公开(公告)号：US12150973B2

公开(公告)日：2024-11-26

申请号：US17051341

申请日：2019-04-17

Applicant: University of Utah Research Foundation

Inventor： Dean Tantin

IPC: A61K38/16 ,  A61K9/00 ,  A61K38/08 ,  A61K47/64 ,  A61P19/02

Abstract: Disclosed herein, are compounds comprising a peptide, wherein the peptide is OCA-B or an OCA-B fragment thereof; a linker; and a cell penetrating peptide. Also described herein, are methods of administering compounds to subjects for the treatment of Type I diabetes and blocking the interaction between OCA-B and Jmjd1a.

公开(公告)号：US20210046153A1

公开(公告)日：2021-02-18

申请号：US17051341

申请日：2019-04-17

Applicant: University of Utah Research Foundation

Inventor： Dean Tantin

IPC: A61K38/16 ,  A61K9/00 ,  A61P19/02 ,  A61K47/64

Abstract: Disclosed herein, are compounds comprising a peptide, wherein the peptide is OCA-B or an OCA-B fragment thereof; a linker; and a cell penetrating peptide. Also described herein, are methods of administering compounds to subjects for the treatment of Type I diabetes and blocking the interaction between OCA-B and Jmjd1a.