公开(公告)号：US20210046633A1

公开(公告)日：2021-02-18

申请号：US16663594

申请日：2019-10-25

Applicant: Yi-Cheng LI

Inventor： Yi-Cheng LI

IPC: B25G1/04

Abstract: A wrench includes a tool head, an outer tube unit, a rod unit and a sleeve unit. The outer tube unit includes an outer tube, a tail seat and a biasing member. The tail seat is detachably mounted to the outer tube. The rod unit includes an inner rod telescopically disposed in the outer tube and formed with a plurality of cavities. The biasing member biases the inner rod away from the tail seat. The sleeve unit is slidably sleeved on the outer tube and includes a positioning ball engageable with a selected one of the cavities to prevent the inner rod from moving relative to the outer tube and removable from the selected one of the cavities to allow the inner rod to move relative to the outer tube.

公开(公告)号：US20120183504A1

公开(公告)日：2012-07-19

申请号：US13006432

申请日：2011-01-14

Applicant: Ying-Chen LU ,  Jau-Shyang HUANG ,  Feng-Ching HSIEH ,  Yi-Cheng LI ,  Chia-Lin LEE

Inventor： Ying-Chen LU ,  Jau-Shyang HUANG ,  Feng-Ching HSIEH ,  Yi-Cheng LI ,  Chia-Lin LEE

IPC: A61K35/74 ,  A61P13/12 ,  A61P3/10

CPC classification number: A61K35/747 ,  A61K35/745 ,  A61K2300/00

Abstract: A use of probiotic strain GM-263 (ADR-1) in treating renal fibrosis in diabetes is disclosed. The probiotic strain such as Lactobacillus renteri strain GM-263 (ADR-1) (accession No. CCTCC M 209263) is utilized to produce a composition for treating renal fibrosis in diabetes in an effective dose, thereby reducing the concentration of glycated hemoglobin and blood sugar and keeping body weight and kidney weight within normal range, as well as specifically inhibiting phosphorylation of JAK2/STAT1 signal transduction pathway and renal fibrosis-related protein expression.

Abstract translation: 公开了益生菌菌株GM-263（ADR-1）在治疗糖尿病肾纤维化中的应用。 益生菌菌株如转基因乳杆菌菌株GM-263（ADR-1）（登录号CCTCC M 209263）用于产生有效剂量治疗糖尿病肾纤维化的组合物，从而降低糖化血红蛋白和血液的浓度 糖和保持体重和肾脏重量在正常范围内，以及特异性抑制JAK2 / STAT1信号转导通路和肾纤维化相关蛋白表达的磷酸化。