公开(公告)号：US20220373560A1

公开(公告)日：2022-11-24

申请号：US17767250

申请日：2020-10-08

Applicant: University of Utah Research Foundation

Inventor： Kathryn A. Peterson ,  Gerald J. Gleich ,  Mark D. Yandell ,  Edwin Lin ,  Hedieh Saffari

IPC: G01N33/68

Abstract: Disclosed are methods of diagnosing and treating a subject with active or inactive eosinophilic esophagitis (EoE). The methods may include the steps of detecting whether a level of one or more immunoglobulin antibodies is elevated in an esophageal secretion sample obtained from a subject, diagnosing the subject with active EoE when the level of one or more immunoglobulin antibodies in the sample is elevated above a pre-determined cut-off value and diagnosing the subject with inactive EoE when the level of one or more immunoglobulin antibodies level in the sample is below a pre-determined cut-off value; and treating the subject diagnosed with active EoE.