公开(公告)号：US12259327B2

公开(公告)日：2025-03-25

申请号：US17616786

申请日：2020-06-05

Applicant: ZILIA INC.

Inventor： Nicolas Lapointe ,  Damon Depaoli ,  Dominic Sauvageau

IPC: G01N21/64 ,  A61B3/12 ,  A61B3/14 ,  A61B5/00 ,  G01N21/65

Abstract: Systems and methods for performing a photoluminescence analysis on a medium such as the fundus of a patient's eye are provided. An imaging device, a spectral analyser and an excitation light source are provided. An optical assembly defines an imaging light path between the patient's eye and the imaging device and a spectral analysis light path between an analysis spot on the patient's eye and the spectral analyser. The excitation light source generates an excitation light beam comprising an excitation wavelength selected to excite components present in the patient's eye for the generation of fluorescent light at a photoluminescence wavelength, and is optically coupled to the spectral analysis light path for projecting the excitation light beam on the analysis spot. An optical filter is coupled to the spectral analyser, and has a low light transmissivity at the excitation wavelength and a high light transmissivity at the photoluminescence wavelength.