公开(公告)号：US20240043456A1

公开(公告)日：2024-02-08

申请号：US18032944

申请日：2020-11-10

Applicant: Unity Biotechnology, Inc.

Inventor： Liang Liao ,  Yuxi Ning ,  Jane Li ,  Yue Lu ,  Albert Shi ,  Nathan Guz

IPC: C07F9/6558

CPC classification number: C07F9/65583 ,  C07B2200/13

Abstract: Provided are the crystalline solid meglumine salts of (R)-5-(4-chlorophenyl)-1-isopropyl-2-methyl-4-(3-(4-(4-((4-((1-(phenylthio)-4-(4-((phosphonooxy)methyl)piperidin-1-yl)butan-2-yl)amino)-3- ((trifluoromethyl)sulfonyl)phenyl)sulfonamido)phenyl) piperazin-1-yl)phenyl)-1H-pyrrole-3-carboxylic acid. Pharmaceutical compositions having one or more of the crystalline solid meglumine salt compounds and methods for administering the crystalline solid meglumine salt compounds to a subject are also described. Methods for preparing the crystalline solid meglumine salt compounds are also provided.