulou ,  Venkata Pavan Kumar Vajjah

IPC: C07K16/24 ,  A61P19/02 ,  A61P17/06

Abstract: The invention relates to therapeutic uses of antibody molecules having specificity for antigenic determinants of both IL-17A and IL-17F in the treatment of dermatological and rheumatological diseases, such as psoriasis, psoriatic arthritis and axial spondyloarthritis.

公开(公告)号：US10233243B2

公开(公告)日：2019-03-19

申请号：US14400812

申请日：2013-05-13

Applicant: UCB Biopharma SPRL

Inventor： Helene Margaret Finney ,  Alastair David Griffiths Lawson ,  Stevan Graham Shaw ,  Bryan John Smith ,  Kerry Louise Tyson ,  Lara Kevorkian ,  Christoph Meier ,  Kaushik Sarkar ,  Paul Alan Atherfold

IPC: C07K16/00 ,  C12P21/08 ,  A61K39/395 ,  C07K16/28 ,  G01N33/50 ,  G01N33/564 ,  G01N33/68 ,  A61K47/60 ,  A61K47/64 ,  C07K1/00 ,  A61K39/00

Abstract: The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.